Clinical trials
ACL clinical trials
Below are recruiting acl clinical trials, each written for real people, not researchers. We’re tracking 129 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07762989Recruiting
Ankle recovery after ACL surgery using a leg tendon graft
This study examines how well the ankle and lower leg recover after ACL reconstruction when the graft is taken from the peroneus longus tendon. By participating, you help doctors learn how this procedure affects ankle strength and function, which may improve future care.
Çankaya, AnkaraAges 18–55 - NCT06631690Recruiting
ACL surgery and ankle joint function study
This study looks at how ACL reconstruction knee surgery might affect the mechanics of your ankle joint. It aims to understand if the surgery changes how your ankle moves and works, which could help improve rehabilitation.
CairoAges 15–45 - NCT07674784Recruiting
Boosting quad strength after ACL reconstruction
This study tests ways to improve quadriceps muscle strength in people who had ACL reconstruction surgery within the past 4 months. It examines extra interventions during rehab to help you regain leg strength faster.
Madison, WisconsinAges 18–40 - NCT07671729Recruiting
Comparing two tendon grafts for ACL surgery
This study compares two types of tendon grafts (from your kneecap tendon or from a tendon in your leg) for ACL reconstruction. The goal is to see which one works better for getting you back to normal activity.
Istanbul, BesiktasAges 18–50 - NCT07671235Recruiting
Comparing graft options for repeat ACL surgery
This study compares two types of tissue grafts (your own or a donor's) used in a second ACL knee surgery to see which leads to better outcomes and fewer failures over at least two years.
Bologna, BolognaAges 18–50 - NCT07642752Recruiting
Balance training after ACL surgery
This study compares two types of physical therapy exercises to see which works better for reducing pain, improving movement, balance, and daily function in men who have had ACL surgery. It may help you recover more fully after your knee surgery.
Lahore, Punjab ProvinceAges 18–45 - NCT07636278Recruiting
Augmented Reality guidance for ACL knee surgery
This trial tests whether using augmented reality (special computer graphics overlaid on surgical video) during ACL reconstruction surgery helps surgeons perform the procedure more accurately. You would undergo standard knee surgery, but the surgeon would have real-time computer guidance to assist with precision.
Milan, MichiganAges 18 years+ - NCT06166381Recruiting
Antibiotics in ACL reconstruction: vein vs. vein plus soaked graft
This trial compares two methods for preventing infection during ACL reconstruction surgery. One group gets antibiotics through a vein, and the other group gets antibiotics through the vein plus a special antibiotic-soaked graft placed in the knee.
DuhokAges 20–45 - NCT07507708Recruiting
Smart insulin system with behavior support for type 1 diabetes
This study tests a smart insulin pump and continuous glucose monitor system that adjusts insulin automatically and uses behavior support to improve blood sugar control. It's for people with type 1 diabetes who have used an approved automated insulin delivery system recently and are willing to use study devices.
Charlottesville, VirginiaAges 18 years+ - NCT04770233Recruiting
Comparing early surgery options for torn ACL
This study looks at the best way to treat a fresh ACL (an important knee ligament) tear by comparing an “early surgery” plan that starts within 12 weeks. It may help guide care and recovery for people who are able to do both the surgery and the follow-up rehabilitation.
Lørenskog, AkershusAges 16–50 - NCT06190223Recruiting
ACL repair using kneecap tendon with press-fit method
This study looks at a specific ACL reconstruction technique using a graft from your kneecap tendon that is fixed with a press-fit method. It aims to determine how well patients recover after at least one year.
AnkaraAges 18–55 - NCT05972876Recruiting
Blood-flow restriction rehab after ACL surgery
This trial looks at how well your ACL graft (the repaired tissue) heals after ACL reconstruction when you use a specific rehab method called blood-flow restriction training. It may help your care team understand whether this rehab approach leads to better healing and function.
Sittard, LimburgAges 18–65 - NCT07434726Recruiting
Balloon in aorta to improve CPR for in-hospital cardiac arrest
This trial tests if placing a balloon in the main artery (aorta) during CPR can improve blood flow to the heart and brain. It is for adults who have a cardiac arrest while already in the hospital and have a pulse-check showing some heart activity.
BernAges 18 years+ - NCT07423767Recruiting
Counseling before ACL surgery to reduce fear and improve recovery
This study tests whether a short counseling program before ACL surgery can help reduce fear of movement and improve recovery. If you are preparing for your first ACL reconstruction, this program may help you feel more confident and get back to activities sooner.
Beijing, None SelectedAges 18–45 - NCT07366619Recruiting
MADI ACL study: a new MRI method for ligament repair
This trial tests a new MRI technique called Magic Angle Direction Imaging (MADI) to see if it can give better images of the knee before ligament repair surgery. It may help doctors plan your surgery more accurately.
LondonAges 18–65 - NCT07306221Recruiting
Balance training after ACL surgery using visual guides
This study tests if a special video-based balance training program helps people recover knee function better after ACL reconstruction surgery. It is designed for patients who had surgery within the past year using their own hamstring tendon.
BeijingAges 18–45 - NCT07243535Recruiting
Rhythm training for athletes after ACL surgery
This study compares two types of rhythm-based training (fractal vs isochronous cueing) to see which helps athletes regain better movement after ACL reconstruction. If you're an athlete who had ACL surgery less than two years ago and are now pain-free walking, you may be able to join.
Almada, Monte de CaparicaAges 15–35 - NCT06936995Recruiting
Comparing pain relief methods for ACL surgery recovery
This trial tests two ways to manage pain after ACL reconstruction: a combination of medications (multimodal analgesia) versus a nerve block in the thigh (femoral block). The goal is to see which approach provides better pain control and recovery.
AnkaraAges 18–65 - NCT07174986RecruitingPhase 2/Phase 3
Double defibrillation for out-of-hospital cardiac arrest
This trial tests whether giving two shocks in a row (instead of one) helps restart the heart in people who have a cardiac arrest outside the hospital and need a defibrillator.
AmsterdamAges 18 years+ - NCT07128602Recruiting
Brain stimulation to help quadriceps after ACL surgery
This study tests whether a gentle, non-invasive brain stimulation can improve thigh muscle function in women recovering from ACL reconstruction. If you are between 2 and 6 months post-surgery, you may be able to join.
Glenside, PennsylvaniaAges 18–35 - NCT07043569Recruiting
Strength training with blood flow restriction after ACL surgery
This trial tests a special type of strength training that uses a blood pressure cuff to limit blood flow during exercises. It aims to help people recover muscle strength and improve knee function after ACL surgery.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07041242Recruiting
ACL reconstruction outcomes in older vs. younger adults
This study compares how well a specific type of ACL knee surgery works in people over 50 versus those under 30. It looks at results and problems after surgery to see if the technique is safe and effective for older patients.
Bologna, BolognaAges 18 years+ - NCT07023653Recruiting
ACL repair: comparing all-inside vs. standard tunnel surgery
This study compares two ways of repairing a torn ACL: a newer 'all-inside' method versus a standard tunnel method. It is designed for adults with a simple ACL tear, not for those with multiple ligament injuries, severe cartilage damage, or active infection.
DepokAges 18–65 - NCT06991192Recruiting
ACL surgery rehab with exercise and mental support
This study tests a rehab program that combines physical exercises with psychological support to help young athletes recover from ACL surgery and return to sports safely.
Bloomington, MinnesotaAges 15–25
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Common questions
- Are there clinical trials for acl?
- Yes. Clin2 currently lists 129 recruiting acl studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acl trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acl trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.