Clinical trials
Aortic Stenosis clinical trials
Below are recruiting aortic stenosis clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05493657Recruiting
Aspirin vs clopidogrel after TAVR valve procedure
This trial compares aspirin and clopidogrel (two blood-thinning medicines) after TAVR to see which is safer or more effective for preventing clots. You may be able to join if you recently had a TAVR for severe aortic valve narrowing and can follow the study plan.
SeoulAges 19 years+ - NCT05866640RecruitingEarly Phase 1
Testing a filter to reduce debris during TAVR
This early feasibility study tests a device filter system used during a TAVR procedure to help protect the brain and other organs from debris that can break free. It looks mainly at whether the filter can be safely placed and delivered as planned.
TbilisiAges 22 years+ - NCT06129799Recruiting
Exercise heart MRI for low-flow aortic stenosis
This trial uses a special heart MRI scan before and after exercise to study blood flow in people with a type of aortic stenosis where the heart's pumping function may be reduced. It could help doctors better understand how to treat this condition.
GöttingenAges 18 years+ - NCT06173115Recruiting
One vs two stitch devices for TAVR valve replacement
This study compares using one versus two special stitch devices to close the artery after a TAVR procedure. It helps doctors learn which way works better to prevent bleeding or complications.
Bengbu, AnhuiAges 65 years+ - NCT06470022Recruiting
Comparing two new heart valves for TAVI
This trial compares two newer types of heart valves (Evolut FX and Sapien 3 Ultra Resilia) used in a procedure called TAVI, which replaces a narrowed heart valve without open-heart surgery. It is for people who are good candidates for both valves and can have the procedure through a leg artery.
AarhusAges 18 years+ - NCT06508866Recruiting
Studying heart rhythm changes after TAVI procedure
This trial looks at how the heart's electrical system may change after TAVI, a procedure to replace a narrowed aortic valve. It aims to better understand these changes to improve care for future patients.
Rozzano, MilanoAges 18 years+ - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
La Jolla, CaliforniaAges Any age - NCT06756282Recruiting
Pacemaker use one year after TAVR
This study looks at people who need a permanent pacemaker after having a TAVR procedure (a type of heart valve replacement). It aims to see how many people still need the pacemaker one year later.
MontpellierAges Any age - NCT06828770Recruiting
Minima stent system long-term safety study
This study checks the safety of the Minima Stent System over time. It is for people who need a stent to keep their blood vessel open. The study wants to see how the device works in real-world use.
Los Angeles, CaliforniaAges Any age - NCT07006064Recruiting
Comparing oxygen methods during TAVI for older patients
This trial tests a new oxygen device (SuperNO2VA) against standard oxygen to prevent low oxygen levels in patients aged 65 and older who are getting a heart valve procedure (TAVI) while sedated. The goal is to see which method keeps oxygen levels safer.
AnkaraAges 65 years+ - NCT07035847Recruiting
Transaxillary TAVR guided by ultrasound only
This trial is testing a new way to replace your aortic valve using a small tube through your armpit, guided only by ultrasound (echocardiography) instead of X-rays. It may be an option if you have severe aortic stenosis and are a good fit for this less invasive approach.
Beijing, Beijing MunicipalityAges Any age - NCT07230964Recruiting
Heart valve study using a non-invasive skin test
This trial tests a special skin test (impedance cardiography) that may detect heart muscle changes in people with aortic stenosis. It could help doctors decide when valve replacement is needed.
Chicago, IllinoisAges 18 years+ - NCT07343674Recruiting
Studying a new heart valve replacement system for aortic stenosis
This trial is testing a new heart valve system (Medtronic Evolut FX+) for people with severe aortic stenosis—a condition where the heart's main valve is narrowed. The study aims to see how well the valve works and improve your care journey.
Coimbra, Coimbra DistrictAges 18 years+ - NCT07240025Enrolling by invitation
TAVR outcomes for small aortic valves in Asian patients
This study looks at how well a minimally invasive heart valve replacement (TAVR) works for Asian patients with a small aortic valve opening. It aims to understand what affects the results.
Hong Kong, ShatinAges Any age - NCT06911463Enrolling by invitation
Pain relief for TAVI valve procedure
This study tests two numbing injections for people having a new aortic valve placed through a leg artery (TAVI). One injection is near the hip bone, the other in the groin area. The goal is to see which one provides better pain control while keeping you awake and comfortable.
CairoAges 20 years+ - NCT06891079Enrolling by invitation
Guiding TAVI with a new angiographic method
This study tests a new way to use X-ray images during a TAVI procedure to check how well the new valve is working right away. It may help doctors make real-time adjustments to improve the outcome.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06049654Recruiting
Comparing Allegra and Sapien valves for valve-in-valve procedure
This trial tests two different replacement heart valves (Allegra and Sapien) to see which works better for people who need a new valve placed inside a previously implanted surgical valve. It aims to help patients with a failing biological aortic valve who are already scheduled for this procedure.
AlessandriaAges 18 years+ - NCT05309707Recruiting
Branched stents for certain aortic arch problems
This study looks at using special branched stent-grafts to treat problems in the aortic arch (such as aneurysm or certain tears). It focuses on how well this approach works and how patients do over follow-up visits.
MadridAges 18–90 - NCT07520656Recruiting
Heart Valve Surgery and Sleep Breathing Problems
This study looks at whether fixing heart valve problems with minimally invasive procedures (TAVI or MTEER) can improve sleep-related breathing issues. Researchers will monitor your sleep patterns before and after your scheduled heart valve procedure.
Athens, AtticaAges 18 years+ - NCT05862558Recruiting
Lithotripsy to open blocked, calcified artery for TAVR
This trial tests whether a treatment called intravascular lithotripsy (using sound waves from inside a blood vessel) can help widen severely calcified, narrowed iliac arteries so a TAVR procedure can be done through the groin. It may help some people who are considered “high risk” for access, based on CT scan findings.
Plano, TexasAges 18–90 - NCT07456280Recruiting
Early discharge after TAVI using heart monitoring
This study tests if patients who have mild heart electrical changes after TAVI can be sent home early with a portable heart monitor instead of staying in the hospital. It aims to see if this approach is safe and effective.
BarcelonaAges 18 years+ - NCT03470246Recruiting
Wearable activity coaching after heart surgery
This study tests a personalized activity program and coaching after heart surgery, using wearable sensors to track movement. It may help you recover more safely and move in a goal-directed way during rehabilitation.
KuopioAges 30–90 - NCT03549559Recruiting
Heart imaging study in healthy people and specific conditions
This study uses heart imaging to look at changes in the heart muscle. It includes healthy volunteers and people with diabetes or aortic stenosis, to understand differences seen on scans.
Boston, MassachusettsAges 18–85 - NCT04275726Recruiting
Myval heart valve study for adults needing TAVI
This trial studies whether the Myval THV (a new heart valve) is safe and effective for adults who need TAVI, a procedure to replace a narrowed heart valve without open-heart surgery. You may be considered if a heart team says you’re a good candidate for this valve procedure and you’re willing to join the study.
MinskAges 18 years+
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Common questions
- Are there clinical trials for aortic stenosis?
- Yes. Clin2 currently lists 208 recruiting aortic stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.