Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 447 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07624396Recruiting
Brain protein levels and heart-related strokes
This study looks at a brain protein called BDNF in people who've had a stroke caused by a clot from the heart. Researchers want to understand if BDNF levels can help explain why some strokes happen this way and may help doctors prevent future strokes.
DijonAges 18 years+ - NCT03720522Recruiting
Study brain-heart signals in acute stroke using MRI
This study looks at how the brain and heart interact right after an acute ischemic stroke. It may help doctors better understand what happens in the first hours of stroke and improve monitoring or future treatments.
Bern, Canton of BernAges 18–86 - NCT07606807RecruitingPhase 3
New clot-busting medication for stroke in the extended time window
This trial tests a new medication called rhTNK-tPA for treating acute ischemic stroke (a clot in the brain) up to 24 hours after symptom onset. The study uses simplified imaging to determine eligibility and aims to help patients recover better outcomes.
GuangzhouAges 18 years+ - NCT06211712Recruiting
Drug plus clot removal for large vessel stroke
This study tests whether adding a drug called human urinary kallidinogenase to standard clot-removal therapy helps people recover better after a large-vessel stroke. If you qualify, you would receive the drug or a placebo by IV along with the procedure, and doctors will monitor your recovery.
ShanghaiAges 18 years+ - NCT07599904Recruiting
Real-world study of Medtronic stroke treatment devices
This registry tracks how Medtronic's FDA-approved devices work in treating acute ischemic stroke (a type of stroke caused by a blood clot) in everyday clinical practice. Researchers collect information to understand device safety and effectiveness outside of formal clinical trials.
Flint, MichiganAges 18 years+ - NCT07581210RecruitingPhase 2
QD202 Study for Recent Stroke Treated With Clot-Busting Medicine
This study tests whether a new drug called QD202 can help protect the brain and improve recovery when given alongside standard clot-busting therapy (thrombolysis) for acute ischemic stroke. You would be in the trial if you had a stroke in the last 24 hours and are receiving or planning to receive thrombolytic treatment.
Meizhou, GuangdongAges 18–85 - NCT07575984RecruitingPhase 4
Mexidol Safety and Efficacy for Acute Ischemic Stroke
This trial tests whether Mexidol, a medication that may protect brain tissue, can help people recover better after an acute ischemic stroke (a type of stroke caused by a blood clot). The study includes stroke patients and healthy volunteers to understand how the drug works and if it's safe.
ArkhangelskAges 18–90 - NCT03356392Recruiting
Registry for stroke patients getting clot-busting treatment
This study records information from adults with an acute ischemic stroke (a stroke caused by a blocked artery) who receive clot-busting medicine within 4.5 hours. It may help doctors better understand which patients benefit from treatment and how care decisions are made for certain blocked brain arteries.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07556068Recruiting
Brain Blood Flow Recovery After Stroke Clot Removal
This study enrolls people who had an acute ischemic stroke (caused by a blood clot) and received emergency treatment to remove the clot. Researchers want to understand why some patients recover well while others don't, by measuring how the brain regulates its own blood flow after treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06741332Recruiting
AI software to speed up stroke clot removal referrals
This trial tests whether a special AI software can help doctors speed up the process of referring patients with acute stroke for a procedure that removes a blood clot (thrombectomy). If you have stroke symptoms and a recent CT scan, the AI may help identify if you could benefit from this treatment.
Granollers, BarcelonaAges 18 years+ - NCT07550296RecruitingPhase 2
Second IV Clot-Dissolving Treatment for Major Stroke
This trial tests giving a second dose of an IV clot-dissolving medicine (prourokinase) to patients who had a stroke from a large clot but didn't improve enough after the first dose. The goal is to see if a second dose within 6 hours of stroke onset can help more patients recover.
Shenyang, None SelectedAges 18–80 - NCT07540741Recruiting
PCSK9 Inhibitors for Large-Artery Stroke Recovery
This trial tests whether a cholesterol-lowering medication called evolocumab (a PCSK9 inhibitor) can help people recover better after a specific type of stroke caused by clogged arteries. The study checks if lowering cholesterol further than usual statins do improves stroke outcomes and is safe.
HeilongjiangAges 18–80 - NCT06753006Recruiting
Research on stroke rehabilitation for arm weakness
This study tests a new rehabilitation program for people who have had a stroke within the last 6 months. It focuses on improving arm weakness using special therapy techniques.
Samara, Samara OblastAges 18–80 - NCT07519044RecruitingPhase 4
GM1 drug added to clot removal for acute stroke
This study tests whether adding a medicine called GM1 to emergency clot-removal surgery helps people recover better from sudden strokes caused by blood clots in major brain arteries. GM1 may protect brain cells from damage during and after the stroke.
Beijing, Beijing MunicipalityAges 18–80 - NCT06301412RecruitingPhase 3
Cooling plus clot removal for acute stroke
This trial tests whether cooling the body down (hypothermia) combined with a clot removal procedure (thrombectomy) helps people recover better from a large-artery stroke. You may be eligible if you have a moderate-to-severe stroke and can be treated within 24 hours of when you were last seen well.
Freiburg im BreisgauAges 18 years+ - NCT06059144RecruitingPhase 3
Raising blood pressure for worsening small artery strokes
This trial tests if raising blood pressure slightly with a low dose of a medicine called norepinephrine can help people whose stroke symptoms are getting worse. It focuses on small, deep brain artery strokes and aims to improve recovery.
BordeauxAges 18 years+ - NCT07491744Enrolling by invitation
Stroke and TIA study on heart and blood vessel health
This study looks at the causes of stroke and TIA by doing extra tests on patients admitted to the hospital. It aims to better understand and prevent future heart and blood vessel problems.
Stockholm, Stockholm CountyAges 18 years+ - NCT07491952Recruiting
Continuous Dual Aspiration for Stroke With Zoom System
This trial tests a new way to remove blood clots from the brain using the Zoom System with a continuous double-suction technique (CDAT). It aims to see how well this approach works for people having a stroke caused by a large vessel blockage.
Huntsville, AlabamaAges 18 years+ - NCT04956185Recruiting
Collecting hospital data from people with stroke
This study collects information from people admitted to the stroke care team or neurology during their hospital stay. It may help improve stroke care by understanding patient conditions and hospital experiences.
Ghent, FlandersAges Any age - NCT07475936Recruiting
Tenecteplase for very old patients with stroke
This trial tests if a clot-busting drug called tenecteplase is safe and effective for people over 80 who have an ischemic stroke and can get treatment within 4.5 hours of symptoms starting.
Nanning, GuangxiAges 80 years+ - NCT07475949RecruitingPhase 3
Stroke treatment for unknown wake-up time
This trial tests a clot-busting drug for people who had a stroke but don't know when it started, like waking up with symptoms. It may help reduce disability if given soon after noticing symptoms.
Xiamen, FujianAges 18 years+ - NCT05864638Recruiting
Registry study of clot-removal treatment for acute stroke
This study records outcomes for people having an acute ischemic stroke treated with an endovascular (catheter-based) procedure. It may help doctors understand how clot-removal treatment works in different patients and hospitals.
ShanghaiAges Any age - NCT06374667Recruiting
Skull bone injection vs. IV for large stroke
This trial tests a new way to give medicine for a large stroke on one side of the brain. The medicine is injected into the skull bone instead of through a vein, and researchers want to see if it works better and is safe.
Wuhu, AnhuiAges 18–80 - NCT06585228Recruiting
Heart CT vs ultrasound to find clots after stroke
This study compares two ways to look for blood clots in the heart after a stroke: a heart CT scan and an ultrasound done through the food pipe. It aims to see if the CT scan can spot clots just as well as the more invasive ultrasound.
Amsterdam, North HollandAges 18 years+
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 447 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.