Clinical trials
Back Pain clinical trials
Below are recruiting back pain clinical trials, each written for real people, not researchers. We’re tracking 395 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06704425Recruiting
How back pain affects thinking in older adults
This study looks at how chronic low back pain might affect memory, attention, and other thinking skills in adults aged 60 to 85. You will complete questionnaires, thinking tasks, and a brain scan to help researchers understand the link between pain and cognitive function.
Hong Kong, Hong KongAges 60–85 - NCT05706103Recruiting
Exercise therapy for recurrent low back pain with brain changes
This trial studies whether a specific exercise program can improve recurrent low back pain by changing activity in muscles and the brain. If you have non-specific low back pain that comes and goes over time, you may be asked to do exercises and undergo brain and muscle testing (including MRI).
Ghent, Oost-VlaanderenAges 18–45 - NCT07510789Recruiting
Low back pain impact in ankylosing spondylitis
This study looks at how different types of low back pain in people with ankylosing spondylitis affect their daily functioning and overall well-being. It aims to better understand these pain patterns so doctors can provide more personalized care.
Konya, SelçukluAges 18 years+ - NCT06771492RecruitingPhase 3
Antibiotics for chronic back pain with Modic changes
This trial tests whether an antibiotic (amoxicillin) can reduce chronic low back pain in people who have a specific type of bone change (Modic type I) after a past herniated disc. If you qualify, you would receive either the antibiotic or a placebo (inactive pill) for several weeks.
Rotterdam, South HollandAges 18–65 - NCT07134699Recruiting
Back pain's effect on thinking in older adults
This study looks at how long-term lower back pain affects thinking skills like memory and attention in adults aged 60 to 85. Participants must speak Cantonese, be right-handed, and have normal thinking abilities. The study uses email or text for some tasks.
Hong KongAges 60–85 - NCT06455423Enrolling by invitation
ELDOA and adjustments for upper back pain and posture
This study tests whether adding a gentle stretching technique (ELDOA) to standard upper back adjustments can improve upper back pain, reduce hunching, and correct forward head posture. It is for adults with upper back discomfort and postural issues.
Islamabad, FederalAges 19–44 - NCT06724679Recruiting
Virtual reality for chronic back pain treatment
This trial tests if using a virtual reality (VR) headset can help people with long-term lower back pain during a spine rehabilitation program. It will see if VR is a practical and helpful addition to the program.
AngersAges 18–65 - NCT07375914Recruiting
New approach for managing acute low back pain in the ER
This trial tests a comprehensive program that looks at your physical, mental, and social needs to treat sudden low back pain in the emergency room. It may help you get better care and avoid long-term pain.
ParisAges 18–55 - NCT06534593Enrolling by invitation
Physical therapy for low back pain from disc herniation
This trial tests whether physical therapy can help people with a specific type of disc herniation (postero-lateral) by improving pain, stability, walking, and daily function. It may be a good fit if you have low back pain that spreads to your leg or stays in your back.
Islamabad, FederalAges 18–50 - NCT06777771Recruiting
Reformer Pilates for first-time pregnant women
This trial tests if Reformer Pilates (a type of exercise using a special machine) helps first-time pregnant women stay healthy. If you are in your first pregnancy and between 11 and 22 weeks along, this may be a good fit for you.
Izmir, KonakAges 18–35 - NCT07632820RecruitingPhase 4
Nerve Block vs. Injection for Upper Back Muscle Pain
This study compares two ways to treat chronic muscle pain in the upper back: a nerve block (numbing injection near the spine) and trigger point injections (shots directly into painful muscle knots). The goal is to see which approach works better for long-lasting relief.
Jacksonville, FloridaAges 18–80 - NCT06771713Recruiting
Brief Pain Reprocessing Therapy for Veterans with Chronic Back Pain
This trial tests a type of talk therapy called Brief Pain Reprocessing Therapy for Veterans with long-term low back pain. The therapy is done over video calls, so you can join from home. It aims to help retrain how your brain processes pain signals.
Ann Arbor, MichiganAges 18 years+ - NCT05306665Recruiting
Preventing pain after spine surgery
This study looks at ways to reduce pain after certain spine surgeries. If you’re having one of these procedures, you may be invited to try a pain-prevention approach and help researchers understand what works best.
Chestnut Hill, MassachusettsAges 22 years+ - NCT06961396Recruiting
Virtual reality for period pain relief
This trial tests if using virtual reality can help reduce pain during menstruation in young women with primary dysmenorrhea (painful periods not caused by another condition). It may offer a drug-free option for managing period discomfort.
IsmailiaAges 13–20 - NCT07543692Recruiting
Ultrasound-guided injection therapy for spine pain
This study tests whether using ultrasound imaging to guide a special injection treatment (pharmacopuncture) is safe and effective for people with spine-related neck or lower back pain that radiates into the arms or legs. The treatment is already being offered as routine care, and this study tracks how well it works.
Daejeon, DaejeonAges 19–69 - NCT05009433Recruiting
Exercise plans in pregnancy and afterward for mom and baby health
This study compares two types of exercise—short, intense intervals versus moderate steady activity—during pregnancy and looks at effects on mothers and children. It also checks how participants do on health, fitness, and well-being tests before, during, and after pregnancy.
Gdansk, Pomeranian VoivodeshipAges 18–45 - NCT05023005Recruiting
Strain-Counterstrain therapy for piriformis muscle pain
This trial tests a hands-on physical therapy technique called “strain-counterstrain” to reduce pain from the piriformis muscle. It may help people whose pain is coming from that specific muscle rather than the low back.
Loma Linda, CaliforniaAges 18–65 - NCT06361485RecruitingPhase 1
Umbilical cord injection for chronic low back pain
This study tests whether a special injection made from umbilical cord tissue is safe and can help with long-term low back pain. It is for adults who have not had recent back procedures or certain health problems.
Scottsdale, ArizonaAges 20 years+ - NCT05037968Recruiting
Test bone graft materials for multi-level back fusion surgery
This trial compares two bone-graft materials to help bones heal after back fusion surgery using a rod/screw system. It may help people who have ongoing back or leg pain despite at least 3 months of non-surgical treatments.
Hartford, ConnecticutAges 18 years+ - NCT07166952Recruiting
Nerve Stimulation for Chronic Sacroiliac Joint Pain
This study tests whether the SPRINT system, a device that uses mild electrical pulses to block pain signals from the sacroiliac joint, can help people with chronic pain in that area. It aims to see if this treatment works well for those who have not improved with other therapies.
Charleston, South CarolinaAges 18 years+ - NCT07579039Recruiting
Stretching and tape for pregnancy back pain
This study tests whether combining stretching exercises with special therapeutic tape can safely reduce lower back pain during pregnancy. If it works, it could offer pregnant women a non-medication option to feel better.
Rahim Yar Khan, Punjab ProvinceAges 18–35 - NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Birmingham, AlabamaAges 18 years+ - NCT07764354Recruiting
Patient education for sticking with home exercises
This study tests whether extra education helps people with chronic musculoskeletal conditions—like long-term back pain, knee arthritis, or partial rotator cuff tears—stick with their home exercise routines to feel better. If you have one of these conditions and are willing to follow a home exercise plan, this could help you manage pain.
Dammam, Eastern ProvinceAges Any age - NCT07733752Recruiting
AI symptom-checking for spine pain in physical therapy
This trial tests if a computer tool that checks your symptoms before a visit can help you and your physical therapist make better decisions about your spine care. It is for adults with neck, mid-back, or low back pain (with or without leg pain) who are starting physical therapy.
AsyutAges 18 years+
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Common questions
- Are there clinical trials for back pain?
- Yes. Clin2 currently lists 395 recruiting back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.