Clinical trials
Aortic Valve Stenosis clinical trials
Below are recruiting aortic valve stenosis clinical trials, each written for real people, not researchers. We’re tracking 217 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06101888Recruiting
New Heart Valve for Severe Aortic Leak
This study is testing a new, less invasive heart valve system (TaurusTrio) for people with severe aortic regurgitation (a leaky aortic valve) who cannot have open-heart surgery. It aims to see if the valve is safe and works well to improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04408430Recruiting
Valve replacement for severe mitral valve disease in high-risk adults
This trial tests a less-invasive way to treat severe mitral valve problems using a transcatheter valve. It may help people who are too high-risk for standard open-heart mitral surgery by improving symptoms and heart function.
Gilbert, ArizonaAges 18 years+ - NCT06518317RecruitingPhase 3
Short vs Long Blood Thinner Use After TAVI
This trial compares a short course versus a longer course of antiplatelet medicine (blood thinners) after a TAVI procedure for aortic stenosis. It aims to see which approach is safer and more effective.
CaenAges 18 years+ - NCT06833762Recruiting
Predicting improvement after TAVI using exercise tests
This trial looks at whether a simple exercise test (called CPET) can help predict how much your heart function will improve after TAVI, a procedure to replace a narrowed heart valve. If you're scheduled for TAVI through your leg artery and are 18 or older, you might be able to join.
BarcelonaAges 18 years+ - NCT07434193Recruiting
Pacing study after aortic valve replacement
This trial tests if special pacing of the heart's lower chambers (called cardiac resynchronization therapy, or CRT) can help people who develop a new electrical delay in the heart after having a transcatheter aortic valve replacement (TAVI). The study compares two types of pacing to see which works better for recovery.
BudapestAges 18 years+ - NCT04234841Recruiting
Study of outcomes after aortic valve replacement
This study follows adults who are having aortic valve replacement (through surgery or a catheter) to see how often certain outcomes happen after the procedure. You may be asked for blood tests and scans at set times, and some people may also be offered a special CT scan.
Stevenage, HertforshireAges 18 years+ - NCT03628313Recruiting
Aortic Valve Narrowing: Long-term Outcomes Study
This study follows patients with aortic stenosis (a narrowing of the heart valve that controls blood flow from the heart) to understand how the condition progresses over time and what outcomes patients experience. By reviewing medical records and contacting patients for follow-up, researchers hope to better predict who is at higher risk and inform treatment decisions.
Amiens, FranceAges 18–100 - NCT05093764Recruiting
Test how well debris is captured during valve-in-valve TAVR
This trial studies a device and a technique meant to capture debris during a repeat aortic valve procedure (valve-in-valve TAVR). It may help doctors understand if the approach reduces risk from material that can break loose during the procedure.
Kansas City, MissouriAges 18 years+ - NCT05493657Recruiting
Aspirin vs clopidogrel after TAVR valve procedure
This trial compares aspirin and clopidogrel (two blood-thinning medicines) after TAVR to see which is safer or more effective for preventing clots. You may be able to join if you recently had a TAVR for severe aortic valve narrowing and can follow the study plan.
SeoulAges 19 years+ - NCT05866640RecruitingEarly Phase 1
Testing a filter to reduce debris during TAVR
This early feasibility study tests a device filter system used during a TAVR procedure to help protect the brain and other organs from debris that can break free. It looks mainly at whether the filter can be safely placed and delivered as planned.
TbilisiAges 22 years+ - NCT06173115Recruiting
One vs two stitch devices for TAVR valve replacement
This study compares using one versus two special stitch devices to close the artery after a TAVR procedure. It helps doctors learn which way works better to prevent bleeding or complications.
Bengbu, AnhuiAges 65 years+ - NCT06470022Recruiting
Comparing two new heart valves for TAVI
This trial compares two newer types of heart valves (Evolut FX and Sapien 3 Ultra Resilia) used in a procedure called TAVI, which replaces a narrowed heart valve without open-heart surgery. It is for people who are good candidates for both valves and can have the procedure through a leg artery.
AarhusAges 18 years+ - NCT06508866Recruiting
Studying heart rhythm changes after TAVI procedure
This trial looks at how the heart's electrical system may change after TAVI, a procedure to replace a narrowed aortic valve. It aims to better understand these changes to improve care for future patients.
Rozzano, MilanoAges 18 years+ - NCT06559332Recruiting
Heart artery checks during aortic valve replacement
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
BernAges 70 years+ - NCT06657911Recruiting
Studying a new sizing method for bicuspid aortic valves
This trial looks back at people with a specific type of bicuspid aortic valve (a valve with two flaps instead of three) who had a transcatheter aortic valve replacement. Researchers want to see how well a special sizing method called LIRA worked for choosing the right valve size.
Brescia, ItalyAges 18 years+ - NCT07035847Recruiting
Transaxillary TAVR guided by ultrasound only
This trial is testing a new way to replace your aortic valve using a small tube through your armpit, guided only by ultrasound (echocardiography) instead of X-rays. It may be an option if you have severe aortic stenosis and are a good fit for this less invasive approach.
Beijing, Beijing MunicipalityAges Any age - NCT07230964Recruiting
Heart valve study using a non-invasive skin test
This trial tests a special skin test (impedance cardiography) that may detect heart muscle changes in people with aortic stenosis. It could help doctors decide when valve replacement is needed.
Chicago, IllinoisAges 18 years+ - NCT07343674Recruiting
Studying a new heart valve replacement system for aortic stenosis
This trial is testing a new heart valve system (Medtronic Evolut FX+) for people with severe aortic stenosis—a condition where the heart's main valve is narrowed. The study aims to see how well the valve works and improve your care journey.
Coimbra, Coimbra DistrictAges 18 years+ - NCT07521800Recruiting
Remote Heart Monitoring After Aortic Valve Replacement
This study tests whether monitoring your heart rhythm at home using a portable ECG device after your aortic valve replacement procedure (TAVI) helps catch problems early. Researchers want to see if remote monitoring is safe and helpful for patients recovering from this procedure.
TurinAges 18 years+ - NCT07648693Recruiting
Brain Protection Device During Aortic Valve Replacement
This trial tests a new device called CHORDS that protects your brain during transcatheter aortic valve replacement (TAVR), a minimally invasive procedure to fix a narrow aortic valve. The device works by blocking debris that might travel to your brain during the procedure.
Bengbu, AnhuiAges 18 years+ - NCT07240025Enrolling by invitation
TAVR outcomes for small aortic valves in Asian patients
This study looks at how well a minimally invasive heart valve replacement (TAVR) works for Asian patients with a small aortic valve opening. It aims to understand what affects the results.
Hong Kong, ShatinAges Any age - NCT07151989Enrolling by invitation
How valve disease type affects new valve durability
This study looks at people who had their mitral valve replaced to see if the original valve problem (tight vs leaky) affects how long the new valve lasts. It may help doctors understand which patients need closer follow-up.
Maastricht, MaastrichtAges 18 years+ - NCT06194526Enrolling by invitation
Blood test to measure heart artery plaque
This study is testing whether a new blood test can detect the amount of plaque buildup in your heart arteries compared to what a CT scan shows. It may help people with known or suspected coronary artery disease get a simpler, faster way to check their heart health.
Ciudad Autónoma de Buenos Aire, Buenos Aires F.D.Ages 18–75 - NCT07394998Recruiting
Exercise and Heart Health After Mitral Valve Treatment
This study looks at how well your heart and muscles work during exercise after a mitral valve procedure. It also checks stiffness of your main artery (aorta) and oxygen levels in your muscles.
Ankara, ÇankayaAges 18–80
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Common questions
- Are there clinical trials for aortic valve stenosis?
- Yes. Clin2 currently lists 217 recruiting aortic valve stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic valve stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic valve stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.