Clinical trials
Antibiotics clinical trials
Below are recruiting antibiotics clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05302531RecruitingPhase 1
Testing high-absorption antibiotics for short-bowel syndrome
This early (Phase 1) study tests how well certain antibiotics get absorbed in the body when you have short-bowel syndrome. It may help doctors choose antibiotics that work better through the mouth for people with this digestion problem.
Vandœuvre-lès-Nancy, LorraineAges 18 years+ - NCT05337566Recruiting
Extra antibiotic before hysterectomy to prevent infections
This trial tests whether giving extra antibiotic (azithromycin) before hysterectomy can lower the chance of infections after surgery. You might benefit by helping prevent post-surgery infection, but it also depends on your allergy history and heart rhythm risks.
HelsinkiAges 18 years+ - NCT05420935Recruiting
Study of antibodies after operating-room allergic reactions
This study looks at different kinds of allergy-related antibodies in people who had an allergic reaction during surgery. The goal is to better understand what immune signals are involved so future allergy prevention and care can improve.
Paris, ParisAges 18–70 - NCT05502913RecruitingPhase 2
Fecal transplant plus cancer immunotherapy for lung cancer
This trial studies whether giving a fecal microbiota transplant (a stool-based sample from a carefully screened donor) alongside immune checkpoint inhibitors can improve outcomes in people with lung cancer. It aims to change the gut bacteria to help the immune system work better against the cancer.
BeershebaAges 18 years+ - NCT05584007RecruitingPhase 3
Choosing the best antibiotic length for leg cellulitis
This Phase 3 study compares 5 days versus 7 days of antibiotic treatment for new leg cellulitis (skin infection). It may help you get the right treatment duration while keeping side effects and recovery in mind.
SouthamptonAges 18 years+ - NCT05678621RecruitingPhase 2/Phase 3
Testing stopping or extending immune treatment to prevent infections
This trial studies whether people with certain blood cancers can safely stop their immune support medicine (immunoglobulin, also called Ig) or whether they should continue. It also tests antibiotic prevention strategies to reduce the risk of serious infections.
Garran, Australian Capital TerritoryAges 18 years+ - NCT05681442RecruitingPhase 4
Antibiotics given in different ways for hospital sepsis
This study tests whether giving certain antibiotics intermittently versus continuously, along with a second antibiotic, works better for hospital-acquired sepsis. It may help doctors choose the most effective way to control serious infections.
AmiensAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05766670RecruitingPhase 3
Calcium and antibiotic placed inside tibia nail for open fractures
This Phase 3 study tests whether a calcium/antibiotic “depot” released from an intramedullary nail can lower infection risk in certain open tibia fractures. It may help by delivering antibiotics right at the fracture area while the nail fixes the bone.
Los Angeles, CaliforniaAges 18 years+ - NCT05784311RecruitingPhase 4
Longer vs shorter antibiotic prevention after pancreatoduodenectomy
This trial compares a standard length of preventive antibiotics versus a longer course after Whipple surgery to see if it lowers infection risk without causing extra side effects. It targets people considered higher risk for contamination of bile during surgery.
Leiden, South HollandAges 18–90 - NCT05791396RecruitingPhase 1/Phase 2
Fecal microbiome therapy to clear hard-to-treat gut germs
This trial looks at a treatment made from stool donors (called fecal microbiome therapy) to help remove carbapenem-resistant gut bacteria in the body. It’s mainly for adults who recently tested positive for these bacteria on a rectal swab, and it checks whether the therapy can help eradicate the germs.
RomaAges 18–85 - NCT05835206RecruitingPhase 2
Drug to reduce antibiotic-resistant gut bacteria
This Phase 2 study tests whether an investigational treatment can help clear or reduce antibiotic-resistant bacteria living in the gut. It may help prevent these germs from causing future infections by targeting specific resistant bacteria found on stool or rectal swabs.
Atlanta, GeorgiaAges 18 years+ - NCT05846399RecruitingPhase 4
Test antibiotic prevention after a cat bite to the hand
This study tests whether taking a specific antibiotic right after a cat bite to the hand or forearm can help prevent an infection. You may be eligible if you arrive within 24 hours and don’t already have signs of infection.
Columbia, MissouriAges 18 years+ - NCT05847322Recruiting
Pertussis challenge study with delayed antibiotic treatment
This study tests how well a “delayed antibiotic” plan works after being intentionally exposed to pertussis (whooping cough). It aims to learn whether delaying antibiotics for a short time is safe and useful, and you may be treated with an antibiotic if you become symptomatic.
Southampton, HampshireAges 18–55 - NCT05852158RecruitingPhase 4
Antibiotics to prevent infection after jaw surgery
This trial tests whether giving antibiotics can lower the chance of infection after orthognathic (jaw) surgery. It may help by preventing post-surgery infections, but participation depends on your health history and medication allergies.
Halifax, Nova ScotiaAges 16 years+ - NCT05876598Recruiting
Predict bloodstream infection risk using a computer model
This study builds and tests a computer (machine-learning) model to predict bloodstream infections based on what happens in the first days of care. It may help doctors start the right antibiotic faster for patients who truly have an infection.
RomeAges 18 years+ - NCT05926063RecruitingPhase 4
Stopping antibiotics after 3 days for high-risk neutropenia
This study tests whether it is safe to stop broad antibiotics after 3 days in people at high risk of infection from low white blood cells (neutropenia) who are hospitalized with fever. It may reduce antibiotic exposure, while still watching closely to keep you safe.
Leuven, Vlaams-BrabantAges 16 years+ - NCT05989152Recruiting
PET scan to check heart valve infection after antibiotics
This trial uses FDG-PET scans to see if a heart valve infection (endocarditis) is cured after antibiotics. It is for people with a prosthetic valve who had an active infection and a specific PET scan early in treatment.
Paris, FranceAges 18 years+ - NCT06018792Recruiting
New blood test for faster sepsis diagnosis in children
This trial tests a new, faster way to find bacteria in the blood of children with suspected sepsis. It uses a molecular test that may give results sooner than standard cultures, helping doctors treat infections more quickly.
AmsterdamAges birth–18 years - NCT06034080Recruiting
Cutting down unneeded antibiotics for children's ear infections
This study tests ways to help doctors avoid prescribing antibiotics when they are not needed for children with ear infections. If you are a parent of a child diagnosed with an ear infection or a healthcare provider, you may be able to join different parts of the study.
Denver, ColoradoAges 6 months–17 years - NCT06058819Recruiting
New blood test to guide antibiotic use in newborns
This study is testing a new blood test to see if it can help doctors decide when to use antibiotics for newborns who may have a late-onset infection. The goal is to reduce unnecessary antibiotic use.
BronAges 1 week–2 weeks - NCT06076304RecruitingPhase 4
Comparing treatments for acute sinusitis
This trial tests whether nasal steroids, nasal irrigation, or oral antibiotics work best for acute sinusitis. It may help if you have ongoing sinus symptoms or a 'double-sickening' pattern after a cold.
Los Angeles, CaliforniaAges 18–75 - NCT06100614Recruiting
Using a blood test to reduce antibiotics in preterm newborns
This study checks if a blood test (presepsin) can help doctors safely stop antibiotics earlier in preterm babies at moderate risk of infection. The goal is to reduce unnecessary antibiotic use.
Amsterdam, North HollandAges Any age - NCT06114706Recruiting
Better assessment of sore throat and antibiotic use
This study tests a new way to assess sore throats in primary care and pharmacies to help decide when antibiotics are needed. It aims to improve treatment and reduce unnecessary antibiotic use.
StenungsundAges 6 years+
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Common questions
- Are there clinical trials for antibiotics?
- Yes. Clin2 currently lists 296 recruiting antibiotics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a antibiotics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a antibiotics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.