Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05081024Recruiting
Blood test biomarker to help preserve organs in rectal cancer
This study looks at a blood test (ctDNA, a way to detect cancer DNA in the bloodstream) to help doctors choose treatment that may spare organs for people with stage II–III rectal cancer. You may be followed to see how well the blood test can guide treatment decisions.
Portland, OregonAges 18 years+ - NCT05023018RecruitingPhase 2
NEO100 for recurrent or progressive high-grade meningioma
This trial studies NEO100, a treatment for adults and children (age 12+) with Grade II or III meningioma that has come back or kept growing after surgery and radiation. It may help shrink tumors or slow growth when standard options have not worked well enough.
Los Angeles, CaliforniaAges 12 years+ - NCT05053971RecruitingPhase 1/Phase 2
Entinostat plus ZEN003694 for advanced solid tumors
This Phase 1/2 study tests a new combination anti-cancer treatment (entinostat plus ZEN003694) in people with advanced solid tumors that can’t be controlled with standard care. It aims to find a safe dose and see whether the treatment can shrink tumors or control the disease.
New Haven, ConnecticutAges 18 years+ - NCT05027945RecruitingPhase 2
Stem cell transplant for people with VEXAS syndrome
This Phase 2 trial tests whether an allogeneic stem cell transplant (from a donor) can treat VEXAS syndrome. It may help calm the body’s overactive inflammation and improve symptoms in eligible adults.
Bethesda, MarylandAges 18–75 - NCT05064280RecruitingPhase 2
Pembrolizumab plus lenvatinib for brain metastases from solid tumors
This Phase 2 trial studies whether combining pembrolizumab with lenvatinib can shrink or control brain metastases in people with triple-negative breast cancer, lung cancer, or other solid tumors. It focuses on patients who have measurable brain lesions that can be followed on MRI.
Houston, TexasAges 18 years+ - NCT05017311RecruitingPhase 4
Testing a depression medication plan using symptom predictions
This Phase 4 study tests an “optimized” medication approach for adults with major depressive disorder (unipolar depression) based on how you respond over time. It may help your care team choose treatments more effectively and reduce trial-and-error.
Calgary, AlbertaAges 18–65 - NCT05024097RecruitingPhase 2
New medicines with chemotherapy after short radiation for rectal cancer
This trial tests two new immune-related medicines (an anti–PD-1 drug and an adenosine blocker) added to standard chemotherapy after a short course of radiation for rectal cancer. It aims to improve cancer control while checking safety.
New York, New YorkAges 18–90 - NCT05008146RecruitingEarly Phase 1
Brain imaging study for cocaine use disorder interactions
This early-phase study uses brain imaging to understand how cocaine use disorder affects brain function. It may help researchers learn more about brain pathways involved in craving and treatment targets.
Pittsburgh, PennsylvaniaAges 18–55 - NCT05004987RecruitingPhase 4
Study brain and blood changes in older adults with depression
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
New York, New YorkAges 60 years+ - NCT05028062RecruitingPhase 4
Naltrexone injections for people who want to cut alcohol drinking
This Phase 4 study tests whether naltrexone injections can help people with alcohol use disorder (AUD) reduce or stop heavy drinking. You may get two injections over 8 weeks, and you can join if you meet specific drinking pattern and eligibility rules.
Philadelphia, PennsylvaniaAges 18–65 - NCT05048212RecruitingPhase 2
Nivolumab, ipilimumab, and cabozantinib for kidney cancer brain spread
This Phase 2 study tests how well nivolumab plus ipilimumab, along with cabozantinib, treats untreated or worsening kidney cancer that has spread to the brain. It may help shrink brain tumors and slow the disease when standard local brain treatments aren’t the right option.
Houston, TexasAges 18 years+ - NCT04930653RecruitingPhase 2
Photopheresis plus mogamulizumab for advanced skin lymphoma
This Phase 2 trial tests whether a combination of photopheresis and the drug mogamulizumab can improve outcomes in adults with advanced mycosis fungoides or Sézary syndrome, which are types of skin T-cell lymphoma. It may help by targeting lymphoma cells in the skin and immune system.
Scottsdale, ArizonaAges 18 years+ - NCT04999553Recruiting
Comparing brain stimulation on left vs right side for depression
This study tests whether delivering a type of brain stimulation to the left side of the head is as effective as delivering it to the right side for treating major depression. The treatment is called transcranial magnetic stimulation (TMS), which uses magnetic pulses to stimulate brain areas involved in mood.
Vancouver, British ColumbiaAges 18–65 - NCT04975152RecruitingPhase 1
Cemiplimab before surgery for Merkel cell and skin cancers
This early-phase study tests cemiplimab (an immune therapy that helps your immune system attack cancer) given before surgery. It aims to shrink tumors and improve outcomes for people with Merkel cell cancer or certain locally advanced skin squamous cell cancers (CSCC).
Tampa, FloridaAges 18 years+ - NCT04991025RecruitingPhase 2
Adding certolizumab to chemotherapy and nivolumab for lung cancer
This study tests whether adding an extra medication, certolizumab, to the usual chemotherapy and an immunotherapy drug called nivolumab can help people with early-stage lung cancer before they have surgery. It aims to see if this combination shrinks the cancer more and improves outcomes.
Basking Ridge, New JerseyAges 18 years+ - NCT04996433Recruiting
Compare two talk therapy programs for treatment-resistant depression
This study compares two psychotherapy programs to help people who have ongoing, difficult-to-treat depression while in inpatient care. If you qualify, you’ll receive one of the therapy programs and be followed to see which approach helps depression symptoms more.
Berlin, State of BerlinAges 18–75 - NCT04858334RecruitingPhase 2
Olaparib after pancreatic cancer surgery for BRCA or PALB2 mutations
This trial studies whether olaparib (a targeted cancer medicine) can help prevent pancreatic cancer from coming back after surgery in people with BRCA1, BRCA2, or PALB2 mutations. You would get olaparib or a placebo (inactive pill) and be closely followed to see if recurrence is reduced.
Anchorage, AlaskaAges 18 years+ - NCT04877093RecruitingPhase 3
Low-dose clonidine for PTSD nightmares in veterans
This Phase 3 study tests whether low-dose clonidine can reduce PTSD symptoms and especially nightmares in U.S. veterans. You’d be screened for PTSD severity and current treatments, then asked to visit the clinic as scheduled to see if the treatment helps.
Wauwatosa, WisconsinAges 18 years+ - NCT04902703RecruitingPhase 2
GM-CSF drug trial for mild to moderate Alzheimer’s disease
This Phase 2 study tests whether sargramostim (a GM-CSF related medicine) is safe and can slow or improve Alzheimer’s symptoms. You might be a good fit if you have mild or moderate Alzheimer’s, positive amyloid testing, and can complete frequent visits with a close caregiver who knows you well.
Aurora, ColoradoAges 60–85 - NCT04860141RecruitingPhase 4
Gabapentin before wisdom tooth removal to reduce pain
This trial tests whether taking gabapentin before extracting a wisdom tooth helps with pain and comfort after the procedure. It may help people who need a third-molar removal, if they meet the safety and health requirements.
Loma Linda, CaliforniaAges 18–59 - NCT04923685Recruiting
Study looks at blood markers linked to childhood trauma and suicide risk
This study checks whether tiny genetic signals in blood (microRNAs) are linked to childhood maltreatment and thoughts or risk of suicide, especially in people with major depression. It may help researchers understand biological clues that could someday guide better care.
Birmingham, AlabamaAges 18–60 - NCT04899544Recruiting
Center vs home therapy for autism with PRT coaching
This study compares two ways of delivering Pivotal Response Treatment (PRT) for young children with autism—at a center or in the home. It may help your child by testing which approach better supports language and autism-related communication skills.
Stanford, CaliforniaAges 2–5 - NCT04858256RecruitingPhase 2
Pacritinib for relapsed or resistant T-cell blood cancers
This Phase 2 trial studies pacritinib, an oral medicine, for T-cell lymphoma/leukemia that has come back or did not respond to prior treatment. It aims to see how well pacritinib can control the cancer and improve outcomes.
Duarte, CaliforniaAges 18 years+ - NCT04898790Recruiting
Testing ways to improve thinking after bone marrow transplant
This study looks at whether a physical activity program and related study measures can improve thinking and memory in older adults around the time of a stem cell transplant. If you qualify and participate, the team will compare outcomes between groups to see what approach works best.
Omaha, NebraskaAges 19 years+
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,350 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.