Clinical trials
Sleep Deprivation clinical trials
Below are recruiting sleep deprivation clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06180837Recruiting
Can longer sleep improve heart health in overweight adults?
This study tests if getting more sleep (7+ hours) can lower certain fats in the blood called ceramides, which are linked to heart disease risk. It's for overweight adults who currently sleep less than 6.5 hours a night.
Salt Lake City, UtahAges 18–45 - NCT03767426Recruiting
Study how sleep loss affects memory and emotions
This study looks at how losing sleep—and then getting recovery sleep—changes emotional memory and emotional reactions. It may help researchers understand why sleep affects mood and thinking, and what could improve these effects.
Boston, MassachusettsAges 18–35 - NCT05309473Recruiting
Sounds during restricted sleep after being sleep deprived
This study tests whether playing certain sounds during a period of limited sleep can affect how your body responds after you’ve been kept awake. It’s designed for healthy adults and checks safety and how well you can follow the study instructions.
Silver Spring, MarylandAges 18–39 - NCT06679543Recruiting
How partial sleep loss affects heart function during cycling
This study looks at how a night of poor sleep affects your heart's ability to pump blood while you ride a bike. It may help find out why sleep loss can be hard on the heart.
Guelph, OntarioAges 18–50 - NCT06928168Recruiting
Sleep extension to prevent sleep loss in active adults
This trial tests if sleeping more can help active people avoid the negative effects of not getting enough sleep. It might be a good fit if you exercise regularly and usually sleep 6 to 8 hours a night.
Saint-EtienneAges 18–50 - NCT07085754Recruiting
Sleep loss and brain health in people with different APOE genes
This study looks at how one night of no sleep affects thinking and brain function in healthy young adults who have different versions of the APOE gene. It aims to understand why some people might be more sensitive to sleep loss.
Guangzhou, GuangdongAges 18–40 - NCT06620601Recruiting
Digital technology for sleep and homelessness
This study explores how digital tools can help improve sleep for people living in shelters. It aims to test whether wearable devices or apps can support better sleep habits and health.
Toronto, OntarioAges 18 years+ - NCT06737055Recruiting
Sleep help for new and expectant parents
This study tests a sleep program for pregnant women and new moms. It uses specially trained helpers to teach better sleep habits, which may improve your rest and well-being.
Providence, Rhode IslandAges 18–99 - NCT05393830Recruiting
Study tests how sleep loss affects emotion control
This study looks at how losing sleep changes a person’s ability to manage emotions. You may need to do brain scans (fMRI), and you would be asked to avoid alcohol and recreational drugs during the study.
Boston, MassachusettsAges 18–40 - NCT07329283Recruiting
Nighttime nutrition and sleep health study
This study looks at how eating at night affects your sleep and body clock. You will spend two nights in a sleep lab to test the effects of a small meal before bed.
Salt Lake City, UtahAges 18–35 - NCT06684444Enrolling by invitationPhase 4
Sleep coaching study for firefighters with sleep troubles
This study tests if health coaching can help career firefighters sleep better. You'll have private coaching sessions by phone or computer.
Tucson, ArizonaAges 18 years+ - NCT07293494Recruiting
Spaceflight stress and brain changes study
This study looks at how the stress of spaceflight affects the brain and behavior. You will complete tasks and have MRI scans while staying in a controlled environment, including some sleep disruption and alcohol consumption.
Philadelphia, PennsylvaniaAges 21–60 - NCT06482814Recruiting
Sleep restriction and family history of high blood pressure
This study looks at how restricting sleep affects blood pressure in young adults. It is especially interested in people whose parents have high blood pressure, to understand if family history plays a role.
Rochester, MinnesotaAges 18–35 - NCT06336525Enrolling by invitation
Sleep health in rural Appalachia and Mississippi Delta
This study examines how sleep is linked to heart and metabolic health in people living in rural Appalachia and the Mississippi Delta. If you are already part of the RURAL Study, you may be able to join this sleep-focused part of the research.
Boston, MassachusettsAges 25–65 - NCT07438912Recruiting
Mind After Midnight: A study on late-night thinking and suicide risk
This study looks at how thinking changes late at night in people who have had suicidal thoughts in the past 6 months. The goal is to understand risk and find better ways to help.
Tucson, ArizonaAges 18–55 - NCT07084701Recruiting
Lymphatic drainage for memory in sleep-deprived college students
This study tests if a gentle, non-invasive neck and head massage technique, called lymphatic drainage, can help improve memory and thinking in college students who are not sleeping enough. It is a preliminary study to see if the idea works.
TianjinAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT06081998Recruiting
How lack of sleep affects itch and pain
This study looks at how not sleeping affects your sensitivity to itch and pain. Researchers want to understand the connection between sleep and these sensations, which could help treat conditions like chronic itching or pain.
AalborgAges 18–60 - NCT06683248Recruiting
Night shifts and menstrual cycle health study
This study looks at how working night shifts affects your health throughout your menstrual cycle. It aims to help understand the risks and support better health for shift workers.
Uppsala, Uppsala CountyAges 18–35 - NCT02945501Recruiting
Brain stimulation during sleep to improve slow-wave brain timing
This study tests a non-painful brain stimulation during the first part of sleep to see how it affects slow, deep-sleep brain rhythms. It is mainly for healthy young adults who can follow a strict sleep schedule.
Bethesda, MarylandAges 18–39 - NCT05775627Recruiting
Study how sleep affects metabolism in healthy adults
This trial studies how changes in sleep and the body’s daily rhythm may affect metabolism (how your body handles energy and sugar). It is for generally healthy, medication-free young adults who follow a controlled diet and sleep schedule.
Portland, OregonAges 18–40 - NCT06492109Recruiting
Blood study on sleep loss
This study looks at blood samples to understand how sleep loss affects the body. It may help find new ways to diagnose or treat sleep problems.
Hangzhou, ZhejiangAges 18–80 - NCT06399939Recruiting
Biphasic sleep in 9-month-old infants
This study looks at how infants sleep in two different patterns (biphasic sleep) and how that relates to their development. If your child is 9 months old and healthy, researchers will track their sleep and development over the next 6 months.
Amherst, MassachusettsAges 9 months–1.3 years - NCT06075914Recruiting
Ketones and sleep: can nutrition help?
This study tests if a special nutritional supplement (ketones) can help your body stay resilient when you don't get enough sleep. If you join, you'll follow a specific diet and have your sleep and health monitored for about 9 weeks.
Columbus, OhioAges 18–40
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Sleep Deprivation trials by city
Studies with a site in or near these metro areas.
Sleep Deprivation trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for sleep deprivation?
- Yes. Clin2 currently lists 32 recruiting sleep deprivation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sleep deprivation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sleep deprivation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.