CAR T cells targeting mesothelin for solid tumors
Treatments studied
Part of Blood & lymphatic, Cancer, Digestive system, Hormones & metabolism, Lungs & breathing, Women’s health & pregnancy clinical trials.
This study tests a new treatment called CAR T cells that target a protein called mesothelin found on certain cancer cells. The CAR T cells are made from your own immune cells and may help shrink tumors that have not responded to other therapies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of cancer called mesothelioma (with certain cell types) or another solid tumor that makes the mesothelin protein.
- Your cancer has grown after at least one standard treatment, or you have pancreatic cancer and can collect cells before starting treatment.
- You are 18 years or older and in good daily health (ECOG 0 or 1).
- Your blood counts, liver, kidney, and heart function are within study limits.
- You do not have uncontrolled autoimmune disease, lung scarring, or active infections like HIV or hepatitis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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