Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03202303RecruitingPhase 2
CBDV treatment study for children with autism irritability
This Phase 2 study tests CBDV, a form of cannabis-based medicine, compared with placebo (dummy medicine) in children with autism who have significant irritability and social challenges. It aims to see whether CBDV can improve behavior and overall symptom severity safely over the study period.
New York, New YorkAges 5–18 - NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT06102941Recruiting
Cognitive training for OCD in kids aged 8 to 12
This study tests a cognitive training program to help young children with OCD. It's designed for kids whose OCD is their main problem and who are not currently on medication or in other therapy.
New York, New YorkAges 8–12 - NCT06093906Recruiting
Positive processes and transition to health (PATH) study
This study tests a new therapy that may help people recover after a stressful life event. Over about 6 weeks, you'll work with a coach to retrain your brain's patterns and feel more in control again, as well as reconnect with positive activities.
Newark, DelawareAges 18–65 - NCT06096740Recruiting
Talking therapy for PTSD and its effects on the brain
This study looks at how a specific type of talk therapy affects the way your brain processes rewards. You'd join a group that either starts therapy right away or waits a bit before starting. Your brain activity will be scanned with an MRI to see changes.
Austin, TexasAges 18–65 - NCT04558541Recruiting
Speech and grammar training study for kids with language disorder
This study looks at how children with developmental language disorder understand and produce parts of speech, especially verb endings and grammar patterns. It may help researchers develop better ways to support communication in kids who struggle with language.
Tucson, ArizonaAges 4–8 - NCT06058377RecruitingPhase 3
Adding immunotherapy to chemo for stage II-III breast cancer
This trial tests whether adding the immunotherapy drug durvalumab to standard chemotherapy works better than chemo alone for people with hormone receptor positive, HER2 negative breast cancer that is stage II or III and has a high-risk genetic score (MammaPrint High Risk 2).
Birmingham, AlabamaAges 18 years+ - NCT06072898RecruitingPhase 2
Psilocybin brain imaging trial for depression
This study tests whether a single dose of psilocybin (a psychedelic compound) can help treat depression by looking at brain changes on MRI. It is designed for people with moderate-to-severe depression who have not responded well to other treatments.
Toronto, OntarioAges 18–64 - NCT06066983Recruiting
Treating anxiety in children with autism (DINO RCT)
This study tests a therapy to help young children with autism who also have anxiety. The goal is to reduce anxious behaviors and improve daily life.
Baltimore, MarylandAges 4–6 - NCT06067737RecruitingPhase 2
Psilocybin and buprenorphine for opioid use disorder
This study tests whether adding psilocybin (a psychedelic medicine) to buprenorphine (a medication for opioid use disorder) can help people stop using opioids and stay in recovery. It is for people who have already been on buprenorphine but are still using other opioids.
Baltimore, MarylandAges 21–70 - NCT06078709RecruitingPhase 2
Pre-surgery radiation and chemo for esophageal cancer
This trial tests a shorter course of radiation combined with chemotherapy (FOLFOX) before surgery for esophageal or stomach-junction cancer. It aims to reduce side effects and still improve outcomes.
Scottsdale, ArizonaAges 18 years+ - NCT05986552Enrolling by invitation
How group or individual therapy affects schema therapy for BPD
This study compares individual and group formats of schema therapy for borderline personality disorder (BPD). It aims to see which format works better for reducing symptoms and improving daily life.
AmsterdamAges 18–70 - NCT05999240RecruitingPhase 2
Pimavanserin for rigid-compulsive symptoms in autism
This trial tests if the drug pimavanserin can help reduce rigid or repetitive behaviors in people with autism spectrum disorder. It may be an option if you or your child struggle with these symptoms and want to try a new treatment.
Lawrence, KansasAges 12–40 - NCT05963568RecruitingPhase 3
Prevent more strokes with a daily anti-clotting heart pill
This Phase 3 trial tests whether a daily “polypill” can reduce the chance of another stroke after a recent ischemic stroke. It may help people by improving several heart-and-blood-vessel risks at once, but only if it fits safely with their medical situation.
ParakouAges 18–100 - NCT05950581Recruiting
Twin-block braces with clear plates for jaw misalignment
This study tests a removable orthodontic device (twin-block with clear plates) to improve how the upper and lower jaws fit together in children. It may help if you have a specific “Class II” jaw pattern caused mainly by a lower jaw that sits back.
HamaAges 10–13 - NCT05913752RecruitingPhase 1/Phase 2
Test drug CMND-100 in people with alcohol use disorder
This early study tests the safety and dosing of CMND-100 in first-time participants, including people with alcohol use disorder (AUD) and some healthy volunteers. It may help researchers understand whether the drug is safe, and how it might affect alcohol use in AUD.
New Haven, ConnecticutAges 18–60 - NCT05934487Recruiting
Monitoring device trial for stable heart failure symptoms
This trial tests whether a wearable home monitoring system (myCordella™) can help people with moderate heart failure (NYHA class II or III) by tracking heart pressure and supporting follow-up care. It may help detect changes earlier so clinicians can adjust treatment sooner.
Phoenix, ArizonaAges 18 years+ - NCT05913947RecruitingPhase 4
Lithium or cariprazine for bipolar depression
This trial compares lithium versus cariprazine to treat an episode of depression in people with bipolar disorder. It may help find which medicine works better and is safer during the acute (active) phase of depression.
AalborgAges 18–65 - NCT05889624Recruiting
Study of treatments for childhood migraine headaches
This study looks at ways to help children and teens with migraine headaches by testing a care approach that includes access to evidence-based treatment. It may help if your child has frequent migraine headaches and is starting (or not already on) certain migraine-preventive medicines.
Birmingham, AlabamaAges 10–17 - NCT05884853Recruiting
Social brain training for adults with autism
This study tests a brain training program for adults with autism to see if it improves social skills. It may help participants understand social situations better.
Taipei, Zhongzheng Dist.Ages 18–50 - NCT05861752Recruiting
Study of sexual risk behaviors and mental health patterns
This case-control study looks at people with specific sexual behavior-related conditions (like certain paraphilias, compulsive sexual behavior, or sex during sleep) to understand factors linked with risk for sexual violence. The goal is to learn what patterns may be involved so better help and prevention strategies can be developed.
Stockholm, Stockholm CountyAges 18 years+ - NCT05850689RecruitingPhase 3
Lumateperone add-on for major depression that didn’t improve
This study tests whether adding lumateperone to an antidepressant helps adults with major depressive disorder (MDD) who haven’t improved enough after trying at least two different antidepressants. It may help reduce depressive symptoms more than antidepressants alone.
Huntsville, AlabamaAges 18–65 - NCT05857813Recruiting
Social skills group training for teens with autism
This trial tests a structured social skills training group for adolescents with autism spectrum disorder (ASD) to improve day-to-day social functioning. It involves both the teen and a Chinese-speaking caregiver who helps support the training at home.
TaipeiAges 11–20 - NCT05859347Recruiting
Brain stimulation study for cannabis use disorder
This trial tests whether a treatment called repetitive transcranial magnetic stimulation (a non-surgical magnetic stimulation to the brain) can help people reduce or stop cannabis use. You may be eligible if you have cannabis use disorder and meet specific safety and symptom criteria.
Toronto, OntarioAges 18–65
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,350 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.