Clinical trials
Bipolar clinical trials
Below are recruiting bipolar clinical trials, each written for real people, not researchers. We’re tracking 241 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05663008Recruiting
Testing nerve-to-muscle signal changes to diagnose movement diseases
This study measures how nerves communicate with muscles, using recordings and gels. It aims to spot early, personalized signs of conditions like ALS and related diseases, and to improve diagnosis.
Dublin, LeinsterAges 18 years+ - NCT05480826Recruiting
Family genetic study for mood, thinking, and autism conditions
This study looks at genetic changes found in people with conditions like bipolar disorder, schizophrenia, depression, or autism, and compares how those genetic differences may function. It may help researchers understand the causes of these conditions using information from patients and their relatives.
CréteilAges 18 years+ - NCT06417437RecruitingPhase 4
Brain-computer interface test for depression
This trial tests a non-invasive brain-computer interface (BCI) to help people with depression. It may be a good fit for teenagers and adults who are right-handed, Han Chinese, and have moderate to severe depression without other major health problems.
Shanghai, Shanghai MunicipalityAges 12 years+ - NCT07834203Recruiting
State representation in early psychosis study
This study looks at how the brain processes information in people with early psychosis compared to healthy controls. It may help improve understanding and treatment of psychosis.
Minneapolis, MinnesotaAges 15–45 - NCT05409794Recruiting
Testing blood lithium levels in people with depression and suicidality
This study checks how much lithium is naturally present in the blood and whether that relates to suicidal thoughts or attempts in people with a current major depressive episode. It may help researchers understand biological factors linked to suicide risk and improve future prevention.
MontpellierAges 18 years+ - NCT07783633Enrolling by invitation
Digital tools for mood disorders study
This study looks at whether using digital tools, like apps or online programs, can help people with mood disorders like depression or bipolar disorder. It aims to find markers that show who might benefit most from these tools.
Toronto, OntarioAges 16 years+ - NCT07741981Recruiting
Biological markers for treatment-resistant psychiatric disorders
This study looks for biological markers in the blood or spinal fluid that might predict how well a new psychiatric treatment will work. If you have a psychiatric condition that hasn't improved with previous treatments, this research could help find better ways to match treatments to individuals in the future.
ParisAges 18 years+ - NCT06363981Recruiting
Brain stimulation for depression, sleep and memory problems
This study tests a non-invasive brain stimulation treatment (called rTMS) to help with depression, sleep problems, and memory or concentration issues. It's designed for people with moderate to severe depression who also have trouble sleeping and thinking clearly.
KrakowAges 18–65 - NCT06371352Recruiting
Brain stimulation for sleep and fatigue in depression
This study tests a noninvasive brain stimulation treatment (theta burst stimulation) to see if it can improve sleep, reduce daytime sleepiness, and ease fatigue in people with depression.
WarsawAges 18–65 - NCT07713849Recruiting
Transition care for recent psychosis
This study tests a program to help people recently diagnosed with psychosis (within the last two years) transition from hospital to community care. If you have a psychotic disorder and a caregiver involved in your discharge planning, this could help you.
Chicago, IllinoisAges 18–40 - NCT07692984Recruiting
Alcohol and drug use in people with schizophrenia or bipolar disorder
This study looks at how alcohol and substance use affects people with schizophrenia or bipolar disorder. It aims to understand if having these conditions together changes treatment or outcomes.
Bolu, BoluAges 18–65 - NCT07684911Recruiting
Long-term effects of TMS for depression
This study looks at how well the benefits of transcranial magnetic stimulation (TMS) last over time for people with depression that didn't get better with other treatments. It also uses brain scans to find markers that might predict who will keep doing well.
RennesAges 18 years+ - NCT07672093Recruiting
Dry needling for forearm muscle knots
This study tests whether inserting a thin needle (dry needling) into a tight muscle knot in your forearm can help release it without causing pain. It's for healthy adults who have a non-painful knot in their dominant arm.
Reus, TarragonaAges 18–40 - NCT07619092Recruiting
Flumazenil to reverse sedation during depression treatment
This trial tests whether flumazenil (a medication that reverses sedation from anti-anxiety drugs) can safely help patients wake up faster after electroconvulsive therapy (ECT), a treatment for severe depression. The goal is to see if it improves recovery time without causing problems.
Frederiksberg, Capital RegionAges 18 years+ - NCT06729541Recruiting
Precision treatments for common mental disorders
This study is developing more personalized treatments for schizophrenia, depression, or bipolar disorder. It may help find the best treatment approach for your specific situation.
Beijing, Beijing MunicipalityAges 18–65 - NCT07534475Recruiting
Tourniquet Type for Monitoring Brain Activity During ECT
This study compares two types of arm tourniquets (blood-pressure cuffs) used during electroconvulsive therapy (ECT) to help doctors monitor seizure activity more accurately. ECT is a treatment for severe depression and other psychiatric conditions, and tourniquets help track how well the treatment is working.
IstanbulAges 18–65 - NCT07528638Recruiting
Nerve monitoring during breast cancer lymph node surgery
This study tests whether special nerve-monitoring equipment and a specific type of surgical tool can reduce nerve damage during lymph node removal surgery for breast cancer. Researchers want to see if these techniques help preserve arm and shoulder function after surgery.
Cincinnati, OhioAges 18–70 - NCT05958940Recruiting
Bright light therapy study for depression
This trial studies whether daily bright light therapy can reduce depressive symptoms. It’s for adults with depression (including some with bipolar depression), and you would fill out questionnaires and be screened for safety.
EindhovenAges 18–65 - NCT07494305RecruitingPhase 2
Testing a new drug for bipolar depression
This trial tests an investigational drug called LB-102 for people with bipolar I disorder who are currently experiencing a major depressive episode without psychosis. It aims to see if the drug is safe and effective for treating depression symptoms.
Bentonville, ArkansasAges 18–65 - NCT06766838Recruiting
Comparing circumcision methods for young boys
This study compares different circumcision techniques in boys under age 5. It will help doctors understand which method works best.
SohagAges Up to 5 years - NCT07479758Recruiting
Brain scans and vision tests for severe mental illness
This study uses advanced MRI scans and visual perception tests to learn more about severe mental disorders like depression, schizophrenia, and bipolar disorder. It aims to improve diagnosis and treatment outcomes.
Hangzhou, ZhejiangAges 18–45 - NCT07462637Recruiting
Light therapy for depression in unipolar and bipolar disorder
This study tests how well light therapy works for moderate to severe depression in people with or without bipolar disorder. It includes a possible MRI brain scan to understand how light affects the brain. You must not have certain eye conditions or high suicide risk.
ParisAges 18–65 - NCT07411222Recruiting
Emotional Eating, Sleep, and Metabolic Health Study
This study examines how emotional eating, sleep quality, and mental state relate to metabolic syndrome (a group of conditions like high blood pressure, high blood sugar, and extra belly fat) in people with stable schizophrenia or bipolar disorder. It aims to help understand and improve overall health.
Bolu, BoluAges 18–65 - NCT07399626RecruitingPhase 1/Phase 2
Validation of a hypomania risk scale in Romanian
This study adapts and validates a short questionnaire (HPS-6) to measure traits linked to hypomania in Romanian speakers. Participation involves completing surveys, which may help identify early signs of mood changes.
Cluj-NapocaAges 18–50
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Common questions
- Are there clinical trials for bipolar?
- Yes. Clin2 currently lists 241 recruiting bipolar studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.