Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 458 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05247125RecruitingPhase 4
Testing light or melatonin to help brain recovery after stroke
This study looks at whether changing your sleep timing using light therapy or melatonin can improve “brain rewiring” after an ischemic stroke. It mainly focuses on people who arrive very soon after stroke symptoms and who also meet specific safety and sleep/medication requirements.
Saint PetersburgAges 18–80 - NCT05281055Recruiting
Registry of clot-removal treatment for sudden large-vessel strokes
This study keeps a record of people treated with a clot-removal procedure (endovascular thrombectomy) for a sudden stroke caused by a blocked large blood vessel in the brain. It focuses on outcomes for patients who can be treated within 24 hours and were independent before the stroke.
TaipeiAges 20 years+ - NCT05293080RecruitingPhase 3
Early heart rhythm treatment to help prevent stroke
This trial tests an early treatment approach for people who had a recent ischemic stroke (a stroke caused by a blocked blood vessel) and have an irregular heart rhythm called atrial fibrillation (AF). It aims to lower the chance of having another stroke by treating AF as early as possible after the stroke.
HamburgAges 18 years+ - NCT05300997Recruiting
Test blood and antibody markers for suspected acute stroke
This study looks at blood tests to find signs of immune activity after a suspected stroke. It may help doctors diagnose stroke faster and better understand what is happening in the body soon after symptoms start.
Hong KongAges 18–100 - NCT05363397RecruitingPhase 2
Adjunctive TBO-309 added to stroke clot removal treatment safety
This Phase 2 trial studies whether adding TBO-309 to standard emergency treatment for acute ischemic stroke is safe and tolerable. It may help researchers see if the added drug can be given without causing excessive side effects alongside clot-busting and/or clot-removal procedures.
Camperdown, New South WalesAges 18 years+ - NCT05378490Recruiting
Study of stroke types and thrombolysis treatment
This study includes people who have had certain kinds of sudden brain blood-flow problems (like an ischemic stroke, bleeding in the brain, or a brief warning episode) or conditions that look similar. It looks at how treatment such as clot-busting medicine (thrombolysis) fits for these situations.
LørenskogAges 18 years+ - NCT05410457Recruiting
Study different treatments after ischemic stroke
This trial looks at which treatment approach after an ischemic stroke (a stroke caused by a blocked blood vessel) may lead to better outcomes. It may help doctors better choose treatments that improve recovery and prognosis.
Nanjing, JiangsuAges 18 years+ - NCT05424978Recruiting
Standardized green-channel treatment for acute stroke care
This study tests a structured, fast way of treating people who have a new ischemic stroke (a stroke caused by a blocked blood vessel). It may help because it focuses on getting the right stroke treatments quickly and consistently.
Xi'an, ShaanxiAges 18–100 - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT05494034Recruiting
Monitoring heart rhythms after stroke to guide care
This study uses a small implantable heart monitor to track heart rhythm in people after an acute ischemic stroke or TIA. It aims to learn how often hidden heart rhythm problems show up, which could help doctors choose better stroke prevention treatments.
AthensAges 40–100 - NCT05518305Recruiting
Predicting recurrent stroke risk in people with artery narrowing
This study looks at blood markers and brain/artery scan results to predict who with intracranial artery narrowing is more likely to have another stroke. It may help doctors spot higher-risk people earlier and better target prevention.
Los Angeles, CaliforniaAges 30 years+ - NCT05561088Recruiting
Head acupuncture after stroke clot removal
This trial studies whether doing head acupuncture after a procedure to remove a stroke-causing blood clot can improve recovery and safety. You may be considered if you had endovascular clot removal within 24 hours and meet specific brain-scan and stroke-severity measures.
Xi'an, ShaanxiAges 18–100 - NCT05578300Recruiting
Translating thrombectomy care into real-world practice in Asia-Pacific
This study aims to help endovascular thrombectomy for certain severe strokes work well in everyday hospital care across Asia-Pacific. You may be considered if you’re an adult with a specific type of stroke blocked in a major brain blood vessel.
Linyi, ShandongAges 18 years+ - NCT05600374Recruiting
Brain stimulation timed to brain rhythms after recent stroke
This trial tests a special brain-stimulation approach that targets your brain’s natural 8–12 Hz rhythm to improve arm and hand recovery after stroke. It’s designed for people in the early days after an ischemic stroke, when motor recovery is still changing quickly.
Frankfurt a.M., Frankfurt a.M.Ages 18 years+ - NCT05604638RecruitingPhase 3
Tirofiban soon after tenecteplase for acute stroke flare
This trial tests whether starting tirofiban soon after tenecteplase can improve outcomes for people whose stroke symptoms temporarily get worse after treatment. It aims to see if the added medicine can reduce harmful clot-related changes after initial thrombolysis.
Chuzhou, AnhuiAges 18 years+ - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Mobile, AlabamaAges 18–79 - NCT05626296Recruiting
Blood-sample study of stroke patterns using multiple tests
This study looks at blood and lab “molecular” patterns in people who have had an ischemic stroke (a blocked blood vessel). It aims to understand differences between people labeled as having “phlegm-heat syndrome” versus not, which may help future stroke care. You may be eligible if your stroke was recent and confirmed by MRI.
Beijing, Beijing MunicipalityAges 50–80 - NCT05630586RecruitingPhase 2
Semaglutide shot for early stroke recovery
This Phase 2 study tests whether a semaglutide injection given under the skin soon after an acute ischemic stroke can improve recovery. It may help reduce disability, especially if treatment starts within about 4.5 hours of symptom onset.
AarhusAges 18 years+ - NCT05659160Recruiting
Triage approach for certain strokes from blocked large brain arteries
This trial studies a way to sort and treat people with a specific type of acute ischemic stroke (caused by a blockage in a large brain artery). It may help doctors choose the best next steps—either a procedure or medication—faster and more appropriately.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05686642RecruitingPhase 2
Drug LT3001 for sudden stroke symptoms within 24 hours
This Phase 2 study tests LT3001 to improve recovery after an acute ischemic stroke (a stroke caused by blocked blood flow). It is designed for people who can be treated within 24 hours of symptom onset and who meet specific safety and health requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT05691244RecruitingPhase 3
Tested drug for acute ischemic stroke within 24 hours
This Phase 3 trial studies sovateltide (and a placebo) in adults with an ischemic stroke, aiming to improve safety and outcomes. It focuses on people who can start treatment quickly after stroke symptoms begin and who do not have bleeding in the brain on imaging.
Tucson, ArizonaAges 18–80 - NCT05728333RecruitingPhase 2/Phase 3
Tirofiban or alteplase before clot removal in stroke
This trial tests whether giving either tirofiban or alteplase through a vein before a mechanical clot-removal procedure works better for an acute ischemic stroke. It may help improve how well blood flow returns and how much recovery patients can have after treatment.
Hangzhou, ZhejiangAges 18 years+ - NCT05741905Recruiting
Levofloxacin antibiotic with IV clot-busting for acute stroke
This trial tests whether adding the antibiotic levofloxacin to standard IV clot-busting treatment is safe and improves outcomes after an acute ischemic stroke. It may help by reducing complications related to infection or inflammation, but you must meet specific heart, liver, kidney, and medication-safety rules.
Changchun, JilinAges 18–75 - NCT05756257Recruiting
MRI study of blood pressure swings after ischemic stroke
This trial looks at whether changes in blood pressure after an ischemic stroke (a stroke caused by blocked blood flow) are linked to recovery and outcomes. You may be asked to have MRI scans soon after arriving to help researchers understand who is at higher risk and why.
New Haven, ConnecticutAges 18 years+
Hear when a new Acute Ischemic Stroke trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 458 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.