Clinical trials
Aortic Stenosis clinical trials
Below are recruiting aortic stenosis clinical trials, each written for real people, not researchers. We’re tracking 198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06828770Recruiting
Minima stent system long-term safety study
This study checks the safety of the Minima Stent System over time. It is for people who need a stent to keep their blood vessel open. The study wants to see how the device works in real-world use.
Los Angeles, CaliforniaAges Any age - NCT06833762Recruiting
Predicting improvement after TAVI using exercise tests
This trial looks at whether a simple exercise test (called CPET) can help predict how much your heart function will improve after TAVI, a procedure to replace a narrowed heart valve. If you're scheduled for TAVI through your leg artery and are 18 or older, you might be able to join.
BarcelonaAges 18 years+ - NCT05493657Recruiting
Aspirin vs clopidogrel after TAVR valve procedure
This trial compares aspirin and clopidogrel (two blood-thinning medicines) after TAVR to see which is safer or more effective for preventing clots. You may be able to join if you recently had a TAVR for severe aortic valve narrowing and can follow the study plan.
SeoulAges 19 years+ - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
La Jolla, CaliforniaAges Any age - NCT04234841Recruiting
Study of outcomes after aortic valve replacement
This study follows adults who are having aortic valve replacement (through surgery or a catheter) to see how often certain outcomes happen after the procedure. You may be asked for blood tests and scans at set times, and some people may also be offered a special CT scan.
Stevenage, HertforshireAges 18 years+ - NCT03628313Recruiting
Aortic Valve Narrowing: Long-term Outcomes Study
This study follows patients with aortic stenosis (a narrowing of the heart valve that controls blood flow from the heart) to understand how the condition progresses over time and what outcomes patients experience. By reviewing medical records and contacting patients for follow-up, researchers hope to better predict who is at higher risk and inform treatment decisions.
Amiens, FranceAges 18–100 - NCT06049654Recruiting
Comparing Allegra and Sapien valves for valve-in-valve procedure
This trial tests two different replacement heart valves (Allegra and Sapien) to see which works better for people who need a new valve placed inside a previously implanted surgical valve. It aims to help patients with a failing biological aortic valve who are already scheduled for this procedure.
AlessandriaAges 18 years+ - NCT05309707Recruiting
Branched stents for certain aortic arch problems
This study looks at using special branched stent-grafts to treat problems in the aortic arch (such as aneurysm or certain tears). It focuses on how well this approach works and how patients do over follow-up visits.
MadridAges 18–90 - NCT07520656Recruiting
Heart Valve Surgery and Sleep Breathing Problems
This study looks at whether fixing heart valve problems with minimally invasive procedures (TAVI or MTEER) can improve sleep-related breathing issues. Researchers will monitor your sleep patterns before and after your scheduled heart valve procedure.
Athens, AtticaAges 18 years+ - NCT03470246Recruiting
Wearable activity coaching after heart surgery
This study tests a personalized activity program and coaching after heart surgery, using wearable sensors to track movement. It may help you recover more safely and move in a goal-directed way during rehabilitation.
KuopioAges 30–90 - NCT05721170RecruitingPhase 4
Beta blockers after TAVI in high-risk adults with valve narrowing
This study tests whether stopping beta blockers after TAVI is safe and effective compared with continuing them. It may help clarify the best medication plan after valve replacement for people at higher surgical risk.
NicosiaAges 18 years+ - NCT07456280Recruiting
Early discharge after TAVI using heart monitoring
This study tests if patients who have mild heart electrical changes after TAVI can be sent home early with a portable heart monitor instead of staying in the hospital. It aims to see if this approach is safe and effective.
BarcelonaAges 18 years+ - NCT06804148Recruiting
Myval heart valve registry in Germany
This registry tracks people getting a new heart valve called Myval. It's designed to see how well it works in real-world care.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06917066Recruiting
Registry for severe aortic stenosis patients getting a specific TAVR valve
This study tracks patients with severe aortic stenosis who receive the Myval transcatheter heart valve during TAVR (a less-invasive valve replacement). It aims to understand how well the valve works over time.
Valladolid, ValladolidAges 18 years+ - NCT07205341Recruiting
Artery blood flow monitoring during heart valve procedure
This study is testing a new way to monitor blood flow and heart function during a valve replacement procedure. It may help doctors track how well the heart is pumping.
Boulder, ColoradoAges 18–80 - NCT07016477Recruiting
Heart CT study for TAVI planning
This study is a registry (a collection of information) for people who are about to have a TAVI heart valve procedure. It will see how a new type of CT scanner (the NAEOTOM Alpha) can help doctors plan the procedure better.
Charleston, South CarolinaAges 18 years+ - NCT06215378RecruitingPhase 3
Protamine Sulfate to Reverse Heparin After TAVI
This trial tests whether giving protamine sulfate after a TAVI procedure (aortic valve replacement through the leg) to reverse the blood thinner heparin is safe and effective. It may help reduce bleeding risk for patients.
Paris, Île-de-France RegionAges 18 years+ - NCT05552352Recruiting
VR training to help people prepare for aortic valve procedure
This trial tests whether virtual reality (VR) support helps patients feel more informed and prepared for an elective heart valve procedure (TAVI). It’s meant for people who already plan to have a valve replacement through the groin using a catheter, with pain medicines rather than full anesthesia.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT05862558Recruiting
Lithotripsy to open blocked, calcified artery for TAVR
This trial tests whether a treatment called intravascular lithotripsy (using sound waves from inside a blood vessel) can help widen severely calcified, narrowed iliac arteries so a TAVR procedure can be done through the groin. It may help some people who are considered “high risk” for access, based on CT scan findings.
Plano, TexasAges 18–90 - NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT03549559Recruiting
Heart imaging study in healthy people and specific conditions
This study uses heart imaging to look at changes in the heart muscle. It includes healthy volunteers and people with diabetes or aortic stenosis, to understand differences seen on scans.
Boston, MassachusettsAges 18–85 - NCT05308888RecruitingPhase 2
PET scan study of heart inflammation after aortic valve replacement
This Phase 2 trial uses a PET scan to study how local inflammation inside the heart affects the heart’s electrical wiring after a minimally invasive aortic valve procedure. The results may help doctors better predict or prevent rhythm and conduction problems after treatment.
BrestAges 18 years+ - NCT04275726Recruiting
Myval heart valve study for adults needing TAVI
This trial studies whether the Myval THV (a new heart valve) is safe and effective for adults who need TAVI, a procedure to replace a narrowed heart valve without open-heart surgery. You may be considered if a heart team says you’re a good candidate for this valve procedure and you’re willing to join the study.
MinskAges 18 years+ - NCT03303612Recruiting
Check monitoring vs guided pacing after valve replacement
This study compares two ways to decide when someone needs a pacemaker after they get a new heart valve (TAVI) and develop a new, persistent left bundle branch block (LBBB). It may help reduce unnecessary procedures while still keeping heart rhythms safe.
Edmonton, AlbertaAges 18 years+
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Common questions
- Are there clinical trials for aortic stenosis?
- Yes. Clin2 currently lists 198 recruiting aortic stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.