Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 447 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07026318Recruiting
Combining clot removal and tirofiban for stroke
This trial tests adding the anti-clotting drug tirofiban to standard clot removal for people who have a stroke due to a narrowed artery in the brain. The goal is to see if this combination improves outcomes without raising bleeding risk.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07003386RecruitingPhase 2/Phase 3
Galantamine for recent ischemic stroke
This trial tests a plant-based medicine called galantamine, given within 3 days of an ischemic stroke, to see if it helps recovery. It combines Western and Traditional Chinese Medicine approaches and aims to understand how the treatment works.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06995625RecruitingPhase 1
Stem cell particles for recent stroke recovery
This trial tests whether stem cell-derived extracellular vesicles can help people recover after a moderate to severe stroke. You may join if you had a stroke in the last 5 days and still have arm or leg weakness, even after standard treatments like clot-busting drugs or clot removal.
Suwon, Gyeonggi-doAges 19 years+ - NCT07001267Recruiting
Comparing two anesthetics for stroke procedure recovery
This trial tests whether a sedative given through an IV or a gas you breathe affects recovery after surgery to remove a blood clot in the brain. It may help find the best way to keep you comfortable during the procedure to improve how well you do after three months.
Kansas City, KansasAges 18 years+ - NCT06994975RecruitingPhase 3
Stroke drug test for patients who missed the 4.5 hour window
This trial tests a clot-busting drug for people who had a stroke more than 4.5 hours ago. It uses a special CT scan to see if the treatment can still help them.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05179473Recruiting
Predict and diagnose stiffness after a recent stroke
This study looks at how to predict and measure spasticity (muscle stiffness and tightness) in people after a recent stroke. It may help clinicians better diagnose and understand what to expect as you recover.
Montreal, QuebecAges 18–85 - NCT06768138RecruitingPhase 3
Giving clot-busting medicine directly into the brain after successful blood flow restoration
This trial tests whether a clot-busting drug given directly into the brain artery can improve recovery after a major stroke caused by a blockage in the front part of the brain. The study is for people whose blood flow has already been successfully restored with standard treatments.
NancyAges 18 years+ - NCT06975696Recruiting
Fusion imaging for stroke clot removal
This trial tests a new imaging technique to help doctors see blood clots more clearly during a procedure to remove them from the brain. It may help patients having a stroke who are already eligible for clot removal.
HelsinkiAges 18 years+ - NCT06956521RecruitingPhase 1
Magnesium during clot removal for severe stroke
This trial tests whether giving magnesium directly into the artery during mechanical thrombectomy (a procedure to remove a blood clot from the brain) improves recovery after a severe ischemic stroke. Magnesium may help protect brain cells from further damage after the clot is removed.
Houston, TexasAges 21–95 - NCT06961487Enrolling by invitation
Stroke treatment trial for large area brain damage
This trial tests if a procedure to remove a large blood clot from the brain (called a thrombectomy) can help people with severe strokes who have a large damaged area. It is for people who can be treated within 24 hours of their stroke starting.
Palo Alto, CaliforniaAges 18–90 - NCT06931535Recruiting
Arm cuff treatment for recent moderate back-of-brain stroke
This trial tests whether a simple, non-drug treatment (using a blood pressure cuff to briefly restrict blood flow to your arm) can help people with a recent moderate stroke in the back part of the brain. It aims to improve recovery by preparing the body to better handle the stroke damage.
ShenyangAges 18 years+ - NCT06881420Recruiting
New stroke treatment study for blocked arteries
This study tests a special technique called BASIS to treat strokes caused by a buildup of plaque in the brain's large arteries. It may help people who have had a stroke from this condition and are treated within 72 hours.
Fuzhou, FujianAges 18 years+ - NCT06878066RecruitingPhase 3
Clot-busting treatment after stroke while on Factor Xa inhibitor
This trial tests a clot-busting drug (thrombolysis) for people who had a stroke while on a Factor Xa inhibitor blood thinner. It aims to see if the drug can still safely break up the clot and reduce disability.
Aalborg, AalborgAges 18 years+ - NCT06848894Enrolling by invitation
Study of a drug for stroke patients after blood clot treatment
This trial tests if adding a drug called human urinary kallidinogenase (HUK) can improve recovery for people who have had a stroke and already received clot-busting medicine or a procedure to remove the clot. The goal is to see if it helps reduce disability after a stroke.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06857487RecruitingPhase 1/Phase 2
Testing an herb formula to prevent early stroke worsening
This study tests a traditional Chinese herb formula called Qingre Huatan to see if it can stop stroke symptoms from getting worse in the first few days. It is for people who have had an ischemic stroke within the last 48 hours and are at high risk for early decline.
Beijing, Beijing MunicipalityAges 18–80 - NCT06853535RecruitingPhase 3
Personalized antiplatelet therapy after stroke or TIA
This study tests whether guiding antiplatelet medication with a blood test can help prevent another stroke or TIA. It looks at people who have had a mild stroke or high-risk TIA within the last 48 hours.
Chengdu, SichuanAges 18 years+ - NCT06828679Recruiting
AI system to improve arm recovery after stroke
This trial tests whether an AI-powered system can help improve arm movement in people who had a stroke 1 to 6 months ago. It uses electrical stimulation to activate muscles and may lead to better recovery.
Hong Kong, Sha TinAges 65–80 - NCT06403267RecruitingPhase 2
Testing NoNO-42 for moderate to severe ischemic stroke
This study tests a new drug called NoNO-42 for people having a moderate to severe ischemic stroke. You can join if you get clot-busting medicine within 4.5 hours of your stroke and may also have a procedure to remove the clot.
Calgary, AlbertaAges 18–90 - NCT06712004RecruitingPhase 2
Testing a new stroke drug: different doses for people who cannot get standard care
This trial tests a new medication (bevifibatide) to see which dose works best for people having an ischemic stroke who cannot get standard treatments like clot-busting drugs or a procedure to remove the clot. It aims to improve recovery by stopping clots from getting worse.
Guangzhou, GuangdongAges 18–80 - NCT06783049Recruiting
Smartphone help to prevent another stroke after recent stroke or TIA
This trial tests a smartphone-based system that helps people who recently had a stroke or TIA manage their risk factors like high blood pressure or diabetes after leaving the hospital. It's designed to see if this tool can prevent another stroke.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06157502RecruitingPhase 3
Shuxuening with clot-busting treatment for ischemic stroke
This trial tests if adding the herbal injection Shuxuening to standard clot-busting treatment improves recovery for people having an ischemic stroke. It is for adults within 6 hours of symptom onset who are already receiving a clot-dissolving medication.
Beijing, Beijing MunicipalityAges 18–100 - NCT06781385Enrolling by invitationPhase 2
Tenecteplase after clot removal for severe stroke
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
Charlotte, North CarolinaAges 18 years+ - NCT06775782Recruiting
Remote conditioning for moderate stroke from large artery blockage
This trial tests whether a non-invasive arm cuff treatment (remote ischemic conditioning) can help people recover from a moderate stroke caused by a blockage in a major artery. You must start the treatment within 48 hours of your first symptoms.
Xi'an, ShaanxiAges 18–85 - NCT06761183RecruitingEarly Phase 1
Gene therapy for arm and leg weakness after stroke
This trial tests a new gene therapy called NXL-001 for people who still have moderate to severe arm or leg weakness 2 to 12 months after a stroke. The treatment aims to help the brain repair itself and improve movement.
Beijing, Beijing MunicipalityAges 40–75
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 447 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.