Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,363 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07556692Recruiting
Home Brain Stimulation for Bipolar Depression
This study tests whether a device you use at home can help reduce depression symptoms in people with bipolar disorder. The device uses gentle electrical stimulation on the scalp to potentially improve mood.
LondonAges 18 years+ - NCT07619092Recruiting
Flumazenil to reverse sedation during depression treatment
This trial tests whether flumazenil (a medication that reverses sedation from anti-anxiety drugs) can safely help patients wake up faster after electroconvulsive therapy (ECT), a treatment for severe depression. The goal is to see if it improves recovery time without causing problems.
Frederiksberg, Capital RegionAges 18 years+ - NCT06880796Enrolling by invitation
Mindfulness therapy for serious mental illness
This trial tests whether mindfulness-based therapy helps people with serious mental illnesses like schizophrenia or mood disorders. You'll learn mindfulness skills in a group setting at your community mental health center.
Providence, Rhode IslandAges 18 years+ - NCT06558201Enrolling by invitation
Open-label extension for completers of earlier study
This trial is for people who finished a 12-week study (NCT06221852) and still meet its original requirements. It offers continued access to the study treatment.
Belmont, MassachusettsAges 18–45 - NCT07359157Recruiting
Support program for WRCH patients with legal history
This study offers a group program at Worcester Recovery Center and Hospital (WRCH) aimed at helping people who have been involved with the legal system. It is designed for current patients at WRCH who are at least 18 years old and comfortable speaking English.
Worcester, MassachusettsAges 18 years+ - NCT07639853Enrolling by invitation
Doctor feedback survey on Concerto Versa coils
This study gathers feedback from doctors who use Concerto Versa detachable coils (small metal devices that help treat brain aneurysms). The survey helps improve how these coils work and are used.
El Paso, TexasAges 22 years+ - NCT05878730Recruiting
Melatonin study for people stable on long-term lithium
This trial tests whether taking melatonin (a sleep-related hormone) changes how your body responds to lithium in people with bipolar disorder who are currently stable. It may help researchers understand lithium’s effects and how sleep/circadian timing could matter.
Paris, Île-de-France RegionAges 18–70 - NCT07494305RecruitingPhase 2
Testing a new drug for bipolar depression
This trial tests an investigational drug called LB-102 for people with bipolar I disorder who are currently experiencing a major depressive episode without psychosis. It aims to see if the drug is safe and effective for treating depression symptoms.
Bentonville, ArkansasAges 18–65 - NCT07105865Recruiting
Nickel and LTPs in stomach and bowel issues
This study looks at whether being sensitive to nickel or certain proteins called LTPs is linked to ongoing stomach and bowel problems. It aims to find better ways to diagnose and help people with functional dyspepsia or irritable bowel syndrome.
NaplesAges 4–65 - NCT07411222Recruiting
Emotional Eating, Sleep, and Metabolic Health Study
This study examines how emotional eating, sleep quality, and mental state relate to metabolic syndrome (a group of conditions like high blood pressure, high blood sugar, and extra belly fat) in people with stable schizophrenia or bipolar disorder. It aims to help understand and improve overall health.
Bolu, BoluAges 18–65 - NCT03333200Recruiting
Study of genetic brain diseases over time
This trial follows people with genetic neurodegenerative (brain-wasting) disorders over time to better understand how the condition changes. The goal is to learn patterns that could help future treatments or care plans.
Pittsburgh, PennsylvaniaAges Any age - NCT04057378RecruitingPhase 4
Testing the best electrical settings for ECT for depression
This trial studies which electrical “pulse settings” work best during electroconvulsive therapy (ECT) for people with depression. It may help doctors personalize ECT so the treatment is safer and works as well as possible for you.
ÖrebroAges 18 years+ - NCT04532047RecruitingPhase 1
Fetal enzyme therapy trial for certain inherited storage disorders
This Phase 1 trial tests an enzyme replacement treatment given to a developing baby before birth for specific inherited “lysosomal storage” diseases. The goal is to see if the treatment is safe and can improve outcomes for babies diagnosed in pregnancy.
San Francisco, CaliforniaAges 18–50 - NCT04946916Recruiting
Testing blood/brain marker levels and thinking problems in psychiatric illness
This study looks at neurofilament light (a brain/nerve injury marker) and how it relates to thinking and memory problems in people with certain psychiatric conditions. It may help researchers understand brain changes and cognitive impairment, which could guide better diagnosis in the future.
BronAges 45–80 - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT05157620Recruiting
Yoga and exercise program for veterans with severe mental illness
This trial tests an exercise and yoga-style wellness program to help veterans with severe mental health conditions feel and function better. It may help with symptoms and overall well-being, especially if your condition is currently stable.
Pittsburgh, PennsylvaniaAges 18–70 - NCT05178966Recruiting
One-day therapy education to lessen bipolar caregiver stress
This study tests whether a one-day session that teaches patients and caregivers about bipolar disorder can reduce the caregiver’s burden (stress and workload). You may be eligible if you’re an adult with bipolar disorder and have a regular caregiver willing to join the session.
MontpellierAges 18 years+ - NCT05408715Recruiting
Natural history study of growth in children with type II collagen disorders
This study follows children with certain inherited “type II collagen” conditions that cause short height, to better understand how growth changes over time. It does not test a new treatment; it mainly tracks health and growth so doctors can learn what to expect.
ParisAges Up to 12 years - NCT05555875Recruiting
Study how people engage with digital mental health tools
This study looks at what helps (or prevents) people from using digital mental health programs. You may join if you have meaningful depression and/or anxiety symptoms and you can use a smartphone for the study apps.
Boston, MassachusettsAges 18–75 - NCT05648591RecruitingPhase 4
Iloperidone study for teens with schizophrenia or bipolar I
This Phase 4 study checks how safe and well-tolerated iloperidone is when used in a typical, open-label way for teenagers. It may help doctors better understand side effects and safety in teens with schizophrenia or bipolar I disorder.
Little Rock, ArkansasAges 12–17 - NCT05958940Recruiting
Bright light therapy study for depression
This trial studies whether daily bright light therapy can reduce depressive symptoms. It’s for adults with depression (including some with bipolar depression), and you would fill out questionnaires and be screened for safety.
EindhovenAges 18–65 - NCT06188754Recruiting
Healthy lifestyle program for bipolar disorder and sleep issues
This study tests a healthy lifestyle program (including diet changes) for people with bipolar disorder who have sleep problems. It aims to improve sleep and overall well-being by teaching new habits.
Berkeley, CaliforniaAges 18–65 - NCT06236932Recruiting
Infection risk in obesity study
This study looks at how obesity and related conditions affect your body's ability to fight infections. It may help find ways to prevent illness in people with obesity.
NaplesAges 18–65 - NCT06337188Recruiting
Adaptive communication device for severe motor impairments
This study tests a new wearable communication device that you can control with your head, hand, or foot. It may help people who have trouble speaking or typing due to conditions like spinal cord injury, stroke, or cerebral palsy.
Omaha, NebraskaAges 6 years+
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,363 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.