Clinical trials
Antibiotics clinical trials
Below are recruiting antibiotics clinical trials, each written for real people, not researchers. We’re tracking 283 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06219135Recruiting
Testing a new method to find infection germs and best antibiotics
This trial is testing a new method (IDBIORIV) to quickly identify the germs causing sepsis and find the right antibiotic. It aims to help patients with a confirmed bloodstream infection get the most effective treatment faster.
BronAges 1 day+ - NCT06100614Recruiting
Using a blood test to reduce antibiotics in preterm newborns
This study checks if a blood test (presepsin) can help doctors safely stop antibiotics earlier in preterm babies at moderate risk of infection. The goal is to reduce unnecessary antibiotic use.
Amsterdam, North HollandAges Any age - NCT06148025RecruitingPhase 4
Antibiotics and vaccine response study
This study looks at whether taking a short course of antibiotics changes how well vaccines work. You would receive the BCG vaccine (for tuberculosis) and possibly the yellow fever vaccine, and we would check your immune response over several months.
Adelaide, South AustraliaAges 18–35 - NCT06114706Recruiting
Better assessment of sore throat and antibiotic use
This study tests a new way to assess sore throats in primary care and pharmacies to help decide when antibiotics are needed. It aims to improve treatment and reduce unnecessary antibiotic use.
StenungsundAges 6 years+ - NCT05846399RecruitingPhase 4
Test antibiotic prevention after a cat bite to the hand
This study tests whether taking a specific antibiotic right after a cat bite to the hand or forearm can help prevent an infection. You may be eligible if you arrive within 24 hours and don’t already have signs of infection.
Columbia, MissouriAges 18 years+ - NCT06126731RecruitingPhase 1/Phase 2
Antibiotics plus enzalutamide for advanced prostate cancer
This trial tests whether adding specific antibiotics (amoxicillin, metronidazole, vancomycin, ciprofloxacin) to enzalutamide can help treat advanced prostate cancer that has stopped responding to other treatments. It aims to see if changing gut bacteria can make the cancer therapy work better.
BellinzonaAges 18 years+ - NCT06058819Recruiting
New blood test to guide antibiotic use in newborns
This study is testing a new blood test to see if it can help doctors decide when to use antibiotics for newborns who may have a late-onset infection. The goal is to reduce unnecessary antibiotic use.
BronAges 1 week–2 weeks - NCT06076304RecruitingPhase 4
Comparing treatments for acute sinusitis
This trial tests whether nasal steroids, nasal irrigation, or oral antibiotics work best for acute sinusitis. It may help if you have ongoing sinus symptoms or a 'double-sickening' pattern after a cold.
Los Angeles, CaliforniaAges 18–75 - NCT06055712Enrolling by invitationPhase 4
Antibiotics for children with open fractures
This trial tests whether giving antibiotics can prevent infections in children with mild open fractures (grade 1 or 2) that don't need surgery. It aims to find a safer, simpler treatment plan.
St Louis, MissouriAges birth–17 years - NCT04335383Recruiting
Study blood antibodies for a Pseudomonas-targeting treatment
This study looks at people’s blood to see if they already have antibodies that recognize Pseudomonas aeruginosa, a type of bacteria. If you qualify for the prospective part, they may collect blood samples at Grenoble University Hospital and use your results to support future treatment testing.
GrenobleAges 18 years+ - NCT05852158RecruitingPhase 4
Antibiotics to prevent infection after jaw surgery
This trial tests whether giving antibiotics can lower the chance of infection after orthognathic (jaw) surgery. It may help by preventing post-surgery infections, but participation depends on your health history and medication allergies.
Halifax, Nova ScotiaAges 16 years+ - NCT05835206RecruitingPhase 2
Drug to reduce antibiotic-resistant gut bacteria
This Phase 2 study tests whether an investigational treatment can help clear or reduce antibiotic-resistant bacteria living in the gut. It may help prevent these germs from causing future infections by targeting specific resistant bacteria found on stool or rectal swabs.
Atlanta, GeorgiaAges 18 years+ - NCT05777603RecruitingPhase 1
Aerosol antibiotics plus pembrolizumab for advanced lung cancer
This trial studies whether inhaled (aerosol) antibiotics combined with pembrolizumab can help people with advanced non-small cell lung cancer that has grown despite standard first treatment. It aims to improve cancer control by testing this new combination in Phase 1 safety and early effectiveness.
Bethesda, MarylandAges 18–120 - NCT05766670RecruitingPhase 3
Calcium and antibiotic placed inside tibia nail for open fractures
This Phase 3 study tests whether a calcium/antibiotic “depot” released from an intramedullary nail can lower infection risk in certain open tibia fractures. It may help by delivering antibiotics right at the fracture area while the nail fixes the bone.
Los Angeles, CaliforniaAges 18 years+ - NCT05761080RecruitingPhase 4
Faster recovery care for children with complicated appendicitis
This study tests a faster recovery plan for children who had surgery for complicated appendicitis. It aims to see if children can leave the hospital sooner and recover well at home with oral antibiotics instead of staying longer in the hospital.
Barcelona, BarcelonaAges 2–17 - NCT05206500RecruitingPhase 4
Test whether urine genetic testing changes care
This study looks at whether next-generation DNA testing from your urine can help doctors make better decisions about your treatment. You may be asked to return for follow-up visits so researchers can compare outcomes over time.
Winston-Salem, North CarolinaAges 18–80 - NCT05571722RecruitingPhase 4
Antibiotic prevention for surgical site infections
This trial tests whether using linezolid or vancomycin before surgery can better prevent infections at the surgical wound in people at higher risk. You might be considered because you either can’t take certain standard antibiotics (beta-lactams) and/or may carry MRSA bacteria.
MarseilleAges 18 years+ - NCT05584007RecruitingPhase 3
Choosing the best antibiotic length for leg cellulitis
This Phase 3 study compares 5 days versus 7 days of antibiotic treatment for new leg cellulitis (skin infection). It may help you get the right treatment duration while keeping side effects and recovery in mind.
SouthamptonAges 18 years+ - NCT05548283RecruitingPhase 4
Standard IV antibiotic timing for cystic fibrosis lung flare-ups
This study standardizes how IV aminoglycoside antibiotics are given during a 14-day treatment for cystic fibrosis (CF) lung flare-ups. It may help make treatment more consistent and easier to manage for people who need IV antibiotics.
Birmingham, AlabamaAges 6 years+ - NCT04722978RecruitingPhase 3
Chemo plus moxifloxacin for metastatic triple-negative breast cancer
This trial tests whether adding moxifloxacin (an antibiotic) to standard chemotherapy helps people with metastatic triple-negative breast cancer live longer or respond better. You may qualify if your cancer has the right lab markers and you haven’t had treatment for metastatic disease yet.
Guangzhou, GuangdongAges 18–70 - NCT05405491Recruiting
DNA test to guide antibiotic use for pneumonia in ICU patients
This study tests whether using a DNA test on lung fluid can help doctors choose better antibiotics for pneumonia in ICU patients with weakened immune systems. It may lead to more effective treatment and fewer side effects.
LilleAges 18 years+ - NCT05361941Recruiting
Antibiotic graft to help bone regrow in infected knee surgery areas
This trial tests an antibiotic “graft” placed into or near infected bone cavities around a knee replacement (TKA) to help new bone grow. You may be considered if you have an infected knee implant area and can safely take part in follow-up visits and treatment.
Los Angeles, CaliforniaAges 22 years+ - NCT05337566Recruiting
Extra antibiotic before hysterectomy to prevent infections
This trial tests whether giving extra antibiotic (azithromycin) before hysterectomy can lower the chance of infections after surgery. You might benefit by helping prevent post-surgery infection, but it also depends on your allergy history and heart rhythm risks.
HelsinkiAges 18 years+ - NCT05350813Recruiting
Using procalcitonin to stop antibiotics earlier safely
This study tests whether a blood test called procalcitonin can help doctors stop intravenous antibiotics earlier in young hospitalized children when an infection seems likely. The goal is to reduce unnecessary antibiotic exposure without missing serious infections.
AmiensAges 3 days–17 years
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Common questions
- Are there clinical trials for antibiotics?
- Yes. Clin2 currently lists 283 recruiting antibiotics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a antibiotics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a antibiotics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.