Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07026461RecruitingPhase 4
TMS for depression: comparing two brain stimulation methods
This trial compares two types of transcranial magnetic stimulation (TMS) to see which works better for people with depression. TMS uses magnetic pulses to stimulate brain areas involved in mood regulation.
ÖrebroAges 18 years+ - NCT04057378RecruitingPhase 4
Testing the best electrical settings for ECT for depression
This trial studies which electrical “pulse settings” work best during electroconvulsive therapy (ECT) for people with depression. It may help doctors personalize ECT so the treatment is safer and works as well as possible for you.
ÖrebroAges 18 years+ - NCT06853873Enrolling by invitation
Alcohol counseling for safer pregnancies
This trial tests a counseling program to help pregnant women reduce risky alcohol use. The program is designed to support women in making healthier choices for themselves and their baby.
Cape TownAges 18 years+ - NCT04946916Recruiting
Testing blood/brain marker levels and thinking problems in psychiatric illness
This study looks at neurofilament light (a brain/nerve injury marker) and how it relates to thinking and memory problems in people with certain psychiatric conditions. It may help researchers understand brain changes and cognitive impairment, which could guide better diagnosis in the future.
BronAges 45–80 - NCT06236932Recruiting
Infection risk in obesity study
This study looks at how obesity and related conditions affect your body's ability to fight infections. It may help find ways to prevent illness in people with obesity.
NaplesAges 18–65 - NCT06342440Recruiting
Early detection of colon cancer and advanced polyps
This study aims to find colorectal cancer and advanced polyps (adenomas) earlier by looking at blood samples. Researchers hope a simple blood test might one day help detect colon cancer before it spreads.
Monrovia, CaliforniaAges 18 years+ - NCT06338280RecruitingPhase 2
Observing methadone treatment remotely
This study tests if using a smartphone app to watch you take your methadone works as well as going to a clinic every day. It might make treatment easier for you.
Chicago, IllinoisAges 18–64 - NCT06337188Recruiting
Adaptive communication device for severe motor impairments
This study tests a new wearable communication device that you can control with your head, hand, or foot. It may help people who have trouble speaking or typing due to conditions like spinal cord injury, stroke, or cerebral palsy.
Omaha, NebraskaAges 6 years+ - NCT06188754Recruiting
Healthy lifestyle program for bipolar disorder and sleep issues
This study tests a healthy lifestyle program (including diet changes) for people with bipolar disorder who have sleep problems. It aims to improve sleep and overall well-being by teaching new habits.
Berkeley, CaliforniaAges 18–65 - NCT05878730Recruiting
Melatonin study for people stable on long-term lithium
This trial tests whether taking melatonin (a sleep-related hormone) changes how your body responds to lithium in people with bipolar disorder who are currently stable. It may help researchers understand lithium’s effects and how sleep/circadian timing could matter.
Paris, Île-de-France RegionAges 18–70 - NCT05703412Enrolling by invitation
Text or app check-ins after discharge for serious mental illness
This study tests an mHealth (phone-based) program that helps people with serious mental illness after leaving the hospital. It may help you stay connected to care and support in the community after discharge.
Providence, Rhode IslandAges 18 years+ - NCT05648591RecruitingPhase 4
Iloperidone study for teens with schizophrenia or bipolar I
This Phase 4 study checks how safe and well-tolerated iloperidone is when used in a typical, open-label way for teenagers. It may help doctors better understand side effects and safety in teens with schizophrenia or bipolar I disorder.
Dothan, AlabamaAges 12–17 - NCT05368038Enrolling by invitation
Newborn screening program for babies up to 4 weeks old
This trial tests a flexible newborn screening process that looks for certain conditions early in life. It may help by catching problems sooner, when treatment can be started earlier.
Brooklyn, New YorkAges Up to 4 weeks - NCT05157620Recruiting
Yoga and exercise program for veterans with severe mental illness
This trial tests an exercise and yoga-style wellness program to help veterans with severe mental health conditions feel and function better. It may help with symptoms and overall well-being, especially if your condition is currently stable.
Pittsburgh, PennsylvaniaAges 18–70 - NCT04987229Enrolling by invitationPhase 3
Kid’s long-term safety follow-up for OLZ and SAM treatment
This study checks how safe a kid’s ongoing treatment is over a longer period. It is mainly for children who already finished a related study and may benefit from continuing the same medicines.
Dothan, AlabamaAges 10–17 - NCT04532047RecruitingPhase 1
Fetal enzyme therapy trial for certain inherited storage disorders
This Phase 1 trial tests an enzyme replacement treatment given to a developing baby before birth for specific inherited “lysosomal storage” diseases. The goal is to see if the treatment is safe and can improve outcomes for babies diagnosed in pregnancy.
San Francisco, CaliforniaAges 18–50 - NCT04462978Recruiting
Food allergies in children
This study looks at a type of food allergy that is not caused by Immunoglobulin E (IgE), a protein involved in many allergic reactions. The goal is to better understand these non-IgE food allergies in children and how they affect them.
NaplesAges 1 day–14 years - NCT03333200Recruiting
Study of genetic brain diseases over time
This trial follows people with genetic neurodegenerative (brain-wasting) disorders over time to better understand how the condition changes. The goal is to learn patterns that could help future treatments or care plans.
Pittsburgh, PennsylvaniaAges Any age - NCT02878408Recruiting
Study of immune and genetics factors in bipolar or schizophrenia
This study looks at how the immune system, genetics, inflammation, and past exposures may relate to bipolar disorder or schizophrenia. It may help researchers understand the cause and find better ways to support people with these conditions.
Créteil, FranceAges 16 years+ - NCT02560805RecruitingPhase 2
Study drugs that affect stress nerves and blood pressure in PTSD
This Phase 2 study looks at how stress-related nerve activity and a hormone called angiotensin II may be involved in PTSD, and how specific blood-pressure-related medicines affect the body. You may be eligible if you are a PTSD patient (or a matched control without PTSD) and meet safety criteria.
Decatur, GeorgiaAges 18–65 - NCT05334069Recruiting
Blood test study for early cancer detection in patients
This study collects blood from people with cancer and people without cancer (or with possible cancer) to test whether new blood tests can detect cancer earlier. Your blood samples help researchers evaluate how well these tests work.
Anchorage, AlaskaAges 40–75 - NCT07458100Recruiting
Step-by-step digital therapy for emotional disorders
This trial tests a digital stepped-care program for people with emotional disorders like depression, anxiety, OCD, PTSD, or eating disorders. It uses online tools to help manage symptoms, and you may access different levels of support based on your needs.
BeijingAges 18–65 - NCT06532279RecruitingPhase 2
Testing BMX-001 with chemoradiation for head and neck cancer
This trial tests whether adding BMX-001 (a drug that may protect healthy tissues) to standard chemoradiation can reduce side effects and improve outcomes for people with head and neck cancer. It's a randomized study, so you would have a 50/50 chance of getting BMX-001 or a placebo.
Gilbert, ArizonaAges 18 years+ - NCT05712057Recruiting
Brain stimulation vs therapy for emotion regulation problems
This trial compares a type of brain stimulation (rTMS) to therapy to help people better manage strong emotions. You may be eligible if you have ongoing difficulties with emotion control and meet specific mood, anxiety, or related symptom criteria.
Durham, North CarolinaAges 18–55
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,350 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.