Clinical trials
Back Pain clinical trials
Below are recruiting back pain clinical trials, each written for real people, not researchers. We’re tracking 397 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT06715761Recruiting
Myofascial release for chronic low back pain in CrossFit athletes
This trial tests if a hands-on or tool-assisted muscle release technique can reduce long-term low back pain and improve posture in people who do CrossFit. If you have had low back pain for at least 12 weeks and do CrossFit regularly, this study may help you find relief.
Goiânia, GoiásAges 18–59 - NCT07359144Recruiting
Pilates for low back pain after childbirth
This study tests whether Pilates exercises can help relieve low back pain in women who have had a baby. It focuses on pain that started after childbirth and lasts for more than three months.
Kafr ash Shaykh, KafrelsheikhAges 20–30 - NCT07588490Recruiting
TENS for sudden severe lower back pain in the emergency room
This trial tests a pain-relief device called TENS (a small machine that sends mild electrical pulses through your skin) for people with sudden, severe lower back pain in the emergency department. Researchers want to see if TENS can help reduce your pain quickly without extra medications.
BrusselsAges 18 years+ - NCT07125027Recruiting
A mind-body program for leg pain from back issues
This trial tests a program called Move-MORE that combines movement and mindfulness to help people with long-lasting leg pain caused by a nerve problem in the lower back. It involves daily activities, weekly virtual group meetings, and tracking your progress with a wearable device.
Portland, OregonAges 18–66 - NCT06671132RecruitingPhase 2
Computer training for pain relief using smell exercises
This trial tests a computer program that uses smell training to help people with chronic low back pain. It aims to reduce pain by retraining brain connections.
Washington D.C., District of ColumbiaAges 18–85 - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Phoenix, ArizonaAges 18 years+ - NCT07133139Recruiting
Dry needling for chronic low back pain
This study tests whether a treatment called dry needling (using thin needles on muscle knots) helps people with long-term low back pain tied to muscle tightness. It is for those who have not tried this treatment before and whose main pain is in the lower back.
Pittsburgh, PennsylvaniaAges 20–70 - NCT06471920Recruiting
Telerehab for chronic low back pain in rural areas
This study tests whether a video-based physical therapy program can help people with chronic low back pain who live in rural areas. If you qualify, you'll get telerehabilitation (rehab done at home through video calls) to reduce pain and improve function.
Baltimore, MarylandAges 18 years+ - NCT06491121Recruiting
Can high-intensity training with a smartphone help chronic back pain?
This trial tests if a technology-supported high-intensity exercise program can help adults with chronic low back pain. You'll use your own smartphone to help guide the training and attend regular therapy sessions.
Wilrijk, AntwerpenAges 18–65 - NCT07633730Recruiting
Nerve Block for Back Pain in Ankylosing Spondylitis
This study tests whether a nerve-blocking injection in the back muscles can relieve persistent back pain in people with ankylosing spondylitis (a condition causing spine inflammation and stiffness). The injection targets specific nerves to reduce pain while your current disease treatment continues.
Istanbul, PendikAges 18–65 - NCT06832852Recruiting
Comparing cost-effective care for muscle and joint pain
This study compares different models of care to find the most cost-effective way to treat common muscle and joint problems (like back, neck, knee, or shoulder pain). It looks at which approach works best for patients with persistent pain to guide future treatment decisions.
Québec, QuebecAges 18–65 - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT05220202Recruiting
Program for older vets with pain and depression
This trial tests a non-medicine (non-pharmacologic) home program to help older Veterans manage musculoskeletal pain and depressive symptoms at the same time. You may be assigned to one of two approaches, and you’ll need to be able to take part from home.
Dallas, TexasAges 60–99 - NCT07111286Recruiting
Imagining movements to help chronic low back pain
This trial tests whether imagining movements (motor imagery) can help improve daily function and reduce pain in people with chronic low back pain. You will participate in a rehabilitation program, and if you are in the motor imagery group, you will also practice mentally rehearsing specific movements.
DijonAges 18 years+ - NCT05345015Recruiting
Radio waves for muscle or low back pain and function
This trial tests whether a high-frequency radio-wave treatment can reduce pain and improve movement in adults with a muscle strain (hamstring) or acute or chronic low back pain. It may help you feel less pain and function better, depending on your specific injury and medical details.
KavalaAges 18–65 - NCT06973837Recruiting
Brain study on chronic back pain and insomnia
This study looks at how the brain works in people with chronic low back pain and/or chronic insomnia. It compares these groups to healthy volunteers using MRI and pain tests.
LeuvenAges 18–60 - NCT06796881Recruiting
Comparison of two therapies for long-term low back pain
This study compares two hands-on treatments for people with chronic low back pain. One uses special tools to massage tight muscles, while the other uses gentle pressure on muscle knots. Both aim to help you move better and feel less pain.
CairoAges 25–45 - NCT05511012Recruiting
Testing movement-control assessment in low back pain
This study checks whether a therapist’s judgment about how your back controls movement matches objective measurements (more technical testing). It may help improve how low back pain rehabilitation is assessed and planned.
Brest, FinistèreAges 18–99 - NCT06282770Recruiting
Light therapy belt for lower back pain after spine surgery
This trial tests whether a special light therapy belt can help reduce long-term lower back pain you still have 1 to 5 years after spinal fusion or decompression surgery.
Los Angeles, CaliforniaAges 18–75 - NCT07467070Recruiting
Pilates for posture, core strength, and flexibility in young adults with low back pain
This study tests whether a 6-week Pilates program can improve posture, core strength, and flexibility in young adults with mild to moderate low back pain that has no clear cause. It could help you learn exercises to ease your pain and strengthen your back.
Lahore, Punjab ProvinceAges 18–25 - NCT06785363Enrolling by invitation
Pelvic ligament release for postpartum back pain
This study tests a technique to release a tight pelvic ligament that can cause lower back pain after pregnancy. It may help women who recently gave birth and have mechanical back or pelvic pain.
CairoAges 25–30 - NCT06288282Recruiting
Predicting pain and opioid misuse in chronic back pain
This study looks at how thinking and behavior affect long-term pain and opioid use in people with chronic lower back pain. It aims to find better ways to manage pain and prevent medication misuse.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for back pain?
- Yes. Clin2 currently lists 397 recruiting back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.