Clinical trials
Biologics clinical trials
Below are recruiting biologics clinical trials, each written for real people, not researchers. We’re tracking 637 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06613009RecruitingPhase 1
New Drug IBI3009 for Advanced Small Cell Lung Cancer
This trial tests a new drug called IBI3009 for people with advanced small cell lung cancer that cannot be removed by surgery. It aims to see how safe the drug is and how well it works against the cancer.
Westmead, New South WalesAges 18–75 - NCT06630065Recruiting
Ketamine study for depression using brain scans
This trial uses brain scans to understand how ketamine affects negative emotions in people with depression. It may help explain why ketamine works and who benefits most.
Paris, ParisAges 18 years+ - NCT06663839RecruitingPhase 1
Study of NILK-2301 for advanced colorectal cancer
This trial tests a new drug called NILK-2301 for people with colorectal cancer that has spread or cannot be removed. It is for those who have already tried at least one other treatment and have relatively small tumors.
BarcelonaAges 18 years+ - NCT06666660Recruiting
Multivitamin study for middle-aged adults
This trial tests whether taking a daily multivitamin and mineral supplement can slow or reverse biological aging in healthy middle-aged adults. It involves blood tests, wearing an OURA ring, and using a study app.
Singapore, SingaporeAges 40–60 - NCT06669702Recruiting
Exercise therapy for axial spondyloarthritis on biologics
This study tests whether a supervised exercise program can help people with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine) who are already on biologic medications. It aims to see if exercise reduces inflammation and improves symptoms.
Loughborough, LeicestershireAges 18 years+ - NCT06700070RecruitingEarly Phase 1
Testing a microdose drug in solid tumors before surgery
This study tests a tiny amount of an experimental drug (PBA-0111) injected directly into tumors that will be surgically removed later. The goal is to see how the drug affects the tumor tissue, which may help guide future treatments for solid tumors like head and neck cancer, certain sarcomas, or triple-negative breast cancer.
Shreveport, LouisianaAges 18 years+ - NCT06703034Recruiting
Studying the immune response in people who had severe or mild COVID-19
This study looks at how the body's immune system reacted to COVID-19 in people who had either severe or mild cases. The goal is to learn more about a specific part of the immune response (called IFN-I) to better understand the disease.
LyonAges 18 years+ - NCT07414745RecruitingPhase 3
Study of a bone graft for two-level lower back fusion
This trial tests a special material (rhBMP-2) placed inside a cage to help two nearby vertebrae in the lower back fuse together. It is for patients whose disc problems or deformity have not improved after at least 3 months of other treatments, and who have significant pain and limited function.
Kobe, HyōgoAges 18–80 - NCT07296107Recruiting
IVF and pregnancy study at Columbia
This study looks at how IVF pregnancies affect mothers and babies, separate from genetic factors. If you are pregnant at 18-28 weeks and receiving care at Columbia University Medical Center, you and your baby may be eligible.
New York, New YorkAges 18–50 - NCT06713889Recruiting
Study of heart valve disease and events
This study looks for biological markers in the blood that might help predict heart-related events in people with a narrowed aortic heart valve. It aims to improve care for those with this condition, whether or not they have a procedure called TAVI to replace the valve.
LyonAges 18 years+ - NCT06715267Recruiting
MPN in youth: studying disease features and complications
This study looks at young people (children, teens, and adults under 30) who have a type of blood cancer called myeloproliferative neoplasm (MPN). It aims to better understand the disease and its complications over time, with the goal of improving care.
BrestAges birth–30 years - NCT06718569Recruiting
Pain in Inflammatory Joint Diseases
This study looks at pain in people with inflammatory joint diseases. It aims to understand how pain changes when you start or switch to a newer type of arthritis medication.
OsloAges 18 years+ - NCT06718894Recruiting
New treatment strategy for primary podocytopathies
This trial is testing a new treatment approach for people with certain kidney diseases called podocytopathies (like FSGS and MCD). It may help if you have active disease, even after a kidney transplant, or if you have another type of kidney inflammation.
MilanAges Any age - NCT06724536Recruiting
Study of gut bacteria and TKIs in chronic myeloid leukemia
This trial looks at how gut bacteria affect the way chronic myeloid leukemia (CML) patients respond to tyrosine kinase inhibitor (TKI) medications. It may help doctors understand why some people have better outcomes than others.
TorinoAges 18 years+ - NCT06727500Recruiting
Exercise training for kids with obesity
This trial tests whether two types of exercise training (high-intensity interval training or a mix of HIIT and jumping exercises) improve muscle and tendon health in children and teenagers with obesity. It looks at how results differ based on whether kids are before or after their growth spurt.
SantiagoAges 7–17 - NCT06727773RecruitingPhase 2
Memantine and exercise to protect thinking during chemo for breast cancer
This study tests whether a medicine called memantine combined with a structured exercise program can help protect your thinking and memory during chemotherapy for breast cancer. It may also help understand how these treatments work in the body.
Chapel Hill, North CarolinaAges 18 years+ - NCT06735170RecruitingPhase 1/Phase 2
Tuberoplasty vs. balloon spacer for irreparable rotator cuff tears
This trial tests two treatments for large, irreparable rotator cuff tears that cause pain: a surgical procedure called tuberoplasty (shaping the bone) versus placing a small balloon spacer under the shoulder bone. The goal is to see which offers better pain relief in people who have already had unsuccessful shoulder surgery and are 65 or older.
Minneapolis, MinnesotaAges 65 years+ - NCT06757504RecruitingPhase 2
Testing TTYP01 tablets for autism in kids and teens
This study tests an investigational tablet (TTYP01) to see if it can help adolescents and children with autism spectrum disorder (ASD). The goal is to find out if the drug improves symptoms and is safe for this age group.
BeijingAges 6–16 - NCT06767501Recruiting
Amnion graft for diabetic foot ulcers vs. standard care
This trial tests whether a special amnion membrane graft can help heal diabetic foot ulcers better than standard care alone. If you have a diabetic foot ulcer that hasn't healed after standard treatment, this study may offer a new option.
Roanoke, VirginiaAges 18 years+ - NCT06770621Recruiting
Glucagon response study in new type 1 diabetes
This study looks at how the body makes glucagon (a hormone that raises blood sugar) in children and teens with new type 1 diabetes. It aims to understand why some people may have dangerous low blood sugars, so doctors can better prevent them in the future.
Brussels, Woluwe-saint-lambertAges 2–30 - NCT06771479RecruitingPhase 1
Monkeypox vaccine safety and immune response study
This trial tests a new monkeypox vaccine to see if it is safe and helps the body build protection. It may be an option for adults who were born before 1980 and received a smallpox vaccine, or who meet other health criteria.
Zhengzhou, HenanAges 18 years+ - NCT06778447Recruiting
Disc injection for chronic low back pain
This study tests whether injecting a special disc material (nucleus pulposus allograft) into the damaged discs of your lower back can safely reduce pain and improve function. It's for people with long-term, moderate to severe low back pain from disc disease that hasn't gotten better with other treatments.
Napa, CaliforniaAges 22–85 - NCT06778746Recruiting
Study of Biologics for Severe Asthma in Hong Kong
This study looks at how biologic medicines (special injections or infusions) are used to treat severe asthma in Hong Kong. It may help researchers understand why some people stop or switch these treatments.
Hong KongAges 18 years+ - NCT06780241Recruiting
Sex differences in valvular heart disease
This study uses special MRI scans to look at how valvular heart disease (like leaky or narrowed aortic valves) affects men and women differently. It aims to find unique biological patterns that could lead to better treatments.
Cleveland, OhioAges 18–90
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Common questions
- Are there clinical trials for biologics?
- Yes. Clin2 currently lists 637 recruiting biologics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biologics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biologics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.