Clinical trials
Advanced or Metastatic Breast Cancer clinical trials
Below are recruiting advanced or metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 6,141 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07575191RecruitingPhase 1/Phase 2
Novel Catheter for Direct Gemcitabine Delivery in Pancreatic Cancer
This trial tests a new catheter system that delivers gemcitabine (a chemotherapy drug) directly into pancreatic tumors. The goal is to see if this approach is safe and works better than standard intravenous chemotherapy for locally advanced pancreatic cancer that cannot be surgically removed.
SolnaAges 18 years+ - NCT07589569RecruitingPhase 2
HRS-7058 for Advanced Pancreatic Cancer Treatment
This study tests a new drug called HRS-7058 in patients with pancreatic cancer that has spread or cannot be removed by surgery. You may qualify if your cancer has already been treated with at least one prior therapy and you have measurable disease on imaging.
Nanjing, JiangsuAges 18–75 - NCT07596693RecruitingPhase 1
KXV01 injection for advanced solid tumors
This early-stage trial tests KXV01, a personalized cancer treatment made from your own immune cells, for advanced solid tumors that have not responded to standard treatment. The goal is to see if it can help control your cancer and learn about its safety.
ShanghaiAges 18–70 - NCT07601243RecruitingPhase 1
GS-2426 for advanced solid tumors with MTAP deficiency
This study tests a new drug called GS-2426 for people with advanced solid tumors that have a specific genetic change called MTAP deficiency. It may be an option if other treatments have stopped working or are not available.
East Brunswick, New JerseyAges 18 years+ - NCT07616297Recruiting
Higher Radiation Dose to Avoid Surgery in Rectal Cancer
This study tests whether giving a higher dose of radiation to rectal cancer tumors can help patients avoid surgery altogether. The goal is to shrink the tumor enough that surgery is no longer needed, preserving normal bowel function.
Rotterdam, South HollandAges 18 years+ - NCT07623902Recruiting
Testing a Tongue Scan to Detect Colorectal Polyps
This study tests whether a new tongue-scanning tool called Gixam can help find advanced colorectal polyps in people with negative stool tests. If it works, it might offer a simpler screening option alongside colonoscopy.
Orlando, FloridaAges 45–84 - NCT07637474Recruiting
Immune System and Lung Cancer Response to Immunotherapy
This study looks at how your immune system works in non-small cell lung cancer and whether it predicts how well you'll respond to a type of immunotherapy called anti-PD-1/PD-L1 drugs. Researchers will study your tumor tissue to understand why some patients benefit more than others.
Rome, RomeAges 18 years+ - NCT07638137Recruiting
Advanced Heart Catheter Testing for Stent Patients With Chest Pain
This study tests a detailed diagnostic procedure during heart catheterization for patients who previously had stents placed and now have chest pain or signs of heart stress. The goal is to better understand blood flow in treated arteries to guide treatment decisions.
Leganés, MadridAges 18 years+ - NCT07644039RecruitingPhase 1/Phase 2
PM54 plus immunotherapy for advanced cancer
This study tests a new drug called PM54 combined with pembrolizumab (an immunotherapy) in people with advanced cancers that have gotten worse despite prior treatment. The goal is to see if this combination can slow or stop cancer growth.
New York, New YorkAges 18 years+ - NCT07644286RecruitingPhase 2
Pirfenidone and immunotherapy with optional radiation for advanced colorectal cancer
This study tests a combination of three treatments—pirfenidone (an anti-scarring drug), a PD-1 inhibitor (an immunotherapy that helps your immune system fight cancer), and sometimes radiation—for colorectal cancer that has stopped responding to standard treatments. The goal is to see if this combination can slow or shrink your cancer.
Wuhan, HubeiAges 18–75 - NCT07645690RecruitingEarly Phase 1
CD70 CAR-T Cell Therapy for Advanced Kidney Cancer
This early-stage trial tests a new type of cell therapy called CD70 CAR-T for advanced kidney cancer (clear cell renal cell carcinoma) that has spread or cannot be surgically removed. The therapy uses cells from your own immune system that are genetically modified to recognize and attack cancer cells.
BeijingAges 18–75 - NCT07648472RecruitingPhase 1
Safety and efficacy of OVV-01 injection for advanced solid tumors
This study tests a new cancer treatment called OVV-01 that is injected directly into tumors or given through the vein. It's for patients with advanced solid cancers (like melanoma, lung, breast, or colon cancer) who have already tried at least two standard treatments without success.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07669220RecruitingPhase 2
Short radiation, immunotherapy, and chemo for advanced rectal cancer
This trial compares a new treatment approach—short-course radiation followed by an immunotherapy drug (PD-1 inhibitor) and chemotherapy (FOLFOX)—to the standard long-course chemoradiation for people with a specific type of advanced rectal cancer that is pMMR/MSS. The goal is to see if the shorter treatment works as well or better.
GuangzhouAges 18–75 - NCT07654036Enrolling by invitation
AI tool for lung cancer surgery decisions
This trial is testing a new AI tool that helps doctors make complex decisions about lung cancer surgery. Doctors will use the tool to review real patient cases and see if it helps them choose the best treatment.
Beijing, Beijing MunicipalityAges 18–65 - NCT07517692Enrolling by invitation
Improving shared decision-making for lung cancer screening
This study tests a new way to help patients and doctors discuss lung cancer screening together using text messages and shared decision-making tools. It may help you understand screening options better and make choices that fit your values.
Worcester, MassachusettsAges 50–77 - NCT07501624Enrolling by invitation
Pharmacist-led tobacco treatment for HIV patients
This study works with pharmacists at six Ryan White HIV clinics to help people with HIV quit smoking or using tobacco. If you have HIV, are 21 or older, and have already met with a pharmacist about tobacco, you may be able to join.
Charleston, South CarolinaAges 21 years+ - NCT07488572Enrolling by invitationPhase 2
AK112 for advanced clear cell kidney cancer
This study tests a new drug called AK112 (Yiwoxidan Anti) in people with advanced clear cell kidney cancer who cannot take TKI medications. The goal is to see if it is safe and effective.
Guangzhou, GuangdongAges 18–75 - NCT07405346Enrolling by invitation
Organoid-guided treatment for advanced leiomyosarcoma
This trial uses your tumor's lab-grown organoids to find the most effective personalized treatment for advanced leiomyosarcoma. It aims to match you with a drug that targets your specific cancer.
Wuhan, HubeiAges 18–75 - NCT07301983Enrolling by invitation
Testing a faster way to check lymph nodes in lung cancer surgery
This trial compares a new, quick test called OSNA to the standard method for checking lymph nodes in people with early-stage lung cancer who are having robotic surgery. The goal is to see if the new test works as well or better.
Pisa, PisaAges 18 years+ - NCT07284368Enrolling by invitation
Advance Choice Document study for mental health care
This study looks at how Advance Choice Documents (ACDs) can help people who have been detained under the Mental Health Act. It aims to understand how these documents are made and used, so that future care can better respect your wishes.
LondonAges 16 years+ - NCT07218562Enrolling by invitationPhase 2
Peer training to reduce burnout in harm reduction work
This trial tests whether a training program called PATH can help reduce burnout among peer support specialists and administrators who provide harm reduction services, like syringe or outreach programs.
Chicago, IllinoisAges 18 years+ - NCT07088809Enrolling by invitation
Nanoparticles with Platelet-Rich Fibrin for Gum Recession
This trial tests a new material to treat gum recession—tiny particles mixed with your own blood components (platelet-rich fibrin) placed as a membrane. The goal is to see if it helps cover exposed roots and improve gum health.
Tanta, Gharbia GovernorateAges 20–45 - NCT07053904Enrolling by invitationPhase 1
Study of two experimental cancer drugs for advanced solid tumors
This trial tests two new drugs, P1101 and P1801, in people with advanced solid tumors that have not responded to standard treatments. The goal is to see if the combination is safe and effective.
New Taipei CityAges 18 years+ - NCT07047937Enrolling by invitation
Machine learning to predict early gastric cancer
This study uses machine learning to find patterns in patient data that might help predict early-stage stomach cancer. It could help doctors catch the disease sooner.
Wenzhou, ZhejiangAges Any age
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Common questions
- Are there clinical trials for advanced or metastatic breast cancer?
- Yes. Clin2 currently lists 6,141 recruiting advanced or metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.