Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 458 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06374667Recruiting
Skull bone injection vs. IV for large stroke
This trial tests a new way to give medicine for a large stroke on one side of the brain. The medicine is injected into the skull bone instead of through a vein, and researchers want to see if it works better and is safe.
Wuhu, AnhuiAges 18–80 - NCT06388148Recruiting
Clot removal for very large strokes
This trial tests a procedure to remove a large blood clot in the brain (mechanical thrombectomy) for people who have a very large stroke. It aims to see if removing the clot can improve recovery, even for those with severe strokes.
Hengyang, HunanAges 18 years+ - NCT06394180Recruiting
Study of perforations during clot removal for stroke
This trial looks at what happens when a hole (perforation) occurs in a brain artery during clot removal for stroke. It compares patients who had this complication to those who did not, to understand how to better manage it.
BaselAges 18 years+ - NCT06403267RecruitingPhase 2
Testing NoNO-42 for moderate to severe ischemic stroke
This study tests a new drug called NoNO-42 for people having a moderate to severe ischemic stroke. You can join if you get clot-busting medicine within 4.5 hours of your stroke and may also have a procedure to remove the clot.
Calgary, AlbertaAges 18–90 - NCT06418698Recruiting
Brain artery calcium and clot removal outcomes
This study looks at whether calcium buildup in brain arteries affects how well clot removal (mechanical thrombectomy) works for stroke patients. You may be able to join if you have a large artery blockage, a CT scan was done, and you are having the clot removal procedure.
Guangzhou, GuangdongAges 18 years+ - NCT06437600Recruiting
Immediate balloon angioplasty for severe stroke with brain artery narrowing
This trial tests whether doing an angioplasty (a procedure to open a narrowed artery with a small balloon) as soon as possible after a severe stroke caused by a blockage in a brain artery can improve recovery. It is for people who arrive within 24 hours of their stroke and have a specific type of narrowing inside the skull.
Guangzhou, GuangdongAges 18 years+ - NCT06440707RecruitingPhase 2
Brain stimulation for recent stroke recovery
This trial tests a safe, non-invasive brain stimulation technique called tDCS to help people recover from a recent stroke. It's for people who cannot have the standard clot-removal procedure and who can start treatment within 24 hours of their stroke.
Los Angeles, CaliforniaAges 18 years+ - NCT06456437Recruiting
Testing a new technique after clot removal for stroke
This trial tests if a special technique called 'ischemic post-conditioning' can improve recovery after a large vessel stroke. It is for people who have had a major blockage in a brain artery that was successfully opened with a clot retrieval procedure.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06457217Recruiting
MRSI for minor stroke with large artery blockage
This study uses a special MRI technique (called MRSI) to look at brain chemistry in people who have had a minor stroke due to a blocked large artery. The goal is to see if the scan can help doctors better understand the stroke and guide treatment decisions.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT06472336Recruiting
Stenting for severe stroke caused by plaque buildup
This trial tests whether placing a stent (a tiny tube) in the blocked artery in the brain can improve blood flow and help people recover from a severe stroke, especially when standard clot removal has not worked.
Basel, Canton of Basel-CityAges 18 years+ - NCT06474507Recruiting
Calculus Bovis Sativus for Stroke Recovery
This study tests an investigational traditional Chinese medicine called Calculus Bovis Sativus (CBS) for people who have had an ischemic stroke or have small vessel disease in the brain. It aims to see if CBS can help recovery and is safe to use.
Wuhan, HubeiAges 18 years+ - NCT07693816Recruiting
Finding stroke caused by small artery disease
This study looks at whether your stroke was caused by branch atheromatous disease (BAD), a type of small artery blockage. Knowing this may help choose the best treatment and prevention plan.
BeijingAges 18–80 - NCT06492265RecruitingPhase 2
Emergency stroke unit study for acute brain attacks
This trial tests a special stroke unit for people having a severe ischemic stroke (a blood clot in the brain). It aims to see if treatment within 4.5 to 6 hours after symptoms start can improve recovery. You may join if you need a procedure to remove the clot.
BeijingAges 18 years+ - NCT06494436Recruiting
Real-world study of MicroVention devices for aneurysms or stroke
This study collects information from routine medical care to learn how well MicroVention devices work in real-world settings for people being treated for brain aneurysms or stroke from a blocked artery. Your doctor has already decided to use one of these devices as part of your standard treatment.
Vigo, PontevedraAges Any age - NCT06511089RecruitingPhase 3
Carotid artery stenting during stroke clot removal
This trial tests whether placing a stent in a narrowed carotid artery during a procedure to remove a stroke clot improves outcomes. If you have a stroke with a blocked large artery and significant carotid narrowing, this study may be relevant to you.
GroningenAges 18 years+ - NCT06514976Recruiting
Study of Cytoflavin for ischemic stroke without clot treatment
This study is testing a medicine called Cytoflavin for people who have had a recent ischemic stroke but are not receiving clot-busting treatment. It aims to see if Cytoflavin helps improve recovery compared to other treatments or no treatment.
IvanovoAges 18 years+ - NCT06522282RecruitingPhase 3
Testing Emergency Stroke Unit for Acute Stroke (4.5-6 hours)
This trial tests a new way to treat ischemic stroke patients who arrive at the hospital 4.5 to 6 hours after symptoms start. It focuses on people eligible for a clot removal procedure, using advanced imaging to see if this approach helps them recover better.
BeijingAges 18 years+ - NCT06548269Recruiting
Assessing stroke recovery in patients with atrial fibrillation
This study watches how people recover from a recent stroke caused by a heart rhythm problem called atrial fibrillation (or AFib). It aims to find better ways to predict recovery and guide future care.
Jinan, ShandongAges 18 years+ - NCT06548971RecruitingPhase 3
Early antiplatelet after clot-busting for stroke (TREND-IVT)
This trial tests whether giving an antiplatelet medicine (like aspirin) early—within 3 hours of a clot-busting drug—can help prevent another stroke without causing bleeding. It is for people who still have moderate to severe stroke symptoms after the clot-buster and do not have a large artery blockage.
Bengbu, AnhuiAges 18 years+ - NCT06559241RecruitingPhase 3
Arm or leg cuff treatment for large clot stroke recovery
This trial tests whether a simple, non-invasive treatment (repeated inflation of a blood pressure cuff on your arm or leg) can help people recover better after a stroke caused by a large clot. You must be having a mechanical thrombectomy (clot removal) within 24 hours of your stroke.
Suzhou, AnhuiAges 18 years+ - NCT06559436Recruiting
Extending window for clot-busting drug in medium vessel stroke
This trial tests a clot-dissolving drug called tenecteplase given 4.5 to 24 hours after a stroke caused by a blockage in a medium-sized brain artery. It aims to see if waiting longer than usual still helps reduce disability.
Hefei, AnhuiAges 18 years+ - NCT06561867RecruitingPhase 3
Comparing two drugs to prevent another stroke
This trial tests if ticagrelor or cilostazol is better at preventing a second stroke in people who have had their first mild to moderate ischemic stroke. It aims to find which treatment works best within the first 24 hours of symptoms.
Kafr ash ShaykhAges 18–75 - NCT06575140Recruiting
Stroke recovery arm stimulation study
This study tests a noninvasive stimulation technique to help improve arm movement in people who recently had a stroke. It is for those who still have some ability to move their fingers but have significant weakness on one side.
Mexico CityAges 18–79 - NCT06584565Recruiting
Predicting stroke recovery and risk using blood and stool tests
This study uses advanced analysis of your blood and stool samples to better predict how you will recover from a stroke and whether it might happen again. It aims to help doctors personalize your care after a stroke.
Guangzhou, GuangdongAges 18–75
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 458 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.