Clinical trials
Adjuvant clinical trials
Below are recruiting adjuvant clinical trials, each written for real people, not researchers. We’re tracking 583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07679399RecruitingPhase 2
New combo therapy vs capecitabine for biliary tract cancer after surgery
This trial tests if a combination of immunotherapy (durvalumab), chemotherapy (GEMOX or GC), and a targeted therapy (lenvatinib) works better than standard capecitabine chemotherapy to prevent cancer from coming back after surgery for bile duct or gallbladder cancer.
BeijingAges 18–75 - NCT07675616Recruiting
Comparing two drugs for numbing the eye before tear-duct surgery
This trial tests whether adding dexmedetomidine or magnesium sulfate to lidocaine makes numbing the eye more effective for tear-duct surgery. The goal is to find which combination provides better pain control during surgery.
CairoAges 18 years+ - NCT05063136RecruitingPhase 3
Metronomic capecitabine with hormone therapy after breast cancer
This trial studies whether a low-dose “metronomic” chemotherapy medicine (capecitabine) added to standard hormone therapy can reduce breast cancer coming back. It is for people with hormone-receptor–positive, HER2-negative breast cancer after surgery and chemo.
Zhengzhou, HenanAges 18–70 - NCT05424692Recruiting
Test tumor drug sensitivity to guide after-surgery colon cancer care
This study looks at whether testing a small tumor sample can identify which medicines are more likely to work for colorectal cancer after surgery. The results are used to help choose the best “after-surgery” treatment plan, when you have not had chemotherapy before surgery.
Beijing, Beijing MunicipalityAges 18–75 - NCT06598761Recruiting
Immunotherapy plus radiation after surgery for advanced UTUC
This trial is testing whether adding immunotherapy and radiation after surgery can improve outcomes for people with advanced upper tract urothelial cancer (UTUC) who cannot have chemotherapy. It compares the combination to surgery alone.
BeijingAges 18–80 - NCT07670026RecruitingPhase 2
Stronger treatment after surgery for high-risk glioblastoma
This trial tests a more intense chemotherapy plan for people with glioblastoma who had only partial removal of their tumor or whose tumor grew back quickly. The goal is to see if this approach can improve outcomes.
Hangzhou, ZhejiangAges 18 years+ - NCT06341764RecruitingPhase 2
Chemo-immunotherapy before surgery for bile duct cancer
This trial tests a combination of chemotherapy and immunotherapy before surgery for locally advanced bile duct cancer. The goal is to see if this approach can shrink the tumor enough to improve surgical outcomes.
Naples, ItaliaAges 18 years+ - NCT05961059RecruitingPhase 1
Shigella vaccine safety study for healthy adults
This Phase 1 study tests a Shigella (gut infection) vaccine and additives to see how safe they are in healthy adults. If you qualify, you may help researchers understand whether the vaccine triggers any unwanted immune or stomach side effects.
LeidenAges 18–50 - NCT05965479RecruitingPhase 2
Blood test to guide extra stomach or esophagus cancer treatment
This trial checks whether a blood test after surgery (ctDNA) can help decide if you should receive additional “adjuvant” treatment for stomach, gastroesophageal junction, or lower esophagus cancer that has HER2-positive tumors. It may help reduce the chance of cancer coming back by tailoring therapy to your risk based on the ctDNA result.
Guildford, SurreyAges 18 years+ - NCT07643623RecruitingPhase 2/Phase 3
Immunotherapy for operable stomach cancer before and after surgery
This trial tests a combination of immunotherapy drugs (sintilimab, chemotherapy, and sometimes ipilimumab) given before surgery to shrink stomach or esophageal junction tumors, then continued after surgery. The goal is to improve survival in patients with resectable (removable) gastric or gastroesophageal junction cancer.
Guangzhou, GuangdongAges 18 years+ - NCT07643012Recruiting
Daily MRI-Guided Radiation for Endometrial Cancer
This trial tests whether using MRI scans daily during pelvic radiation therapy improves treatment precision and outcomes for endometrial cancer patients who need radiation after surgery. The goal is to better target cancer while reducing side effects.
New Brunswick, New JerseyAges 18–90 - NCT07640048Recruiting
Adjuvant therapy after surgery for high-risk bile duct cancer
This study tests additional treatment given after surgery to remove high-risk intrahepatic cholangiocarcinoma (a type of bile duct cancer). The goal is to reduce the chance the cancer comes back and improve survival in patients whose tumors had concerning features.
BeijingAges 18 years+ - NCT07640516Recruiting
Pain Relief Comparison for Amputation Surgery in High-Risk Patients
This study compares two medications (dexmedetomidine and fentanyl) mixed with a numbing agent to see which works better for blocking pain during above-knee amputation surgery in patients with serious heart or lung disease. Both drugs are already used in anesthesia, and this trial tests which combination is safest and most effective for you.
CairoAges 18 years+ - NCT07633197Enrolling by invitationPhase 1
Testing a new shingles vaccine for adults over 40
This study tests a new vaccine to protect against shingles (herpes zoster), a painful skin infection that can affect people as they age. You would receive the vaccine and be monitored to see if it's safe and how your body responds.
Zhengzhou, HenanAges 40 years+ - NCT07632118RecruitingPhase 3
Radiation and chemotherapy after pancreatic cancer surgery
This trial tests whether combining radiation therapy with chemotherapy (called the GX regimen) after pancreatic cancer surgery helps prevent cancer from returning in patients with high-risk features. The study aims to see if this combination treatment improves outcomes compared to standard care.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06693024Recruiting
Neratinib after standard therapy for HER2-positive early breast cancer
This trial is testing whether adding neratinib after standard treatment helps prevent HER2-positive early breast cancer from coming back. It is open only to patients treated at Peking University People's Hospital.
Beijing, Beijing MunicipalityAges Any age - NCT06693037Recruiting
Choosing next treatment after incomplete response in HER2+ breast cancer
This trial looks at the best next treatment for women with HER2-positive breast cancer who still have leftover cancer after surgery and standard pre-surgery treatment. It helps doctors choose the right therapy for you.
Beijing, Beijing MunicipalityAges Any age - NCT07626346Recruiting
Pain relief medication added to shoulder surgery nerve block
This trial tests whether adding a medication called dexmedetomidine to a numbing injection around shoulder nerves can improve pain control after laparoscopic shoulder surgery. The goal is to see if this combination works better than the numbing medication alone.
CairoAges 18–65 - NCT06587789Recruiting
Ribociclib plus hormone therapy for high-risk breast cancer
This trial tests adding ribociclib (a targeted pill) to standard hormone therapy for people with early but high-risk HR-positive, HER2-negative breast cancer, after surgery.
Hangzhou, ZhejiangAges 18–80 - NCT07618624Enrolling by invitationPhase 2
Drug combination before surgery for recurrent head and neck cancer
This trial tests three drugs (finotonlimab, cetuximab, and docetaxel) given before surgery to remove recurrent head and neck cancer in patients whose cancer stopped responding to previous immunotherapy. The goal is to shrink the tumor and improve surgical outcomes.
Foshan, GuangdongAges 18–75 - NCT07613151Recruiting
Lobular breast cancer with low hormone receptors
This study looks at a rare type of breast cancer called invasive lobular carcinoma that has low or no hormone receptors. The goal is to learn more about how this cancer behaves, which may help improve future treatments.
PadovaAges 18 years+ - NCT07618078Recruiting
Personalized Cancer Risk Assessment for Nasopharyngeal Cancer
This study helps doctors predict which patients with nasopharyngeal cancer (a cancer of the upper throat) will benefit most from additional chemotherapy after radiation treatment. It uses a special blood test and imaging to create a personalized risk score for each patient.
Beijing, Beijing MunicipalityAges 18–75 - NCT05891561RecruitingPhase 2
Short antibody treatment after surgery for early HER2+ breast cancer
This Phase 2 study tests a shorter schedule of trastuzumab and pertuzumab combined with chemotherapy (taxanes) to reduce breast cancer coming back after surgery. It mainly helps people with early-stage, HER2-positive breast cancer that has not spread, by testing whether a shorter plan still works well and is tolerable.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06710665Recruiting
Predicting adjuvant therapy success after esophageal cancer surgery
This trial looks at how well the tumor responded to chemotherapy or radiation before surgery, to see if that can help doctors decide next steps like additional treatment. It may help people with esophageal squamous cell cancer who had the tumor removed completely after initial therapy.
Fuzhou, FujianAges 18 years+
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Common questions
- Are there clinical trials for adjuvant?
- Yes. Clin2 currently lists 583 recruiting adjuvant studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adjuvant trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adjuvant trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.