Clinical trials
Aortic Stenosis clinical trials
Below are recruiting aortic stenosis clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03143361Recruiting
Aortic valve replacement registry for adults needing valve surgery
This study follows adults who are having aortic valve replacement to better understand outcomes across different hospitals in Europe. It may help your care team compare results and improve future treatment planning.
VeronaAges 18 years+ - NCT04613193Recruiting
Lower blood pressure to study outcomes in mild valve narrowing
This trial studies whether lowering blood pressure affects health outcomes in people who have valve narrowing in the heart but no valve symptoms yet. It may help you understand which blood pressure targets are safest when the aortic valve is not fully opening.
AarhusAges 18 years+ - NCT04703699Recruiting
Study of a heart valve implant after 30 days
This study looks at people who already received the Myval THV heart valve implant for severe native aortic valve narrowing. It checks how patients are doing after at least 30 days of follow-up to better understand the valve’s performance.
TallinnAges 18 years+ - NCT04882488Recruiting
Testing heart scan measurements in severe aortic valve narrowing
This trial compares two pressure-based measurements of blood flow in the coronary arteries with a PET heart scan in people with severe aortic valve stenosis. It may help doctors choose the most accurate way to assess blood flow and guide care during valve treatment.
Bad Oeynhausen, North Rhine-WestphaliaAges 65 years+ - NCT05711186Recruiting
Shared decision support for aortic valve procedures
This trial tests a structured, team-guided conversation to help you choose between two common valve procedures: SAVR (surgery) or TAVR (a less invasive procedure done through the groin). It may help you make a choice that fits your health goals and preferences.
BernAges 70 years+ - NCT05778773Recruiting
Study of treatment outcomes for severe aortic valve narrowing
This study looks at how well current treatment choices work for older adults with severe aortic valve narrowing (stenosis). It may help doctors better understand what works best for aging patients in Italy.
San Donato Milanese, MIAges 65 years+ - NCT06713889Recruiting
Study of heart valve disease and events
This study looks for biological markers in the blood that might help predict heart-related events in people with a narrowed aortic heart valve. It aims to improve care for those with this condition, whether or not they have a procedure called TAVI to replace the valve.
LyonAges 18 years+ - NCT07284550Recruiting
Smartphone screening for aortic valve stenosis
This study tests if a smartphone app can detect aortic valve stenosis (a heart valve condition) by recording heart sounds. If successful, it could offer a simple, non-invasive way to screen for this condition without a doctor's visit.
InnsbruckAges 18 years+ - NCT02856620Recruiting
Study heart function and frailty in people with aortic valve narrowing
This study looks at how heart mechanics, blood markers, and frailty relate to symptoms and heart measurements in people with aortic stenosis (a stiff, narrowed heart valve). It may help doctors better understand who is at higher risk and how disease changes over time.
Montreal, QuebecAges 18 years+ - NCT06743568Recruiting
Comparing new valves for tight aortic valve in enlarged aorta
This trial tests two types of replacement heart valves (self-expanding and balloon-expanding) in people who have severe aortic stenosis (tight heart valve) and an enlarged aorta (the main blood vessel from the heart). The goal is to see which valve type works better for these patients.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06518681Enrolling by invitation
Testing a new polymer heart valve for aortic disease
This trial tests a new type of artificial heart valve made of polymer (a special plastic-like material) for people with severe aortic valve disease. It aims to see if the valve is safe and works well, giving you an option for a replacement valve that might last longer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07566624Recruiting
Registry study of Hydra heart valve replacement procedure
This study tracks patients who receive a Hydra artificial heart valve to replace a severely narrowed aortic valve. Researchers will follow your progress to understand how well the device works and its safety in real-world use.
Fuencarral-El PardoAges 18 years+ - NCT05629104Recruiting
Predicting long-term outcomes after aortic valve procedure
This study follows people who have aortic valve treatment to better predict how they will do in the long term. It may help doctors understand what outcomes to expect after the procedure and improve future care.
UppsalaAges 18 years+ - NCT06337227Recruiting
Studying sirtuins as biomarkers for artery or heart valve disease
This study tests whether proteins called sirtuins can be used as biomarkers (biological clues) to better understand patients with hardened arteries (atherosclerosis) or calcified heart valve disease (calcific aortic stenosis), especially if you also have diabetes. It may help doctors develop better ways to diagnose or monitor these conditions.
NaplesAges 18 years+ - NCT06580158Recruiting
AI for diagnosing heart valve and pump problems
This trial is testing how well an AI tool can help doctors diagnose aortic stenosis and diastolic dysfunction by analyzing your scheduled ECG (heart test). The study takes place during your routine care at the clinic.
Rochester, MinnesotaAges 60 years+ - NCT03268135Recruiting
Study gene activity in people with heart failure or aortic stenosis
This trial looks at patterns in your blood or heart-related “gene activity” (transcriptome) after heart procedures. It may help doctors understand why some people with heart failure or aortic valve narrowing (stenosis) do better than others.
San Donato Milanese, MilanAges 40–75 - NCT06863883Recruiting
Aortic stenosis study: looking at outcomes after TAVI
This study follows people with aortic stenosis who are getting a TAVI valve replacement. It uses imaging tests (MRI and CT) to learn more about the condition and improve future care.
GothenburgAges Any age - NCT05603520Recruiting
Study of how the aorta varies in healthy people and patients
This study uses MRI scans to understand how different parts of the aorta look and behave, including in healthy volunteers and people with aortic problems. It may help researchers better describe differences in the aorta that could improve future diagnosis or treatment planning.
DüsseldorfAges 18 years+ - NCT06953206Recruiting
Long-term study of a new heart valve for aortic stenosis
This study is testing a new heart valve called the SAPIEN 3 Ultra RESILIA valve for people with severe aortic stenosis. Researchers want to see how well it works and how safe it is over 10 years after a minimally invasive valve replacement procedure called TAVI.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT06595992Recruiting
Observing moderate aortic valve disease over time
This study follows people with moderate aortic valve disease to learn how their condition changes. It does not test a new treatment but will help doctors better understand the disease.
Hangzhou, ZhejiangAges 18 years+ - NCT05930899Recruiting
Study tissue and blood samples from heart disease patients
This study builds a biobank, meaning it collects and stores your health information, blood, and possibly heart-related samples to help researchers learn why heart conditions happen. You might join if you have certain heart diagnoses and are having cardiac surgery for a problem other than an aortic valve issue.
Montreal, QuebecAges 19 years+ - NCT07709858Recruiting
Outcomes after TAVR for severe aortic valve disease
This is a registry study that tracks how people do after a TAVR procedure for a severely narrowed aortic heart valve. It helps doctors learn more about long-term outcomes and improve care for future patients.
SeoulAges 18 years+ - NCT04076150Recruiting
Testing a new valve placed through a blood vessel
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
KrakowAges 70 years+ - NCT06047561Recruiting
Scottish Aortic Stenosis Imaging Study
This study looks at how aortic stenosis (a narrowing of the heart valve) changes over time using imaging and blood tests. It may help doctors better understand and treat this condition.
EdinburghAges 50 years+
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Common questions
- Are there clinical trials for aortic stenosis?
- Yes. Clin2 currently lists 208 recruiting aortic stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.