Clinical trials
Advanced or Metastatic Non-small Cell Lung Cancer clinical trials
Below are recruiting advanced or metastatic non-small cell lung cancer clinical trials, each written for real people, not researchers. We’re tracking 5,669 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06928701Recruiting
Diet and exercise for early breast cancer before surgery
This trial tests whether a personalized nutrition and exercise program can improve treatment response by changing how your body and immune system react to breast cancer before surgery. It is for women newly diagnosed with early-stage breast cancer who will receive neoadjuvant therapy (treatment before surgery).
Novara, NovaraAges 18 years+ - NCT06928818Recruiting
T-DM1 after T-DXd for advanced HER2-positive breast cancer
This trial looks at whether a different targeted therapy, T-DM1, can work for women with advanced HER2-positive breast cancer after they have already tried another targeted therapy called T-DXd (Enhertu). If you have progressed while on T-DXd and have not had more than three previous treatments for advanced cancer, you may be able to join.
SeoulAges 19 years+ - NCT06936735RecruitingPhase 1
HS-20108 for advanced solid tumors (phase 1)
This phase 1 study tests an investigational drug called HS-20108 in people with advanced solid tumors. It aims to find a safe dose and see how well the drug works against cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06940050Recruiting
Gum graft study for lower jaw recessions
This study compares two gum grafting methods (one using a special collagen material plus soft tissue, the other using soft tissue alone) to treat multiple gum recessions on the lower jaw. It may help find a better way to cover exposed roots and improve gum health.
Ghent, Oost-VlaanderenAges 18 years+ - NCT06958432RecruitingPhase 2/Phase 3
Short-course radiation plus chemo and immunotherapy for rectal cancer
This trial tests a treatment plan that uses a short course of radiation to the lymph nodes-sparing area, followed by chemotherapy and an immunotherapy drug (PD-1 inhibitor) for people with a specific type of mid or low rectal cancer (pMMR/MSS). The goal is to see if this approach can shrink the tumor and improve outcomes without needing extensive surgery.
Guangzhou, GuangdongAges 18–75 - NCT06959615RecruitingPhase 1/Phase 2
Study of JAB-23E73 for KRAS-Altered Advanced Tumors
This trial tests an experimental pill (JAB-23E73) for people with advanced solid tumors that have a specific KRAS gene change. It aims to see if the drug can shrink or slow the growth of these cancers.
Hefei, AnhuiAges Any age - NCT06959706RecruitingPhase 1
Study of TGW101 for advanced solid tumors
This trial tests a new drug called TGW101 for people with certain advanced solid tumors that have not responded to standard treatments. The goal is to see if it is safe and may help shrink tumors.
Scottsdale, ArizonaAges 18 years+ - NCT06966232RecruitingPhase 3
Using entecavir to prevent hepatitis B flare-up in gastrointestinal cancer patients
This trial tests whether giving the antiviral drug entecavir before or at the first sign of hepatitis B reactivation can prevent liver problems in gastrointestinal cancer patients who are inactive hepatitis B carriers and are starting chemotherapy or immunotherapy.
Guangzhou, GuangdongAges 18–75 - NCT06973564RecruitingPhase 1/Phase 2
JAB-23E73 for Advanced Solid Tumors with KRAS Changes
This trial tests a new drug called JAB-23E73 for people with advanced solid tumors that have a specific change in the KRAS gene. It may be an option if previous treatments have stopped working or are not suitable.
Rochester, MinnesotaAges 18 years+ - NCT06982066Recruiting
Helping Young Cancer Patients Talk with Their Care Team
This study works with teens and young adults (ages 15–25) who have cancer and are currently in treatment. It tests a way to help you talk better with your doctors and nurses about your care, so they can understand your needs and preferences more clearly.
Hartford, ConnecticutAges 15–25 - NCT07010198Recruiting
Comparing liver cancer screening methods for people with Hepatitis B
This study compares different ways to screen for liver cancer in people with chronic Hepatitis B. It is for adults living in Zhongshan City, China, who are 35 or older and have tested positive for Hepatitis B surface antigen (HBsAg). The goal is to find the best method to catch liver cancer early.
Zhongshan, GuangdongAges 35 years+ - NCT07025213Recruiting
Exercise and diet study for endometrial cancer before surgery
This study tests whether combining exercise with a special diet can improve how your body processes energy (metabolism) before you have surgery to remove the cancer. It is for people with early-stage endometrial cancer who haven't yet started treatment.
México, TlalpanAges 18–65 - NCT07033156Recruiting
Colorectal cancer detection using gene methylation test
This study is testing a new way to detect colorectal cancer early by looking for specific changes (gene methylation) in stool and blood samples. If you are 40 or older and have a colonoscopy scheduled, this non-invasive approach might help find cancer sooner.
Hangzhou, ZhejiangAges 40 years+ - NCT07036133RecruitingPhase 1
Study of Pralatrexate in patients with advanced cancer and liver problems
This trial tests a drug called pralatrexate in people with advanced solid tumors or blood cancers, including those with different levels of liver function. The goal is to understand how the drug works in the body and how safe it is for patients with various degrees of liver impairment.
Cerritos, CaliforniaAges 18 years+ - NCT07038629RecruitingPhase 2
Chemo, radiation, and immunotherapy for older adults with esophageal cancer
This trial tests combining chemoradiation with the immunotherapy drug iparomlimab for adults aged 70 and older with advanced esophageal cancer. The goal is to see if adding immunotherapy after standard chemoradiation improves outcomes.
Tianjin, Tianjin MunicipalityAges 70–90 - NCT07040657Recruiting
Comparing injection techniques for cervical lymph node mapping in endometrial cancer
This trial tests two different injection methods in the cervix to help map lymph nodes for endometrial cancer. The goal is to find which technique works better for staging, using a dye that helps surgeons see the lymph nodes during surgery.
AnkaraAges 18–75 - NCT07045311RecruitingPhase 2
JS207 combination therapy for triple-negative breast cancer
This trial tests a new combination treatment for people with advanced triple-negative breast cancer who have not yet received treatment for their advanced disease. It aims to see if the combination can help shrink or control the cancer.
Hefei, AnhuiAges 18–75 - NCT07046468Recruiting
Smart pill to check gut health in colon inflammation and cancer
This trial tests a smart pill that measures gut health in people with colon inflammation (ulcerative colitis) or colon cancer. It aims to see if the pill can help doctors better understand how the gut is working during treatment or before surgery.
Nijmegen, GelderlandAges 18 years+ - NCT07053488RecruitingPhase 1/Phase 2
Gene-edited liver transplant to lower rejection risk
This trial tests a liver transplant using a donor organ that has been gene-edited to reduce the risk of rejection. It may help people who need a liver transplant and are not a perfect tissue match with their donor.
Beijing, ChangpingAges 16–85 - NCT07054879Recruiting
Using a blood test to guide treatment after pancreatic cancer surgery
This trial is for people who had surgery for pancreatic cancer and are now deciding on maintenance therapy. A special blood test (ctDNA) may help doctors choose the best follow-up treatment to prevent the cancer from coming back.
Nanjing, JiangsuAges 18 years+ - NCT07065630RecruitingPhase 2
New immunotherapy for HPV-negative head and neck cancer
This trial tests a new immunotherapy drug called volrustomig for people with advanced head and neck cancer that is not caused by HPV. The goal is to see if giving this treatment based on how the cancer responds can help shrink tumors or stop them from growing.
Chicago, IllinoisAges 18 years+ - NCT07066098RecruitingPhase 3
New drug IBI343 for advanced pancreatic cancer with CLDN18.2 protein
This study tests a new drug called IBI343 compared to a placebo (inactive substance) for people with advanced pancreatic cancer that has a specific protein (CLDN18.2) and has not responded to earlier treatments. The goal is to see if IBI343 can help slow the cancer's growth.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07067385RecruitingPhase 1
Personalized mRNA vaccine for advanced GI cancers
This trial tests a personalized mRNA vaccine designed to teach your immune system to attack your specific tumor. It is for people with advanced gastrointestinal cancers who have exhausted other options.
Shanghai, SHAges 18 years+ - NCT07069842Recruiting
Gastric cancer immunotherapy prediction model
This study looks at markers in your tumor to predict how well immunotherapy might work for you. It aims to create a model that helps doctors choose the best treatment for advanced gastric cancer.
Changzhi, ShanxiAges 18–75
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Common questions
- Are there clinical trials for advanced or metastatic non-small cell lung cancer?
- Yes. Clin2 currently lists 5,669 recruiting advanced or metastatic non-small cell lung cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic non-small cell lung cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic non-small cell lung cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Locally Advanced or Metastatic Non-small Cell Lung Cancer
- Metastatic Non-squamous Non Small Cell Lung Cancer
- Advanced Non-squamous Non-small-cell Lung Cancer
- NSCLC (Advanced Non-small Cell Lung Cancer)
- Non Small Cell Lung Cancer Metastatic
- Non Small Cell Lung Cancer
- Non-squamous Non-small Cell Lung Cancer
- Locally Advanced Non-Small Cell Lung Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.