Clinical trials
Anterior Cruciate Ligament Rupture clinical trials
Below are recruiting anterior cruciate ligament rupture clinical trials, each written for real people, not researchers. We’re tracking 67 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07129694Enrolling by invitation
Testing a new lab-grown ligament for ACL repair
This study tests a new, lab-grown ligament made from biological tissue for ACL reconstruction. It may offer a regenerative option for people with a recent ACL tear who need surgery.
Hirosaki, AomoriAges 18–44 - NCT06961292Enrolling by invitation
Knee ligament surgery study for ACL tears with extra rotation
This study compares two surgery techniques for ACL tears where the knee also twists too much inward. It aims to find which method leads to better long-term knee stability.
BeijingAges 18 years+ - NCT06892899Enrolling by invitation
Exercise study for knee health after ACL surgery
This study tests whether a specific exercise program can improve knee health in people who have had ACL surgery. It aims to understand how exercise affects the knee after injury and may help prevent arthritis.
Oslo, OsloAges 16–40 - NCT06755398Enrolling by invitation
Cognitive exercises after ACL knee surgery
This trial tests whether adding mentally challenging exercises to physical therapy helps improve balance, joint awareness, and reaction time after ACL reconstruction. It may be a good fit if you are at least 8 weeks post-surgery, have completed initial rehab, and meet specific recovery milestones.
AntalyaAges 20–40 - NCT06189573Enrolling by invitation
ACL repair: quadriceps vs patellar tendon graft
This trial compares two ways to rebuild a torn ACL using either a piece of your quadriceps tendon (with a small bone piece) or a piece of your patellar tendon (with bone). The goal is to find which graft works best for long-term stability and recovery.
Mexico City, Mexico CityAges 15–55 - NCT04650568Enrolling by invitation
Stem cell treatment after ACL ligament surgery
This trial studies whether adding mesenchymal stem cells during ACL (knee ligament) reconstruction helps the knee heal better. You might be eligible if your ACL injury is recent and you’re having a specific type of graft surgery.
Chicago, IllinoisAges 18–60 - NCT07765173Recruiting
Muscle function after ACL reconstruction in active people
This study looks at how well your thigh muscles work after ACL reconstruction surgery. It aims to understand muscle power recovery in active people, which could help improve rehabilitation programs.
Challes-les-EauxAges 18–65 - NCT04462458Recruiting
Study tracking outcomes after ACL reconstruction surgery
This is a study that follows adults who had an ACL tear treated with ACL reconstruction. It helps understand how the surgical device/material performs in real-world care.
InnsbruckAges 18 years+ - NCT06688344Recruiting
Shock wave therapy after ACL surgery
This trial tests if adding focused shock wave therapy to standard rehab can improve recovery after ACL reconstruction using a hamstring graft. It may help reduce pain and speed up healing.
IstanbulAges 18–45 - NCT06818201Recruiting
Brain stimulation for ACL surgery recovery
This study tests if a gentle, noninvasive brain stimulation called tDCS can improve how your brain controls leg muscles and speeds up recovery after ACL surgery.
Valencia, ValenciaAges 16–40 - NCT05754632Recruiting
Blood flow restriction exercises after ACL surgery in teens
This trial tests whether a special type of exercise that uses a cuff (blood flow restriction training, or BFRT) can help teens recover after ACL reconstruction. It’s designed to see if adding BFRT to standard rehab improves strength and return to sport.
Farmington, ConnecticutAges 12–18 - NCT05953051Recruiting
ACL surgery with a tunnel widened using enriched bone
This trial compares two techniques for ACL reconstruction—one uses an enriched, patient’s own bone during surgery and the other uses the standard approach. It may help researchers understand whether the enriched bone method improves knee healing and function.
ZurichAges 18–50 - NCT06206200Recruiting
Thinking and moving after ACL surgery
This study looks at how doing a thinking task at the same time as a walking or balance task affects recovery in people who have had ACL reconstruction surgery. It may help you understand what to expect during later stages of rehab.
Roeselare, West-VlaanderenAges 18–40 - NCT06529692Recruiting
Split-belt treadmill training after ACL reconstruction
This study tests whether walking on a special split-belt treadmill (where each belt moves at a different speed) can help improve how your knee moves and feels after ACL reconstruction. The goal is to see if this training leads to better long-term knee health.
Ann Arbor, MichiganAges 14–45 - NCT06571240Recruiting
Turkish Activity Score Tool for ACL Surgery Patients
This study checks if a new Turkish version of an activity score (Tegner) is valid and reliable for people having ACL surgery. If you are having your first ACL repair and speak Turkish, you may be able to take part.
AnkaraAges 18 years+ - NCT06571227Recruiting
Understanding knee scores after ACL surgery
This study aims to find what a 'normal' knee score (Lysholm score) means for people after ACL surgery. It will help doctors know if your recovery is on track.
AnkaraAges 18 years+ - NCT07306221Recruiting
Balance training after ACL surgery using visual guides
This study tests if a special video-based balance training program helps people recover knee function better after ACL reconstruction surgery. It is designed for patients who had surgery within the past year using their own hamstring tendon.
BeijingAges 18–45 - NCT02918734Recruiting
ACL surgery: compare two ways to secure the tendon graft
This study looks at two surgical methods to attach the tendon graft during ACL reconstruction, using either an Endobutton or metal interference screws. It may help patients by improving how securely the graft is fixed and how well recovery goes.
TrondheimAges 18–55 - NCT07404046Recruiting
Comparing tendon grafts for ACL surgery
This trial compares two types of grafts using the semitendinosus tendon for ACL reconstruction. It aims to see if adding a part of the tendon's muscle improves healing and stability after surgery.
ZagrebAges 18–50
Hear when a new Anterior Cruciate Ligament Rupture trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for anterior cruciate ligament rupture?
- Yes. Clin2 currently lists 67 recruiting anterior cruciate ligament rupture studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament rupture trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament rupture trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament
- Anterior Cruciate Ligament (ACL) Reconstruction
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.