Clinical trials
Biologics clinical trials
Below are recruiting biologics clinical trials, each written for real people, not researchers. We’re tracking 636 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06450080Recruiting
Tongue Cancer Imaging and Lab Study
This study looks at how tongue cancer appears on scans and in lab tests before any treatment. The goal is to better understand the disease and possibly find new ways to track it.
AmiensAges 18 years+ - NCT06451497RecruitingPhase 1
Testing ZM008 alone and with toripalimab for advanced cancers
This trial tests a new drug called ZM008, which targets a protein on some cancer cells, first alone and then combined with another drug, toripalimab, for people with advanced solid tumors that have stopped responding to standard treatments.
Boston, MassachusettsAges 18 years+ - NCT06464159Recruiting
A new treatment for preeclampsia during pregnancy
This study is testing a new treatment strategy for women with preeclampsia, a serious pregnancy condition that causes high blood pressure. If you have preeclampsia or a normal pregnancy, you may be able to join to help find better treatments.
ParisAges 18–50 - NCT06471387Recruiting
Study of genes linked to nicotine addiction
This study looks at your genes to understand why some people get addicted to nicotine. Your participation could help develop new treatments for quitting smoking.
NicosiaAges 18–60 - NCT06477653RecruitingPhase 2
Dupilumab for hypereosinophilic syndrome with ongoing symptoms
This trial tests if dupilumab, added to your current treatment, can help with remaining symptoms of hypereosinophilic syndrome (HES) like asthma, eczema, nasal polyps, or eosinophilic esophagitis. You may qualify if you're already on a biologic therapy that lowers eosinophils but still have bothersome symptoms.
Bethesda, MarylandAges 18–99 - NCT05421455Recruiting
Early vs delayed surgery for Crohn’s bowel narrowing
This study compares two timing choices for surgery in people with Crohn’s disease who have bowel narrowing (strictures) causing blockage symptoms. The goal is to see whether operating earlier leads to better control of symptoms and inflammation when other treatments haven’t worked.
Nanjing, JiangsuAges 18–60 - NCT07187817Recruiting
Sequential biologic treatments for psoriasis
This trial looks at how different biologic treatments work when used one after another for people with plaque psoriasis. It may help find the best order of treatments to keep your skin clear.
Bath, SomersetAges 18 years+ - NCT06487624RecruitingPhase 1
Study of HCB301 for advanced solid tumors and Hodgkin lymphoma
This trial tests a new drug called HCB301, which targets proteins that help cancer hide from the immune system. It is for people with advanced solid tumors or classical Hodgkin lymphoma who have tried other treatments without success.
Greenville, South CarolinaAges 18 years+ - NCT06490029Recruiting
Hearing loss from cancer treatment: a diagnosis study
This study looks at hearing problems caused by cancer treatments that can damage the ears or nervous system. It aims to better understand and diagnose these side effects to help patients.
ParisAges 18 years+ - NCT06490887Recruiting
Spine unit modeling with high-throughput analysis (SUIT)
This study looks at cells from people with degenerated discs or from donated fat or placenta tissue. It aims to understand how these cells work and might help develop new treatments for back pain.
Milan, MIAges 18–60 - NCT06502873Recruiting
Study of colon samples in IBD and healthy people
This study is gathering information from people with active Crohn's disease or ulcerative colitis, and from people without IBD. Researchers will look at samples from the colon to learn more about these conditions.
LiègeAges 18 years+ - NCT06516562Recruiting
Heart failure study in Vietnam: following patients' health over time
This study follows people with heart failure in Vietnam to understand their health and treatment over time. It does not test a new drug—just collects information to improve care.
Ho Chi Minh CityAges 18 years+ - NCT06529913Recruiting
Metals, pollutants, and risk of allergies
This study looks at whether heavy metals, nanoparticles, and other pollutants in the environment increase the risk of allergic diseases like contact dermatitis. If you have a metal allergy or are a healthy adult, you may help researchers understand how these exposures affect your health.
BolognaAges 18 years+ - NCT06530303RecruitingPhase 1/Phase 2
Personalized immune cell therapy for colorectal cancer
This trial tests a treatment made from your own immune cells (called TILs) that are taken from your tumor, grown in a lab, and given back to you along with immunotherapy. It is for people with advanced colon or rectum cancer who have run out of standard options.
Beijing, Beijing MunicipalityAges 16–90 - NCT06544863Recruiting
Better support for cirrhosis and liver transplant patients
This study tests a new care support program for people with cirrhosis or who have had a liver transplant. It aims to improve how patients are followed and helped at the hospital.
ParisAges 18 years+ - NCT06549478RecruitingPhase 1
Radiation therapy guided by PET scan for painful bone cancer spread
This trial uses a special PET scan to guide radiation therapy for painful spots where cancer has spread to the bone. The goal is to treat the pain more precisely and see if this image-guided approach works well.
Duarte, CaliforniaAges 18 years+ - NCT06551155Recruiting
Blood test to screen bone health and fracture risk
This study uses a simple blood test to look for early signs of bone loss and fracture risk. It's for people 40 and older who are either healthy, have early bone thinning, or have known osteoporosis.
BolognaAges 40 years+ - NCT06560502Recruiting
Testing new treatments for diabetic foot and leg ulcers
This trial tests whether adding a special treatment (cellular acellular and matrix-like products) to standard wound care helps diabetic foot ulcers and venous leg ulcers heal faster. It may be an option if you have a diabetes-related foot ulcer that hasn't healed with standard care.
Circleville, OhioAges 21 years+ - NCT06562413Recruiting
Finding New Biological Clues in Hard-to-Treat Migraine
This study looks for new biological markers in people whose migraines don't respond to standard treatments. It aims to better understand why some migraines are hard to treat and may help guide future therapies.
PaviaAges 18–75 - NCT06564831Recruiting
Placental graft for diabetic foot ulcers
This study tests whether a special placental tissue graft placed on a diabetic foot ulcer helps it heal faster than standard wound care alone. It is for people with a diabetic foot ulcer that has not healed after 4 weeks of usual care.
Clinton Township, MichiganAges 18 years+ - NCT06576622Recruiting
Periodontal disease, bacteria, and miscarriage
This study looks at whether gum disease and oral bacteria are linked to repeated pregnancy loss. If you have had multiple miscarriages, your gum health may play a role.
ToulouseAges Up to 18 years - NCT06595966Recruiting
Blood test study for early detection of breast cancer return
This study looks for tiny bits of cancer DNA in your blood after breast cancer surgery. A blood test called NGS may help doctors find early signs of cancer coming back, and you would give samples and have checkups for 3 years.
Hangzhou, ZhejiangAges 18 years+ - NCT04509050Recruiting
Testing a highly effective CF medicine in young children
This study looks at how well a highly effective cystic fibrosis (CF) medicine works in infants and young children, and what biological changes it causes. It may help families understand whether the medicine improves CF function and related measures early in life.
Birmingham, AlabamaAges Up to 10 years - NCT06604728Recruiting
IV vs. shot biologics for IBD: which works better?
This study compares intravenous (IV) and under-the-skin (subcutaneous) biologic drugs for people with Crohn's disease or ulcerative colitis. It helps doctors understand if switching from the IV form to a shot is as effective and well-tolerated.
RomaAges 18 years+
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Common questions
- Are there clinical trials for biologics?
- Yes. Clin2 currently lists 636 recruiting biologics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biologics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biologics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.