Clinical trials
Anterior Cruciate Ligament clinical trials
Below are recruiting anterior cruciate ligament clinical trials, each written for real people, not researchers. We’re tracking 152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04183803Recruiting
Robot help to set the right position for ACL surgery
This study tests whether using a robot to help place the tunnel during ACL (knee ligament) reconstruction is better or more accurate than the usual approach. You may benefit if you need ACL surgery and your care team has robot experience.
AmiensAges 10 years+ - NCT04295148Recruiting
Compare brace and rehab for ACL reconstruction
This study compares two ways of rehabilitating the knee after ACL rupture repair. It’s meant to see which approach helps people return to their prior sport more safely and effectively.
Stockholm, Stockholm CountyAges 16–40 - NCT04770233Recruiting
Comparing early surgery options for torn ACL
This study looks at the best way to treat a fresh ACL (an important knee ligament) tear by comparing an “early surgery” plan that starts within 12 weeks. It may help guide care and recovery for people who are able to do both the surgery and the follow-up rehabilitation.
Lørenskog, AkershusAges 16–50 - NCT04781920Recruiting
Follow-up after ACL ligament surgery
This study is checking how people are doing after anterior cruciate ligament (ACL) reconstruction (a surgery to repair a knee ligament). It may help researchers understand recovery and long-term outcomes after ACL surgery.
Saint-EtienneAges 18 years+ - NCT05174611RecruitingPhase 2
Vitamin D to strengthen the thigh after ACL surgery
This Phase 2 study tests whether taking vitamin D can improve thigh (quadriceps) muscle strength after ACL reconstruction. It targets people with low vitamin D levels that persist after surgery and weaker thigh strength on the injured side.
Hong KongAges 18–40 - NCT05207943Recruiting
Testing an at-home device for ACL knee injuries
This study tests whether the NXSignal device can help people recover from an anterior cruciate ligament (ACL) injury. You’d use the device while the study team monitors your progress using questionnaires.
Las Palmas de Gran Canaria, Las PalmasAges 16 years+ - NCT05323474Recruiting
Rehab program after ACL surgery to return to competitive sport
This study tests an “optimized” rehabilitation plan after ACL reconstruction to help people safely return to competitive sports. It’s for people who had an ACL surgery and still want to play sports that involve cutting, pivoting, or contact.
Challes-les-EauxAges 18–25 - NCT05501210Recruiting
Knee vibration therapy for ongoing front-of-knee pain after ACL surgery
This trial studies whether a vibrating device on the front of the knee can reduce persistent pain after ACL reconstruction. It may help people whose pain is focused in one knee and isn’t caused by arthritis or other knee problems.
Hong KongAges 18–60 - NCT05701579Recruiting
Testing treatment choices for early ACL cartilage changes before surgery
This trial looks at a treatment strategy for people with specific early changes in the ACL seen on MRI who are planning knee surgery. It may help by testing the best way to address those ACL-related cartilage/mucosa-like changes before or during surgical care.
Bełchatów, Łódź VoivodeshipAges Any age - NCT05747079Recruiting
Early versus delayed surgery after a new ACL tear
This study compares immediate surgery versus waiting a short time for people with a new ACL injury. It aims to see which timing leads to better recovery and knee function.
LeuvenAges 16 years+ - NCT05965310Recruiting
Virtual psychology support for ACL repair recovery
This study tests a virtual (online) psychological program to help people recover after ACL ligament surgery. It focuses on first-time ACL repairs and aims to improve how patients cope during recovery.
Detroit, MichiganAges 13 years+ - NCT06190223Recruiting
ACL repair using kneecap tendon with press-fit method
This study looks at a specific ACL reconstruction technique using a graft from your kneecap tendon that is fixed with a press-fit method. It aims to determine how well patients recover after at least one year.
AnkaraAges 18–55 - NCT06194682Recruiting
ACL reconstruction follow-up study
This study follows people who have had or will have ACL reconstruction surgery at this hospital. It helps doctors learn more about how patients recover after ACL surgery over the long term.
MilanAges 18–65 - NCT06311513RecruitingPhase 4
Concentrated bone marrow injection during repeat ACL surgery
This study tests whether adding a concentrated bone marrow injection during repeat ACL surgery helps healing and recovery better than surgery alone. If you have had a previous ACL reconstruction that failed, you may be eligible.
Atlanta, GeorgiaAges 18–55 - NCT06341192Recruiting
Comparing two ways to reconstruct the ACL
This trial compares two different techniques for ACL surgery (single bundle vs. double bundle) to see which one works better. If you're planning to have ACL surgery, you may be able to join.
Taoyuan, taoyuanAges 18 years+ - NCT06341868Recruiting
Electrical stimulation for ACL recovery in military cadets
This trial tests whether a special electrical stimulation device (KneeStim) can help military academy cadets recover faster after ACL reconstruction surgery. It aims to improve muscle strength and knee function using gentle electrical pulses during rehabilitation.
West Point, New YorkAges 17–27 - NCT06353503Recruiting
Bone marrow treatment for ACL tears
This study tests if bone marrow concentrate injected into the knee can help repair a torn anterior cruciate ligament (ACL), which is a common sports injury. It aims to improve healing and reduce the need for surgery.
BaghdadAges 20–55 - NCT06357091Recruiting
ACL repair with Shark Screw or standard screw
This trial compares two types of screws used to hold a new ACL in place: a Shark Screw and a standard biocomposite screw. It may help if you have a torn ACL that needs surgery.
Schwaz, TyrolAges 18 years+ - NCT06368544Recruiting
Early walking training after ACL knee surgery
This trial studies whether starting walking exercises earlier after ACL reconstruction can help protect the knee cartilage from wearing down. It may be a good fit if you are having your first ACL surgery at Peking University Third Hospital and your knee has already healed from the initial injury.
BeijingAges 18–40 - NCT06379308Recruiting
ACL revision surgery study in France
This study looks at people who need a second ACL surgery (revision). It helps doctors learn more about these procedures to improve care.
Saint-EtienneAges 18 years+ - NCT06430775Recruiting
Long-term ACL recovery after surgery
This study is looking at how well the ACL heals after surgery in the long term. It helps researchers understand recovery patterns, so you may get a closer look at your knee's healing process.
Roeselare, West-VlaanderenAges 18–40 - NCT06505525Recruiting
ACL reconstruction: adding extra support vs standard surgery
This trial compares two surgical techniques for ACL reconstruction. The standard method repairs the ACL inside the knee joint, while the new method also adds extra support outside the joint. The study aims to see which approach gives better stability and recovery for people with specific risk factors, like being a young athlete or having a chronic ACL tear.
São Paulo, São PauloAges 14–40 - NCT06511232RecruitingPhase 4
Morphine in bone for ACL surgery pain
This trial tests if giving morphine directly into the bone during ACL reconstruction can reduce pain after surgery. It may help patients who are having a specific type of ACL repair using their own patellar tendon.
Houston, TexasAges 18–40 - NCT06594497Recruiting
Mental practice for athletes with ACL repair
This study tests if motor imagery training (mentally practicing movements) helps football players recover after anterior cruciate ligament (ACL) repair surgery. It might improve muscle control and confidence without doing physical exercise.
KütahyaAges 18–30
Hear when a new Anterior Cruciate Ligament trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for anterior cruciate ligament?
- Yes. Clin2 currently lists 152 recruiting anterior cruciate ligament studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament (ACL) Reconstruction
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.