Clinical trials
Aortic Valve Stenosis clinical trials
Below are recruiting aortic valve stenosis clinical trials, each written for real people, not researchers. We’re tracking 217 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05862558Recruiting
Lithotripsy to open blocked, calcified artery for TAVR
This trial tests whether a treatment called intravascular lithotripsy (using sound waves from inside a blood vessel) can help widen severely calcified, narrowed iliac arteries so a TAVR procedure can be done through the groin. It may help some people who are considered “high risk” for access, based on CT scan findings.
Plano, TexasAges 18–90 - NCT07456280Recruiting
Early discharge after TAVI using heart monitoring
This study tests if patients who have mild heart electrical changes after TAVI can be sent home early with a portable heart monitor instead of staying in the hospital. It aims to see if this approach is safe and effective.
BarcelonaAges 18 years+ - NCT03549559Recruiting
Heart imaging study in healthy people and specific conditions
This study uses heart imaging to look at changes in the heart muscle. It includes healthy volunteers and people with diabetes or aortic stenosis, to understand differences seen on scans.
Boston, MassachusettsAges 18–85 - NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT05552352Recruiting
VR training to help people prepare for aortic valve procedure
This trial tests whether virtual reality (VR) support helps patients feel more informed and prepared for an elective heart valve procedure (TAVI). It’s meant for people who already plan to have a valve replacement through the groin using a catheter, with pain medicines rather than full anesthesia.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT05721170RecruitingPhase 4
Beta blockers after TAVI in high-risk adults with valve narrowing
This study tests whether stopping beta blockers after TAVI is safe and effective compared with continuing them. It may help clarify the best medication plan after valve replacement for people at higher surgical risk.
NicosiaAges 18 years+ - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
La Jolla, CaliforniaAges Any age - NCT06917066Recruiting
Registry for severe aortic stenosis patients getting a specific TAVR valve
This study tracks patients with severe aortic stenosis who receive the Myval transcatheter heart valve during TAVR (a less-invasive valve replacement). It aims to understand how well the valve works over time.
Valladolid, ValladolidAges 18 years+ - NCT07016477Recruiting
Heart CT study for TAVI planning
This study is a registry (a collection of information) for people who are about to have a TAVI heart valve procedure. It will see how a new type of CT scanner (the NAEOTOM Alpha) can help doctors plan the procedure better.
Charleston, South CarolinaAges 18 years+ - NCT07205341Recruiting
Artery blood flow monitoring during heart valve procedure
This study is testing a new way to monitor blood flow and heart function during a valve replacement procedure. It may help doctors track how well the heart is pumping.
Boulder, ColoradoAges 18–80 - NCT03303612Recruiting
Check monitoring vs guided pacing after valve replacement
This study compares two ways to decide when someone needs a pacemaker after they get a new heart valve (TAVI) and develop a new, persistent left bundle branch block (LBBB). It may help reduce unnecessary procedures while still keeping heart rhythms safe.
Edmonton, AlbertaAges 18 years+ - NCT06991517Recruiting
TAVR sizing study for bicuspid aortic valve patients
This study tests a special sizing method (ABC algorithm) to help doctors select the right valve for people with a bicuspid aortic valve. It aims to improve outcomes for those getting a Sapien 3 valve through a catheter (TAVR).
St Leonards, New South WalesAges Any age - NCT06863883Recruiting
Aortic stenosis study: looking at outcomes after TAVI
This study follows people with aortic stenosis who are getting a TAVI valve replacement. It uses imaging tests (MRI and CT) to learn more about the condition and improve future care.
GothenburgAges Any age - NCT07059728Recruiting
High flow oxygen during TAVR heart valve procedure
This trial tests whether using high-flow oxygen through the nose during a TAVR procedure helps keep oxygen levels stable. It may be an option for people having a planned, elective TAVR through the leg.
Barcelona, BarcelonaAges 18 years+ - NCT06047561Recruiting
Scottish Aortic Stenosis Imaging Study
This study looks at how aortic stenosis (a narrowing of the heart valve) changes over time using imaging and blood tests. It may help doctors better understand and treat this condition.
EdinburghAges 50 years+ - NCT06749145Enrolling by invitation
Using deep learning to find aortic stenosis earlier
This study tests if a deep learning tool can help detect aortic stenosis, a heart valve condition, in older adults during routine primary care visits. If you are 70 or older and have not had a recent echocardiogram, you may be able to join.
New Haven, ConnecticutAges 70 years+ - NCT06749132Enrolling by invitation
AI-powered monitoring for mild aortic valve disease
This study uses an artificial intelligence (AI) program to analyze past heart ultrasound images and predict if your aortic valve condition (mild thickening or narrowing) may get worse over time. The goal is to catch changes early and personalize your follow-up care.
New Haven, ConnecticutAges 65 years+ - NCT07309029Recruiting
ECMO support during high-risk TAVR heart valve procedure
This trial tests whether placing patients on ECMO (a heart-lung support machine) before a high-risk TAVR valve replacement can improve safety and outcomes. It is for people who are at very high risk due to low blood pressure, severe heart or lung problems, or complex valve anatomy.
Detroit, MichiganAges 18–100 - NCT07398911Enrolling by invitation
3D simulated TAVR for aortic valve leak
This trial tests whether a 3D computer simulation can help guide a less invasive procedure (TAVR) to replace a leaky aortic valve. It may be an option for people with severe aortic regurgitation who are at least 65 years old.
Xi’an, ShanxiAges 65 years+ - NCT07596394Recruiting
Registry of Catheter-Based Aortic Valve Replacements
This registry collects information about patients who receive a new valve inserted through a catheter (a thin tube) rather than open surgery. It tracks how well the procedure works and any side effects to help doctors understand the long-term safety and effectiveness of this less invasive approach.
Pavia, PaviaAges 18 years+ - NCT06816485Recruiting
New balloon safety in TAVI for severe aortic stenosis
This trial studies a new balloon used during a TAVI procedure to replace your aortic valve without open-heart surgery. It aims to see if the balloon is safe and works well for people with severe aortic stenosis.
BarcelonaAges 18 years+ - NCT06286358Recruiting
Heart and aorta imaging study for valve disease
This study uses a special recording device to see if heart and aorta problems can be detected earlier. It may help people with aortic valve disease or enlarged aorta decide on treatment.
BrusselsAges 18 years+ - NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT04552275RecruitingPhase 1
Biomarker study during valve replacement for older adults
This Phase 1 study looks at changes in the body’s “biomarkers” (measurable signs in blood/medical tests) in older people who are getting a specific type of valve replacement. Results may help doctors better monitor or understand outcomes after this valve procedure.
Boston, MassachusettsAges 65 years+
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Common questions
- Are there clinical trials for aortic valve stenosis?
- Yes. Clin2 currently lists 217 recruiting aortic valve stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic valve stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic valve stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.