Treatment
Comparator clinical trials
We’re tracking 1,699 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT06220526Recruiting
Comparing needles for chest lymph node biopsy in sarcoidosis
This trial compares two types of needles used during a breathing-tube biopsy (EBUS-TBNA) to see which one works better for diagnosing sarcoidosis in people with enlarged chest lymph nodes.
Toronto, OntarioAges 18 years+ - NCT06221631Recruiting
Brain aging in MS and healthy people
This study compares how the brain ages in people with multiple sclerosis (MS) and healthy volunteers. It uses MRI scans and other tests to understand brain aging better.
Bern, Canton of BernAges 18–65 - NCT06209684Recruiting
Carbon fiber screws vs titanium for spine surgery
This trial compares a new carbon fiber screw system to standard titanium screws for people needing spinal fusion surgery to treat degenerative spine conditions. It aims to see which type of screw works better for pain and stability.
BolognaAges 18 years+ - NCT06224283Recruiting
Predicting desmoid tumor growth after cryoablation
This study looks at whether a special MRI analysis (radiomics) can better predict if a desmoid tumor will grow back after freezing treatment (cryoablation) compared to standard methods. It may help doctors decide on future treatment steps.
BolognaAges Any age - NCT04095676Recruiting
Surgery vs drainage for infected fluid around the lung
This trial compares two ways to treat pleural empyema, which is infected fluid and pus around the lung. It looks at whether a minimally invasive surgery (VATS) works better than drainage in helping people recover.
Aarhus, AarhusAges 18 years+ - NCT06205095RecruitingPhase 3
Wilate for heavy menstrual bleeding in von Willebrand disease
This trial tests whether a medicine called Wilate, given regularly (prophylaxis), can reduce heavy menstrual bleeding in women with von Willebrand disease. It compares Wilate to a placebo (a dummy treatment) to see if it helps more than no treatment.
Kingston, OntarioAges 18 years+ - NCT05377034RecruitingPhase 2
Y-90 and immunotherapy vs Y-90 plus placebo for liver cancer
This phase 2 study tests whether adding immunotherapy drugs (atezolizumab and bevacizumab) after Y-90 treatment works better and is safe compared with Y-90 followed by placebo. It is for people with liver cancer that has not spread outside the liver but is difficult to treat.
BeijingAges 21–99 - NCT06180902Recruiting
Testing fluid response methods in patients with reduced consciousness
This trial compares different ways to check if a patient in the ICU with lowered consciousness needs more IV fluids. It aims to find the most accurate method, which could help doctors give the right amount of fluid.
MoscowAges 18 years+ - NCT06173401RecruitingPhase 3
Single vs. multiple radiation sessions for spine tumors
This trial is testing whether a single radiation treatment to spine tumors works as well as multiple smaller treatments. It may be an option if you have cancer that has spread to up to 3 spots in your spine.
Palo Alto, CaliforniaAges 18 years+ - NCT06170541Recruiting
Comparing heart artery scans for coronary disease
This study tests whether a newer CT scan method can better detect coronary heart disease. You may qualify if your doctor referred you for a heart CT scan.
Baltimore, MarylandAges 21–85 - NCT06158581Recruiting
Comparing two emotion therapies for autistic youth and adults
This study compares two different types of emotional support therapies to see which works better for autistic youth and young adults who have high emotional reactivity or distress. You'll be asked about your feelings and experiences, and your support person (like a parent or friend) can help answer questions too.
Tuscaloosa, AlabamaAges 10–30 - NCT06136559RecruitingPhase 3
Study of Nemtabrutinib vs ibrutinib or acalabrutinib for untreated CLL/SLL
This trial tests a new drug, nemtabrutinib, against two standard treatments for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who haven't had treatment yet. The goal is to see if the new drug works better at controlling the disease.
Mobile, AlabamaAges 18 years+ - NCT06130371Recruiting
Stress, Inflammation & Brain in Depression vs. Severe PMS
This study looks at how stress and inflammation affect the brain in women with major depression compared to women with severe PMS (PMDD). It could help find better ways to understand and treat these mood disorders.
Tübingen, Baden-WurttembergAges 18–40 - NCT06131281Recruiting
Comparing two endoscopic procedures for weight regain after gastric bypass
This study compares two endoscopic procedures used to help people who have regained weight after gastric bypass surgery. The goal is to see which procedure is more effective at reducing the size of the connection between the stomach and intestine to help with weight loss.
Cleveland, OhioAges 18 years+ - NCT06152705Recruiting
fMRI-Guided vs. Standard Brain Stimulation for Depression
This study compares two types of repetitive transcranial magnetic stimulation (rTMS) to treat depression. One type uses a brain scan (fMRI) to guide the treatment, while the other uses a standard approach. It may help people whose depression hasn't improved with medication.
Ottawa, OntarioAges 18 years+ - NCT06120374Recruiting
Immunotherapy plus radiation after surgery for upper tract cancer
This trial compares combining immunotherapy with radiation versus standard chemotherapy for patients with high-risk upper urinary tract cancer after surgery. It aims to see if the new combination works better at preventing cancer from coming back.
BeijingAges 18 years+ - NCT06114108Recruiting
Adding local treatment to drug therapy for stage IV lung cancer
This trial compares continuing drug therapy alone versus adding local treatments (surgery or radiation) for people with stage IV lung cancer that has responded to initial treatment but still has a few remaining spots (oligometastatic). The goal is to see if targeting those spots with local therapy helps control the cancer longer.
AarauAges 18 years+ - NCT06128018Recruiting
Endoscopic vs surgical bypass for stomach blockage
This study compares two ways to help with gastric outlet obstruction (a blockage in the stomach or small intestine) caused by a tumor. It tests if a procedure using an endoscope (a long, flexible tube with a camera) is as good as surgery to help you eat and drink more comfortably.
Orlando, FloridaAges 18 years+ - NCT06107673RecruitingPhase 2
Pill vs chemo before breast cancer surgery
This study compares taking a daily pill (dalpiciclib with hormone therapy) versus standard chemotherapy before breast cancer surgery. It's for postmenopausal women with a common type of early breast cancer that is strongly hormone-receptor positive and HER2-negative.
Shijiazhuang, HebeiAges 18–75 - NCT05501262Recruiting
Cryoablation vs steroid injection for Morton’s neuroma pain
This trial compares two ways to treat Morton’s neuroma pain: freezing treatment (cryoablation) versus steroid plus lidocaine injections. It may help people who didn’t improve after trying basic shoe inserts or padding, by seeing which approach works better for symptoms.
Portland, OregonAges 18–105 - NCT05671718Recruiting
Nurse vs doctor treatment for drug-resistant tuberculosis
This trial compares a nurse-led plan versus a physician-led plan for treating new drug-resistant TB patients using an outpatient clinic approach. It may help by showing which care style works best and is safest for patients starting treatment close to home.
Pietermaritzburg, KwaZulu-NatalAges 18 years+ - NCT06091865RecruitingPhase 3
Testing odronextamab with chemo for untreated DLBCL
This trial is testing a new drug called odronextamab combined with chemotherapy against the standard treatment for people with previously untreated DLBCL. The goal is to see if the new combination works better and is safe.
Scottsdale, ArizonaAges 18 years+ - NCT06103864RecruitingPhase 3
Study of Dato-DXd with or without durvalumab for advanced triple-negative breast cancer
This trial is testing whether a new drug combination (Dato-DXd with or without durvalumab) works better than standard chemotherapy plus pembrolizumab for people with a certain type of advanced triple-negative breast cancer that has a protein called PD-L1. The study aims to find a more effective treatment option for this specific group.
Daphne, AlabamaAges 18 years+ - NCT06101745RecruitingPhase 2/Phase 3
Trial to see ureters during abdominal or pelvic surgery
This trial tests a dye called Nizaracianine Triflutate that helps surgeons see the ureters (tubes from kidneys to bladder) during surgery. It aims to make surgery safer by reducing the risk of accidentally injuring the ureters.
Los Angeles, CaliforniaAges 18 years+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,699 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.