Clinical trials
Anterior Cruciate Ligament Tear clinical trials
Below are recruiting anterior cruciate ligament tear clinical trials, each written for real people, not researchers. We’re tracking 45 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06875427RecruitingPhase 3
Nerve block vs no block for ACL surgery in kids
This trial tests whether a nerve block (a numbing shot) before ACL reconstruction helps young patients have less pain and better recovery compared to no block.
Hamilton, OntarioAges 10–18 - NCT06948591Recruiting
BioBrace® Support in ACL Reconstruction Surgery
This study looks at how well a special tissue support called BioBrace® works when used during ACL reconstruction surgery. It follows patients who have already had the surgery or are planning to have it, to see how their knee recovers over time.
New Haven, ConnecticutAges 14–70 - NCT06956339Recruiting
Bracing vs Surgery for First-Time ACL Tear
This trial compares a new bracing treatment (Cross Bracing Protocol) versus standard surgery for people who have torn their ACL for the first time. It aims to see which approach leads to better recovery and fewer complications.
Melbourne, VictoriaAges 16–40 - NCT06974526RecruitingPhase 2
Hormone implant for ACL surgery recovery
This trial tests a small implant that slowly releases the hormone oxandrolone to help you recover strength and function faster after ACL reconstruction surgery. It is for people who are already active and have no major health problems that could interfere with the medicine.
Fortaleza, CearáAges 18–60 - NCT06979804Recruiting
Comparing knee surgery outcomes with special fabric products
This study compares how well people do after anterior cruciate ligament (ACL) surgery, with or without also repairing the meniscus, using a special fabric product. It aims to see if the fabric helps improve recovery and outcomes for people with these common knee injuries.
Westmont, IllinoisAges 16–65 - NCT07366619Recruiting
MADI ACL study: a new MRI method for ligament repair
This trial tests a new MRI technique called Magic Angle Direction Imaging (MADI) to see if it can give better images of the knee before ligament repair surgery. It may help doctors plan your surgery more accurately.
LondonAges 18–65 - NCT02511158Recruiting
Knee ligament surgery study after ACL reconstruction
This study follows people who have a knee ligament tear and undergo surgery to rebuild the ligament. It may help doctors better understand recovery and outcomes after different surgical techniques.
ParisAges 7 years+ - NCT07423767Recruiting
Counseling before ACL surgery to reduce fear and improve recovery
This study tests whether a short counseling program before ACL surgery can help reduce fear of movement and improve recovery. If you are preparing for your first ACL reconstruction, this program may help you feel more confident and get back to activities sooner.
Beijing, None SelectedAges 18–45 - NCT07485530Recruiting
Testing ultrasound strain tracking for physical therapy
This trial tests whether a new ultrasound method (speckle tracking) can measure soft tissue movement and strain to help guide physical therapy. It is looking for three groups: male pitchers, people with a foot tendon problem needing surgery, and people who had ACL knee surgery.
TaipeiAges 18–65 - NCT07501013Recruiting
Shoulder and knee surgery outcomes study
This study looks at how well different types of shoulder and knee surgeries work for sports injuries. It aims to help improve future care by following patients' recovery after common procedures like fixing torn cartilage or repairing ligaments.
Hangzhou, ZhejiangAges 8–80 - NCT07636278Recruiting
Augmented Reality guidance for ACL knee surgery
This trial tests whether using augmented reality (special computer graphics overlaid on surgical video) during ACL reconstruction surgery helps surgeons perform the procedure more accurately. You would undergo standard knee surgery, but the surgeon would have real-time computer guidance to assist with precision.
Milan, MichiganAges 18 years+ - NCT06755398Enrolling by invitation
Cognitive exercises after ACL knee surgery
This trial tests whether adding mentally challenging exercises to physical therapy helps improve balance, joint awareness, and reaction time after ACL reconstruction. It may be a good fit if you are at least 8 weeks post-surgery, have completed initial rehab, and meet specific recovery milestones.
AntalyaAges 20–40 - NCT06668376Enrolling by invitation
Incrediwear recovery products after ACL repair surgery
This study is testing Incrediwear recovery products (like sleeves or wraps) to see if they help reduce pain and swelling and improve healing after ACL repair. If you're having ACL surgery and meet the health requirements, you may be able to join.
Denton, TexasAges 18–65 - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT03365908Enrolling by invitation
Pain Management After ACL Reconstruction Surgery
This study looks at ways to manage pain in adults who are getting surgery to repair a torn ACL (a knee ligament). It may help improve comfort and recovery after ACL reconstruction.
Sacramento, CaliforniaAges 18–45 - NCT06178497Recruiting
5-Year Check-In After ACL Repair
This study checks on people who had ACL (anterior cruciate ligament) repair surgery 5 years ago to see how well their knee is doing. It looks at a specific type of ACL tear (a 'proximal' tear) and helps doctors understand long-term results.
Lille, Choisir Une RégionAges 18 years+ - NCT06818201Recruiting
Brain stimulation for ACL surgery recovery
This study tests if a gentle, noninvasive brain stimulation called tDCS can improve how your brain controls leg muscles and speeds up recovery after ACL surgery.
Valencia, ValenciaAges 16–40 - NCT03968913RecruitingEarly Phase 1
Biologic shot to prevent knee arthritis after ACL injury
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
Los Angeles, CaliforniaAges 18–35 - NCT05342441Recruiting
Choosing the best ligament graft for ACL repair
This study looks at how different “grafts” (tissue used to rebuild the ACL) affect outcomes after first-time ACL reconstruction. It may help personalize graft choice for people who want to return to physical activity.
HvidovreAges 18–40 - NCT06442319Recruiting
PRP after ACL reconstruction
This trial tests if injecting platelet-rich plasma (a concentration of your own blood platelets) after ACL reconstruction helps with healing and reduces pain. It's for people who recently had ACL surgery and want to try an extra treatment to improve recovery.
TorunAges 18–45 - NCT07306221Recruiting
Balance training after ACL surgery using visual guides
This study tests if a special video-based balance training program helps people recover knee function better after ACL reconstruction surgery. It is designed for patients who had surgery within the past year using their own hamstring tendon.
BeijingAges 18–45
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Common questions
- Are there clinical trials for anterior cruciate ligament tear?
- Yes. Clin2 currently lists 45 recruiting anterior cruciate ligament tear studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament tear trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament tear trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament
- Anterior Cruciate Ligament (ACL) Reconstruction
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.