Clinical trials
Acute Kidney Injury clinical trials
Below are recruiting acute kidney injury clinical trials, each written for real people, not researchers. We’re tracking 199 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04705766Recruiting
Study kidney injury after recent COVID infection
This study looks at how COVID can affect the kidneys soon after infection. You may be able to participate if you recently tested positive for COVID and have not had kidney replacement treatments.
San Francisco, CaliforniaAges 18 years+ - NCT04722939Recruiting
Testing brain function outcomes after ICU kidney failure treatment
This trial studies how treating severe kidney injury in the ICU may affect patients’ brain and thinking function over time. It compares measurements of brain activity and function after starting kidney replacement therapy.
Kingston, OntarioAges 18 years+ - NCT04750616RecruitingPhase 2
NAD+ for heart injury prevention around non-emergency surgery
This Phase 2 trial studies whether adding NAD+ can reduce heart muscle injury around scheduled heart surgery. It may help protect the heart (and possibly kidneys) in people considered higher risk for complications.
San Francisco, CaliforniaAges 18 years+ - NCT05084196RecruitingPhase 3
Melatonin to help prevent kidney damage from vancomycin
This Phase 3 study tests whether melatonin can help protect the kidneys in people who are starting or continuing vancomycin, an antibiotic that can sometimes affect kidney function. If you qualify, you would take melatonin as an added prevention step while you’re on vancomycin.
New Brunswick, New JerseyAges 18–75 - NCT05149196Recruiting
Goal-directed fluid and blood pressure plan after kidney surgery
This trial tests a carefully tailored plan for managing blood pressure and fluid during and after kidney removal surgery, to help reduce kidney injury after surgery. It may be especially helpful if you’re having one kidney removed for cancer and your baseline heart/kidney risk is not too high.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05247502Recruiting
Study of kidney outcomes after ICU kidney injury
This study follows adults who stay in the ICU for more than 24 hours to see how an episode of acute kidney failure affects kidney health over the long term. Your participation helps researchers understand which ICU patients may need closer kidney monitoring later.
Clermont-FerrandAges 18 years+ - NCT05283512Recruiting
IV versus drink fluids to protect kidneys after CT scan
This study compares giving fluids through a vein versus drinking fluids to lower the risk of sudden kidney injury after a CT scan with contrast dye. It focuses on adults with very poor kidney function who are scheduled for an elective CT scan.
Odense C, FynAges 18 years+ - NCT05318196Recruiting
Predict kidney disease risk and progression from patient data
This trial looks at ways to predict how kidney disease may develop, change, or cause complications using information from patients. It may help doctors identify people at higher risk and tailor care earlier.
ToulouseAges 18–99 - NCT05659589Recruiting
Using a kidney toxin level to predict heart effects in AKI
This study looks at whether measuring indoxyl sulfate, a substance that can build up when kidneys are injured, can help predict how blood vessels and the heart are affected during acute kidney injury (AKI). It may help doctors understand who is at higher risk of heart-related problems while AKI is happening.
AmiensAges 18 years+ - NCT05694624Recruiting
Study of sepsis-related kidney injury monitoring
This trial looks at acute kidney injury that can happen during sepsis (a serious body-wide infection or suspected infection). It may help improve how doctors detect and manage kidney problems early, especially in intensive care or around major surgery.
Tromsø, TromsAges 18–100 - NCT05728216Recruiting
Using a special eye-scan to study kidney biopsy samples
This study tests whether a noninvasive “eye-scan” during a kidney biopsy can help doctors tell the difference between acute kidney injury and chronic kidney disease. If it works, it may improve how kidney problems are diagnosed in routine practice.
Chalon-sur-Saône, Saône-et-LoireAges 18 years+ - NCT05758077Recruiting
SeLective blood-filter trial for acute kidney injury in ICU
This trial tests a special device that filters parts of the blood to calm inflammation in people with severe acute kidney injury in the ICU. It may help improve recovery and reduce complications by “deactivating” certain immune cells.
Birmingham, AlabamaAges 18 years+ - NCT05806645Recruiting
Digital tools to guide recovery after a kidney injury
This study uses personalized risk information and digital tools to help people plan safe transitions after a recent hospital kidney injury. The goal is to better guide next steps and reduce the chance of future kidney problems.
Calgary, AlbertaAges 18 years+ - NCT05817539Recruiting
Early circulation-focused care during kidney dialysis in ICU
This trial looks at whether starting dialysis-related care early, aimed at improving blood flow to tissues, can help people in the ICU who have sudden kidney failure. It may help reduce problems related to poor tissue circulation, but it is very specific about ICU illness and current treatments.
AjaccioAges 18 years+ - NCT05879432RecruitingPhase 2
Peptide treatment to prevent or lessen kidney injury after heart surgery
This Phase 2 trial tests an LSALT peptide given around the time of “on-pump” heart surgery to help prevent or reduce acute kidney injury (a sudden drop in kidney function). It may help people who are at higher risk for kidney injury during or after surgery.
Calgary, AlbertaAges 18 years+ - NCT05909150RecruitingPhase 2
Hypertonic saline to protect kidneys after a heart transplant
This trial tests whether a hypertonic salt fluid (a higher-salt saline solution) can help prevent sudden kidney injury after heart transplant surgery. If you’re recently hospitalized for a heart transplant, you may be eligible if specific kidney support needs and critical breathing/circulation devices aren’t already required.
São PauloAges 18 years+ - NCT06026592Recruiting
Detecting kidney DNA in transplant patients' blood
This study looks for small pieces of kidney DNA in the blood of kidney transplant patients. It aims to improve monitoring of transplant health.
Paris, Île-de-France RegionAges 18 years+ - NCT06153147Recruiting
Kidney & blood pressure in childhood cancer survivors
This study looks at kidney health and blood pressure in childhood cancer survivors. If you finished high-risk cancer therapy about 3 years ago, researchers want to see how your kidneys and blood pressure are doing now.
Toronto, OntarioAges Up to 19 years - NCT06238310Recruiting
Comparing two markers to measure kidney function in intensive care
This trial compares two different substances, mannitol and iohexol, to see which one better measures how well your kidneys are filtering waste. It is for patients in intensive care with sudden or ongoing kidney problems, as well as stable chronic kidney disease patients seen in outpatient clinics.
GothenburgAges 18 years+ - NCT06291714Recruiting
Non-invasive blood pressure prediction during major surgery
This trial tests a new, non-invasive way to predict drops in blood pressure during major hip, knee, pelvis, or spine surgery. The goal is to help doctors prevent low blood pressure, which can lead to complications.
GiessenAges 45 years+ - NCT06337838RecruitingPhase 3
Preventing blood loss during surgery in kidney patients
This trial tests two medications, tranexamic acid and desmopressin, to see if they can reduce bleeding during surgery in people with severe kidney disease or on dialysis. The results may help make surgery safer for you.
London, OntarioAges 18 years+ - NCT06341062Recruiting
Ultrasound test for kidney injury in the ICU
This study tests whether a special ultrasound with a contrast dye can help doctors better assess acute kidney injury (a sudden drop in kidney function) in patients in the intensive care unit. If you or your loved one has been diagnosed with acute kidney injury within 24 hours of ICU admission, this imaging test may help guide care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06349577Recruiting
Bypass machine settings to protect kidneys during heart surgery
This study tests whether a special way of running the heart-lung bypass machine during planned heart surgery can help protect your kidneys and reduce the risk of kidney injury after the operation.
Aurora, ColoradoAges 18–85 - NCT06372444Recruiting
Kidney injury in severe infections study
This study looks at how severe infections like sepsis can hurt the kidneys. By using special scans (PET-CT), researchers hope to better understand why this happens, which could lead to better treatments.
UppsalaAges 30 years+
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Common questions
- Are there clinical trials for acute kidney injury?
- Yes. Clin2 currently lists 199 recruiting acute kidney injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute kidney injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute kidney injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.