Clinical trials
Antibiotic Treatment clinical trials
Below are recruiting antibiotic treatment clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06921213RecruitingPhase 2
Oral antibiotics for newborns exposed to syphilis
This study tests whether giving oral antibiotics at home is as safe and effective as the usual injections for newborns exposed to syphilis during pregnancy. It is for babies who appear healthy at birth.
JakartaAges birth–1 week - NCT06728072RecruitingPhase 2
Adding antibiotics to first chemo for advanced colorectal cancer
This trial tests whether adding a short course of antibiotics to your standard first chemotherapy for stage 4 colorectal cancer can improve treatment. The antibiotics target certain gut bacteria that might affect how well the chemo works.
Richmond, VirginiaAges 18 years+ - NCT06870409RecruitingPhase 3
Phages plus antibiotics for heart infection treatment
This trial tests if adding bacteriophages (viruses that kill bacteria) to standard antibiotic treatment can help people with a serious heart valve infection called infective endocarditis. It may offer a new way to fight the infection.
MoscowAges 18 years+ - NCT07001618RecruitingPhase 2
Fecal transplant with immunotherapy for advanced lung cancer
This trial tests whether taking an oral fecal transplant (MaaT033) along with the immunotherapy drug cemiplimab can help people whose lung cancer stopped responding after antibiotics. It's for people with advanced non-small cell lung cancer whose cancer got worse after standard immunotherapy.
DijonAges 18 years+ - NCT06976125Recruiting
Using a model to guide antibiotic choice for UTI after ER visit
This trial tests whether a prediction model can help doctors choose the right antibiotic for women with a urinary tract infection (UTI) after an emergency room visit. It aims to improve treatment and reduce unnecessary antibiotics.
Cleveland, OhioAges 18 years+ - NCT06793137RecruitingPhase 2
Antibiotics before surgery for advanced rectal cancer
This trial tests if taking antibiotics before standard treatment can improve outcomes for people with advanced rectal cancer that requires surgery.
São Paulo, São PauloAges 18 years+ - NCT06517264Enrolling by invitation
Treating mild diverticulitis without antibiotics as an outpatient
This trial tests if mild diverticulitis (a small infection in the colon) can be safely treated at home without antibiotics. If you have this condition and are otherwise healthy, you may be able to avoid a hospital stay.
MurciaAges 18–80 - NCT06588010RecruitingPhase 3
Testing OM-89 to reduce antibiotic use for UTIs in neurogenic bladder
This trial tests whether a medication called OM-89 (a bacterial extract taken by mouth) can help reduce how often you need antibiotics for urinary tract infections (UTIs). It is for people with a neurogenic bladder from a spinal cord injury who use a catheter to empty their bladder and have had many UTIs in the past year.
DijonAges 18 years+ - NCT06952998RecruitingPhase 4
Platelet-rich plasma for diabetic foot ulcers with artery disease
This trial tests if a special treatment made from your own blood (platelet-rich plasma) can help heal foot ulcers in people with diabetes and poor circulation in their legs. The goal is to see if it improves wound healing compared to standard care.
Bilbao, BizkaiaAges 18 years+ - NCT05926063RecruitingPhase 4
Stopping antibiotics after 3 days for high-risk neutropenia
This study tests whether it is safe to stop broad antibiotics after 3 days in people at high risk of infection from low white blood cells (neutropenia) who are hospitalized with fever. It may reduce antibiotic exposure, while still watching closely to keep you safe.
Leuven, Vlaams-BrabantAges 16 years+ - NCT07214311RecruitingPhase 2/Phase 3
A trial of PLG0206 to prevent knee joint infection after surgery
This trial tests if a new drug called PLG0206 can stop a knee joint infection from coming back after a surgery called DAIR. DAIR cleans the infected area and keeps the artificial knee in place, and this study wants to see if adding PLG0206 helps prevent the infection from returning.
Sarasota, FloridaAges 18–80 - NCT07077122Recruiting
Comparing five gum disease treatments
This trial tests five different non-surgical gum treatments to see how they affect overall health. It may be a good fit for people with advanced gum disease who do not smoke heavily or take certain medications.
AthensAges Any age - NCT05224401RecruitingPhase 3
Oral antibiotic step-down for ESBL bladder infections
This Phase 3 trial tests whether switching from short-term IV antibiotics to an oral antibiotic combo is safe and effective for ESBL urine infections. It may help you avoid staying on IV antibiotics as long, if your bacteria are the right match.
HelsingborgAges 18–130 - NCT05202964Recruiting
Study comfort and safety with oral antibiotics for bone joint infection
This trial studies how tolerable (comfortable) and safe oral antibiotic treatment is for infections in bones or joints. It may help confirm whether taking antibiotics by mouth for at least 6 weeks is well tolerated during treatment.
LyonAges 18 years+ - NCT07777783Recruiting
Non-surgical treatment for breast abscess
This study tests whether draining a breast abscess with a needle and using antibiotics can treat it without surgery. It may be a gentler option for women with this condition.
SohagAges 18 years+ - NCT05640336Enrolling by invitation
Antibiotics for early knee or hip joint infections after surgery
This study compares two antibiotic plans for acute (early) infections around an artificial knee or hip, using a procedure to clean the joint and try to keep the implant. It may help find the best approach to control infection and then prevent it from coming back with longer-term antibiotic treatment.
Jacksonville, FloridaAges 18 years+ - NCT07198919Enrolling by invitationPhase 1/Phase 2
Pain relief during root canal for infected tooth: gel vs. antibiotic paste
This trial compares two medicines placed inside a tooth after root canal cleaning to see which reduces pain better between appointments. If you have an infected single-root tooth and are between 16-45 years old, you may be able to join.
Karachi, SindhAges 16–45 - NCT05925309Recruiting
Oral antibiotics to prevent bile duct inflammation after Kasai surgery
This trial studies whether giving oral antibiotics before symptoms start can lower the chance of cholangitis (bile duct infection/inflammation) after Kasai portoenterostomy. It may help protect your child’s bile flow and reduce painful or serious infections after surgery.
Shanghai, Shanghai MunicipalityAges 2 weeks–3 months - NCT06410443Recruiting
Steroid treatment for radiation-induced bowel injury
This trial tests if local steroids can help heal bowel damage caused by radiation therapy for cancer. It may reduce pain, bleeding, and urgency, and improve quality of life.
Shenyang, LiaoningAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05548283RecruitingPhase 4
Standard IV antibiotic timing for cystic fibrosis lung flare-ups
This study standardizes how IV aminoglycoside antibiotics are given during a 14-day treatment for cystic fibrosis (CF) lung flare-ups. It may help make treatment more consistent and easier to manage for people who need IV antibiotics.
Birmingham, AlabamaAges 6 years+ - NCT04722978RecruitingPhase 3
Chemo plus moxifloxacin for metastatic triple-negative breast cancer
This trial tests whether adding moxifloxacin (an antibiotic) to standard chemotherapy helps people with metastatic triple-negative breast cancer live longer or respond better. You may qualify if your cancer has the right lab markers and you haven’t had treatment for metastatic disease yet.
Guangzhou, GuangdongAges 18–70 - NCT07176247Enrolling by invitation
Study of aztreonam-avibactam for drug-resistant infections
This trial studies a combination antibiotic called aztreonam-avibactam for treating infections caused by hard-to-treat bacteria, especially those that produce certain enzymes (MBLs). It aims to see how well this medicine works in hospital patients.
ParisAges Any age
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Common questions
- Are there clinical trials for antibiotic treatment?
- Yes. Clin2 currently lists 71 recruiting antibiotic treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a antibiotic treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a antibiotic treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.