Clinical trials
Androgen Deprivation Therapy clinical trials
Below are recruiting androgen deprivation therapy clinical trials, each written for real people, not researchers. We’re tracking 72 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05753566RecruitingPhase 2
Rezvilutamide for prostate cancer PSA rise after prostate surgery
This Phase 2 study tests rezvilutamide in men whose prostate-specific antigen (PSA) starts rising again after the prostate has been removed. It aims to see whether this treatment can help prevent or slow cancer spread after surgery, especially in men without signs of spread on scans.
Nanjing, JiangsuAges 40 years+ - NCT05974774RecruitingPhase 3
Intermittent hormone therapy for metastatic prostate cancer with low PSA
This trial studies whether taking hormone therapy in breaks (instead of continuously) can work for people with metastatic prostate cancer whose PSA is very low after prior treatment with hormone-deprivation plus an AR pathway inhibitor. It may help reduce time on treatment while still keeping cancer controlled.
CopenhagenAges 18–100 - NCT06111313RecruitingPhase 2
Prostate cancer trial testing targeted radiation with hormone therapy
This trial tests a new radiation approach for prostate cancer that has not spread. It combines different types of radiation with or without hormone therapy to see if this approach works better with fewer side effects.
Miami, FloridaAges 35–85 - NCT06130995RecruitingPhase 1
Relugolix and enzalutamide for high-risk prostate cancer
This trial tests a combination of two oral drugs, relugolix and enzalutamide, in men with high-risk prostate cancer that hasn't spread to distant parts of the body. The goal is to see if this treatment can help control the cancer before or alongside local therapies like surgery or radiation.
Oklahoma City, OklahomaAges 18 years+ - NCT06171269Recruiting
MRI-guided radiation dose reduction for prostate cancer
This trial tests whether using MRI scans to guide radiation can allow lower doses to the healthy parts of the prostate, potentially reducing side effects. It is for men with intermediate- or high-risk prostate cancer that can be seen on MRI and has not spread.
Chicago, IllinoisAges 18 years+ - NCT06172283Recruiting
Intermittent fasting with hormone therapy for prostate cancer
This trial tests whether intermittent fasting (alternating between eating and not eating for certain periods) can help men with prostate cancer who are receiving hormone therapy (androgen deprivation therapy). It aims to see if fasting during treatment can reduce side effects or improve how well the therapy works.
Buffalo, New YorkAges 18 years+ - NCT06449664Recruiting
Exercise program for men on hormone therapy for prostate cancer
This study tests whether a supervised exercise program can help men with prostate cancer stay stronger and feel better during combined radiation and hormone therapy. You may be able to join if you are about to start these treatments and are otherwise healthy enough to exercise.
StockholmAges 50–80 - NCT06582446RecruitingPhase 2
AI-Personalized Radiation for High-Risk Prostate Cancer
This trial tests a new way to plan prostate cancer treatment using artificial intelligence and advanced imaging. It’s for people with high-risk prostate cancer that hasn’t spread to lymph nodes or other parts of the body, and who have not had prior radiation to the prostate.
LimassolAges 18 years+ - NCT06687421Recruiting
Precision medicine for high-risk prostate cancer
This study aims to use precision medicine (tailored treatment based on your specific cancer) for men at high risk of prostate cancer. It may help doctors choose the best treatment for you.
UmeåAges 18 years+ - NCT06908694RecruitingPhase 4
GLP-1 drugs for weight management in prostate cancer
This trial tests if a GLP-1 receptor agonist (a type of diabetes drug that helps with weight loss) can help men with prostate cancer who are on hormone therapy (ADT) and have a high body mass index (BMI). It aims to see if it improves their health and outcomes.
Hamilton, OntarioAges 18 years+ - NCT06972875RecruitingPhase 2
Testing a hot flash pill for men on prostate cancer therapy
This trial tests a non-hormonal pill called fezolinetant to reduce hot flashes in men with prostate cancer who are on hormone therapy. If you have daily, bothersome hot flashes, this study may help you find relief.
Burlington, VermontAges 18 years+ - NCT07025369RecruitingPhase 2
Hormone pill before PSMA scan for high-risk prostate cancer
This trial tests if giving a short-term hormone pill (relugolix) before a special PSMA PET/CT scan makes the scan clearer for men with high-risk prostate cancer. It may help doctors better see where the cancer is.
Scottsdale, ArizonaAges 18 years+ - NCT07032584Recruiting
Tele-rehab for rural men with metastatic prostate cancer
This trial tests a home-based exercise and support program delivered by phone or video for men with metastatic prostate cancer living in rural areas. The goal is to see if this approach improves quality of life and physical function compared to standard care.
Salt Lake City, UtahAges 21 years+ - NCT07163910RecruitingPhase 2
Homoharringtonine plus hormone therapy before prostate surgery
This trial tests whether adding a drug called homoharringtonine (a type of chemotherapy) to standard hormone therapy before prostate surgery can improve outcomes for men with certain stages of prostate cancer. It's for men who haven't had any previous treatment and plan to have their prostate removed.
Nanjing, JiangsuAges 18–85 - NCT07483658Recruiting
Salvage pelvic radiotherapy: 20 vs 25 sessions for recurring prostate cancer
This trial compares two schedules of pelvic radiotherapy for men whose prostate cancer has returned after surgery. Both schedules aim to control the cancer with fewer visits for one of them.
Gatineau, QuebecAges 18 years+ - NCT02102477Recruiting
Surgery or radiation for prostate cancer in the pelvis
This trial compares surgery versus radiation for men with locally advanced prostate cancer that has not spread to distant sites. It aims to see which treatment works better and is easier to manage for people like you.
AalborgAges 18–75 - NCT03129854Recruiting
ADT with or without freezing the prostate for spread cancer
This trial compares standard hormone therapy (ADT) alone versus ADT plus a procedure that freezes the prostate (cryoablation) in people whose prostate cancer has spread. It looks to see whether adding freezing improves outcomes while keeping treatment safe.
Guangzhou, GuangdongAges 18–90 - NCT07463092Recruiting
Creatine and exercise for muscle health in prostate cancer
This study tests whether taking creatine and doing weightlifting exercises can help men with prostate cancer who have been on hormone therapy for at least 6 months to improve muscle strength and size. It lasts 12 weeks and involves supervised workouts three times per week.
São Paulo, São PauloAges 40 years+ - NCT07535541Recruiting
Smartwatch Study of Hot Flashes in Prostate Cancer Patients
This study tests whether a smartwatch can accurately measure hot flashes (sudden heat and sweating) that occur in men undergoing hormone therapy for prostate cancer. You'll wear the smartwatch for about 4 weeks while the research team tracks your symptoms.
Charlottesville, VirginiaAges 18 years+ - NCT06872619Enrolling by invitation
Prostate Cancer Research Registry
This registry collects information from people with prostate cancer to help researchers better understand the disease and improve future treatments.
MünsterAges 45–100 - NCT03880422Recruiting
Exercise and nutrition for weight and frailty after prostate cancer treatment
This study tests whether a structured exercise and nutrition program can improve obesity-related frailty and overall function in people with advanced prostate cancer who are taking hormone therapy (ADT). It may help with strength, mobility, and healthier body weight during/after ADT.
Buffalo, New YorkAges 18 years+ - NCT04704505RecruitingPhase 2
Testosterone-like treatment plus radium for bone-spread prostate cancer
This trial studies whether adding a testosterone-related therapy (BAT) to radium-223 can better control prostate cancer that has spread mainly to the bones. It may help shrink tumors in the bone and slow PSA rises, which are a common marker of prostate cancer activity.
Baltimore, MarylandAges 18 years+ - NCT06636123RecruitingPhase 1
Testing GZ17-6.02 for advanced prostate cancer after hormone therapy
This trial tests a new drug combination (GZ17-6.02) for men with advanced prostate cancer that has stopped responding to standard hormone therapies. The goal is to see if the drug can help slow down the cancer.
Richmond, VirginiaAges 18 years+ - NCT05593497RecruitingPhase 2
Study of hormone therapy plus capivasertib before prostate surgery
This Phase 2 trial tests whether adding capivasertib to intensified hormone therapy (leuprolide plus abiraterone) given before prostate surgery can improve outcomes for men with high-risk localized prostate cancer that has a specific tumor marker (PTEN loss). You would also have extra blood tests, scans, and a tissue biopsy for tumor testing.
West Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for androgen deprivation therapy?
- Yes. Clin2 currently lists 72 recruiting androgen deprivation therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a androgen deprivation therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a androgen deprivation therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.