Clinical trials
ACL clinical trials
Below are recruiting acl clinical trials, each written for real people, not researchers. We’re tracking 129 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06983184Enrolling by invitation
Period-synced training for teenage athletes
This trial tests a training program that adjusts to your menstrual cycle to help teenage athletes prevent injuries and improve strength. It uses a smart ring to track sleep, activity, and body signals.
Frisco, TexasAges 13–19 - NCT06961292Enrolling by invitation
Knee ligament surgery study for ACL tears with extra rotation
This study compares two surgery techniques for ACL tears where the knee also twists too much inward. It aims to find which method leads to better long-term knee stability.
BeijingAges 18 years+ - NCT06948591Recruiting
BioBrace® Support in ACL Reconstruction Surgery
This study looks at how well a special tissue support called BioBrace® works when used during ACL reconstruction surgery. It follows patients who have already had the surgery or are planning to have it, to see how their knee recovers over time.
New Haven, ConnecticutAges 14–70 - NCT06868147Recruiting
Long-term results of a second ACL reconstruction using a tendon graft
This study looks at people who had a second surgery to fix a torn ACL in their knee. The surgery used a special technique with a tendon from the Achilles. Researchers want to see how well the knee works and looks on X-rays at least 2 years after that surgery.
BolognaAges 18–50 - NCT06818201Recruiting
Brain stimulation for ACL surgery recovery
This study tests if a gentle, noninvasive brain stimulation called tDCS can improve how your brain controls leg muscles and speeds up recovery after ACL surgery.
Valencia, ValenciaAges 16–40 - NCT06793033Recruiting
A study of the Neurescue device for cardiac arrest
This trial tests an investigational device called Neurescue, used alongside standard CPR and life support to treat adults who have had a witnessed cardiac arrest. It is designed for people whose heart cannot be restarted by a shock and who receive CPR very soon after collapse.
BerlinAges 18–80 - NCT06798623RecruitingPhase 1
ACL repair with stem cells from your own knee fat
This trial tests whether adding stem cells from your knee fat pad to a standard ACL reconstruction helps you heal better. It is for Houston Methodist patients who can do physical therapy there and meet basic health requirements.
Houston, TexasAges 18 years+ - NCT06688344Recruiting
Shock wave therapy after ACL surgery
This trial tests if adding focused shock wave therapy to standard rehab can improve recovery after ACL reconstruction using a hamstring graft. It may help reduce pain and speed up healing.
IstanbulAges 18–45 - NCT06686680Recruiting
Shockwave therapy for knee arthritis after ACL repair
This study tests whether shockwave therapy can help knee pain and function in people who developed knee osteoarthritis after an ACL reconstruction. If you had ACL surgery at least a year ago and still have knee pain, this treatment might offer a new option without surgery.
Cambridge, MassachusettsAges 18–55 - NCT06668376Enrolling by invitation
Incrediwear recovery products after ACL repair surgery
This study is testing Incrediwear recovery products (like sleeves or wraps) to see if they help reduce pain and swelling and improve healing after ACL repair. If you're having ACL surgery and meet the health requirements, you may be able to join.
Denton, TexasAges 18–65 - NCT06596824Recruiting
Digital training to reduce inflammation after ACL knee surgery
This trial tests a personalized digital training program for people who recently had ACL knee surgery. The goal is to see if correcting movement patterns can lower inflammation and prevent early knee arthritis.
BerlinAges 18–50 - NCT06561035Enrolling by invitationPhase 3
Opioid-sparing study for ACL reconstruction
This study tests pain management options after ACL reconstruction to reduce the need for strong painkillers. It may help you recover with fewer side effects and lower risk of opioid dependence.
Skokie, IllinoisAges 14–85 - NCT06456268Recruiting
VibraCool to reduce pain and opioid use after ACL surgery
This trial tests a device called VibraCool to see if it can reduce pain and the need for opioid painkillers after ACL reconstruction surgery.
New York, New YorkAges Any age - NCT06382324Recruiting
Mindfulness for knee recovery after ACL surgery
This study tests whether practicing mindfulness within the first month after ACL (anterior cruciate ligament) surgery can help with your mental well-being during recovery. You'll learn techniques to stay calm and focused.
Keelung, TaiwanAges Any age - NCT06240780Enrolling by invitation
Incrediwear recovery study for ACL and MCL surgery
This trial tests whether wearing Incrediwear clothing helps you recover faster after arthroscopic knee surgery for ACL or MCL tears. It is designed for people about to have surgery and who want to improve their healing process.
Oklahoma City, OklahomaAges 18–65 - NCT04408885Recruiting
Rehab program for a torn ACL ligament
This study looks at a rehabilitation-focused treatment plan after an ACL (an important knee ligament) tear. It may help you by testing the best rehab approach for improving knee function and stability.
Aarhus NAges 18–50 - NCT06189573Enrolling by invitation
ACL repair: quadriceps vs patellar tendon graft
This trial compares two ways to rebuild a torn ACL using either a piece of your quadriceps tendon (with a small bone piece) or a piece of your patellar tendon (with bone). The goal is to find which graft works best for long-term stability and recovery.
Mexico City, Mexico CityAges 15–55 - NCT05949177Recruiting
Mindfulness and graded exercise for fear after ACL surgery
This trial studies whether a combination of mindfulness practice and a step-by-step return-to-activity plan can reduce fear and improve recovery after ACL reconstruction. It may help people who feel worried about re-injury and want a structured way to get back to sports.
Chapel Hill, North CarolinaAges 14–35 - NCT06041763Recruiting
Bridge-enhanced ACL repair for meniscus repair
This study tests a special bridge implant to help heal a torn meniscus during surgery. It may help improve recovery and reduce the need for additional surgeries.
New York, New YorkAges 18–75 - NCT05754632Recruiting
Blood flow restriction exercises after ACL surgery in teens
This trial tests whether a special type of exercise that uses a cuff (blood flow restriction training, or BFRT) can help teens recover after ACL reconstruction. It’s designed to see if adding BFRT to standard rehab improves strength and return to sport.
Farmington, ConnecticutAges 12–18 - NCT05527548RecruitingPhase 4
Alendronate for knee recovery after ACL surgery
This trial tests whether alendronate, a drug commonly used for bone health, can improve knee function and recovery after ACL surgery. It is for people having their first ACL repair.
ShatinAges 14 years+ - NCT05527171Recruiting
Virtual reality mindfulness after ACL knee surgery
This study uses a virtual-reality mindfulness meditation program to help improve fear and movement quality after ACL reconstruction. It may help you feel less afraid of movement and land more safely when you return to sports.
Chapel Hill, North CarolinaAges 14–25 - NCT05461326Recruiting
Compare two tendon grafts for ACL surgery recovery
This study compares two ways to rebuild the ACL using different tendon grafts (quadriceps tendon vs patellar tendon) taken from your own body. It aims to learn which option leads to better recovery after ACL reconstruction, including strength and function.
Birmingham, AlabamaAges 14–65 - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+
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Common questions
- Are there clinical trials for acl?
- Yes. Clin2 currently lists 129 recruiting acl studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acl trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acl trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.