Ketamine or dexmedetomidine for confusion in heart failure
Treatments studied
Part of Brain & nervous system, Heart & circulation, Mental health clinical trials.
This study tests two medicines given through an IV to treat delirium (confusion or agitation) in people who are in the intensive care unit with acute heart failure. The goal is to see which medicine works better to clear the confusion and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have acute heart failure (a sudden worsening of the heart's ability to pump blood).
- You must be in the ICU with active delirium (confusion or agitation) that is either hyperactive (restless) or hypoactive (very sleepy).
- You must not have certain severe liver or kidney problems (such as very poor kidney function).
- You must not have taken sedatives or antipsychotics in the last 48 hours before the trial starts.
- You must not have a history of psychosis, schizophrenia, or substance abuse disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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