Clinical trials
Brain Disorder clinical trials
Below are recruiting brain disorder clinical trials, each written for real people, not researchers. We’re tracking 304 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT06426615Recruiting
Understanding brain signals in unresponsive states after injury
This study looks at brain activity in people who are unresponsive after a brain injury. It uses advanced brain scans to see if there are hidden signs of consciousness, which could help doctors better understand and care for these patients.
Leuven, Vlaams-BrabantAges 18 years+ - NCT04524637Recruiting
Testing a clotting test in recent traumatic brain injury
This trial tests whether a special blood clotting test called thromboelastography can help assess clotting problems after a head injury. It may help doctors better understand bleeding risk and related complications early after trauma.
ShanghaiAges 18–80 - NCT02994433RecruitingPhase 1
Testing nitrous oxide for depression brain circuit activity
This early study tests whether nitrous oxide, aimed at specific brain circuits, can change depression-related brain activity. It is mainly for adults with major depression or treatment-resistant depression, and includes brain imaging during the study.
St Louis, MissouriAges 18–65 - NCT06542094Recruiting
Brain stimulation for severe depression that hasn't improved with other treatments
This trial tests if deep brain stimulation (a device that sends tiny electrical pulses to mood-related brain areas) can help people with tough-to-treat depression. It uses brain-signal monitoring to see which patterns predict improvement.
Chengdu, SichuanAges 18–65 - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT04445649Recruiting
Find factors to help people regain consciousness after brain injury
This study looks at what predicts recovery of consciousness after certain serious brain injuries, such as stroke or traumatic brain injury. It may help clinicians better identify which patients are more likely to wake up and guide early rehabilitation and care.
Hessisch OldendorfAges 18–85 - NCT06973512Recruiting
Brain stimulation for severe addiction
This trial tests a new brain stimulation approach for people with severe addiction that hasn't gotten better with other treatments. It uses deep brain stimulation guided by brain mapping to try to reduce cravings and help you stay abstinent.
Toronto, OntarioAges 25–65 - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT06754319Recruiting
Gut bacteria and brain connection in child OCD
This study looks at how the bacteria in your gut might affect OCD in children and teens. It tests a possible link between your gut, brain, and OCD symptoms.
Shanghai, Shanghai MunicipalityAges 7–17 - NCT07858708Enrolling by invitation
Vision problems after brain injury
This study looks at vision problems that can happen after a brain injury, like a stroke, traumatic brain injury, or brain tumor. The researchers want to understand how these vision issues affect daily life, which could help improve care.
Prague, Česká RepublikaAges 18–85 - NCT06914466Recruiting
DBS for sleep problems in Parkinson's disease
This study looks at how deep brain stimulation (DBS) affects sleep problems in people with Parkinson's disease. It aims to understand brain changes and improve sleep quality.
Beijing, Beijing MunicipalityAges 19–80 - NCT07187843Recruiting
Parkinson's type study: brain-first vs body-first
This study looks at how Parkinson's disease affects thinking, movement, and brain health differently depending on whether it starts in the brain or the body first. Participants will have tests and scans to track these differences over time.
Reggio EmiliaAges 18 years+ - NCT05040542Recruiting
Brain scans of social emotions in infants
This study uses brain testing (including MRI scanning) to better understand how young children’s brains support social emotions and communication. It may help researchers learn what brain patterns look like in typical early development.
Xiamen, FujianAges Up to 6 years - NCT07357090Recruiting
Carbon dioxide and brain waste clearance trial
This trial tests if breathing in carbon dioxide helps the brain clear waste. It may show how the brain heals after a traumatic brain injury (TBI).
Albuquerque, New MexicoAges 18–82 - NCT04911738Recruiting
Virtual reality glasses to improve balance after stroke
This trial studies whether virtual reality glasses training can improve balance and body alignment after a recent stroke. It will also compare how stroke participants with balance problems respond versus people without stroke.
GrenobleAges 18–80 - NCT06954610Recruiting
Heart Check for Stroke Risk in Atrial Fibrillation
This trial uses heart imaging to better understand stroke risk in people with atrial fibrillation (an irregular heartbeat). It may help doctors decide on the best treatment to prevent another stroke.
BernAges 18 years+ - NCT06848530Recruiting
Brain activity study in movement disorders
This study looks at brain activity in people with movement disorders like Parkinson's, dystonia, tremor, and ataxia. It aims to better understand how parts of the brain work together, which could lead to better treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06712914Recruiting
Brain stimulation study for hoarding disorder
This study tests a safe, non-invasive brain stimulation method to see if it can help people with hoarding disorder who haven't gotten better with usual treatments. The procedure does not require surgery and is done in a doctor's office.
Palo Alto, CaliforniaAges 18–70 - NCT06469983Recruiting
Robotic vs. traditional standing therapy for severe brain injury
This trial compares using a robotic device versus standard therapy to help people with severe brain injury practice standing. It tests whether the robotic approach leads to better recovery of standing ability.
Sant'Angelo dei Lombardi, AvellinoAges 18–75 - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT06111898Recruiting
Understanding movement in infants at risk
This study looks at how the brain and body work together to control movement in infants who are at high risk for developmental issues. It may help find early signs of motor problems.
GenevaAges 8 months–1 year - NCT07541781RecruitingPhase 1
Sitagliptin for recurrent grade 4 glioma
This trial tests whether the diabetes drug sitagliptin (Januvia) can help slow or shrink a recurrent grade 4 glioma (a type of brain tumor). It's for people whose tumor has come back after standard treatment and who have not used sitagliptin or Avastin before.
Iowa City, IowaAges 18 years+
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Common questions
- Are there clinical trials for brain disorder?
- Yes. Clin2 currently lists 304 recruiting brain disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.