Treatment
Diclofenac clinical trials
We’re tracking 20 recruiting studies that include Diclofenac, each written for real people, not researchers, below.
Recruiting studies
- NCT06636227RecruitingPhase 1
Diclofenac dose study for alcohol use disorder
This study tests whether different doses of diclofenac, an anti-inflammatory drug, can help people reduce heavy drinking. It looks at how the drug affects drinking patterns and overall health.
Catonsville, MarylandAges 21–65 - NCT07071441Recruiting
Indomethacin vs Diclofenac before ERCP to prevent pancreatitis
This study compares two common NSAID medications (indomethacin and diclofenac) given before an ERCP procedure to see if one is better at preventing pancreatitis, a common complication. If you are having an ERCP and meet the health criteria, you may be able to join.
Beijing, Beijing MunicipalityAges 18–90 - NCT04050644RecruitingPhase 4
Tested preservative-free vs standard eye drops after cataract surgery
This study compares different anti-inflammatory and pain-relief eye drops after cataract surgery to see which one works better. It focuses on whether preservative-free drops cause fewer problems (like irritation) while still protecting the eye during healing.
Leuven, Vlaams-BrabantAges 60 years+ - NCT05254574RecruitingPhase 1
Acoustic therapy for ongoing joint pain from osteoarthritis
This Phase 1 study tests a sustained acoustic medicine device to help reduce pain from osteoarthritis (wear-and-tear arthritis) in joints like knees or hips. Because it’s early-stage research, you may be asked to follow strict rules about pain medicines and device use while the team monitors safety and comfort.
Tampa, FloridaAges 35–85 - NCT05883241RecruitingPhase 1
Sound-based treatment for fracture pain
This early-stage study tests a device that uses sound to reduce pain from a bone fracture and improve daily quality of life. If you have mild-to-moderate fracture pain and can follow the device routine, you may be able to try this treatment while avoiding other pain medicines and fracture-area therapies.
Trumbull, ConnecticutAges 18–80 - NCT06053411RecruitingEarly Phase 1
How your genes affect the breakdown of diclofenac
This study looks at how a specific gene (UGT2B17) affects how your body processes diclofenac, a common pain reliever. Healthy people aged 18 to 64 are needed to help understand genetic differences in drug metabolism.
Spokane, WashingtonAges 18–65 - NCT06207253RecruitingPhase 2/Phase 3
Testing diclofenac gel for tooth root infections
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
CairoAges 18–50 - NCT06731270RecruitingPhase 2
Diclofenac for advanced lung cancer on immunotherapy
This trial tests whether adding the anti-inflammatory drug diclofenac can help people with advanced non-small cell lung cancer whose tumors are growing while on a single immunotherapy drug. You must have been on immunotherapy for at least 12 weeks and have a growing tumor, but your doctor does not plan to change your treatment right away.
Atlanta, GeorgiaAges 18 years+ - NCT06905561Recruiting
Diclofenac cream to prevent skin irritation from radiation
This trial tests if a diclofenac cream can help prevent skin redness, peeling, or pain caused by radiation therapy. It is for people with certain head and neck cancers or breast cancer who are starting radiation treatment.
Haikou, HainanAges 18–75 - NCT07178639Recruiting
Comparing three eye drops after cataract surgery
This trial tests three different anti-inflammatory eye drops to see which works best for pain and swelling after cataract surgery. You may join if you are scheduled for cataract surgery only, and you can apply the drops yourself or have help.
KolínAges 18 years+ - NCT06829030Enrolling by invitationPhase 1/Phase 2
Comparing two injections for low back pain relief
This trial compares two types of injections—one standard anti-inflammatory drug and one simple sugar water solution—to see which works better for treating low back pain in an emergency setting. If you are an adult between 18 and 55 with isolated low back pain, this study may help find a more effective pain treatment.
AksarayAges 18–55 - NCT06373978RecruitingPhase 4
Non-narcotic pain relief after elbow needle procedure
This study tests non-narcotic pain medicine after a needle procedure for chronic elbow tendon pain. It compares different pain-relief options to find what works best without opioids.
Coral Springs, FloridaAges 18–65 - NCT05816226RecruitingPhase 3
Topical cream for jaw joint pain
This Phase 3 study tests a skin-applied treatment (a cream or gel) to reduce pain in the jaw joint (TMJ). You may benefit if you have TMJ pain and can safely use the study medication without conflicting treatments.
San Francisco, CaliforniaAges 18 years+ - NCT06012097RecruitingPhase 4
Aromatherapy gel for De Quervain's wrist pain
This trial tests if a gel made with essential oils can help reduce pain from De Quervain's disease, a painful wrist condition. If it works, it could be a natural option to relieve discomfort.
StrasbourgAges 18–75 - NCT06158620RecruitingPhase 1/Phase 2
Nasal spray for pain after ureter stent placement
This trial tests whether a nasal spray form of the painkiller ketorolac can safely reduce pain from a ureteral stent after stone surgery. If you are having a ureteroscopy with stent placement, this might help you manage discomfort without stronger medications.
Dallas, TexasAges 18 years+ - NCT06574191Recruiting
Knee osteoarthritis study: pain and health outcomes
This study looks at how knee pain from osteoarthritis affects your daily life and health. You'll use a topical anti-inflammatory gel and answer questions by text or email for two months.
Sacramento, CaliforniaAges 50 years+ - NCT06857110Recruiting
Nerve block vs. hematoma block for wrist fracture pain
This study compares two ways to manage pain when a broken wrist is realigned without surgery: a nerve block near the elbow vs. a numbing injection directly into the fracture. It may help researchers find which method works better and is more comfortable for you.
Bogotá, Bogota D.C.Ages 18 years+ - NCT06937853Recruiting
Genes and painkiller response for tooth pain
This trial tests whether your genes affect how well a common painkiller (NSAID) works for tooth pain after a root canal procedure. It may help find the best pain relief for you.
Erzurum, ErzurumAges 18–65 - NCT07145645RecruitingPhase 3
Comparing topical diclofenac to oral ibuprofen for pain from ankle or knee injuries in children
This study compares a topical gel (diclofenac) applied directly to the injury site versus an oral medication (ibuprofen) taken by mouth to see which works better for treating pain from ankle or knee injuries in children. It may offer a way to relieve pain without a pill.
Calgary, AlbertaAges 6–18 - NCT07237620Recruiting
Comparing medicines for failed root canal treatment
This trial compares different medicines placed inside the tooth after a failed root canal to help heal the infection at the root tip. If you have a back tooth that still has an infection even though it had a root canal years ago, this study may test which medicine works best for you.
Hatay, AntakyaAges 18–60
What Diclofenac is being studied for
Conditions with recruiting Diclofenac studies.
Common questions
- Are there clinical trials studying Diclofenac?
- Yes. Clin2 currently lists 20 recruiting studies that include Diclofenac, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Diclofenac trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Diclofenac an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Diclofenac or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.