Clinical trials
Brain Disorder clinical trials
Below are recruiting brain disorder clinical trials, each written for real people, not researchers. We’re tracking 311 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06796725Recruiting
Study of TMS for migraine guided by brain imaging
This study tests whether repetitive transcranial magnetic stimulation (rTMS), guided by magnetoencephalography (MEG), can help people with frequent migraines or tension-type headaches. If you have headaches 15 or more days per month, this treatment might reduce your pain.
ShanghaiAges 15–50 - NCT06819657Recruiting
Remote ischemic conditioning after aneurysm surgery
This trial tests a safe, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff on your leg) to see if it helps brain recovery after aneurysm surgery. It might reduce secondary damage and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06959199Recruiting
Treating stroke beyond 24 hours with artery-opening procedure
This study tests whether opening a blocked large artery in the brain up to 5 days (or even 7 days if symptoms are worsening) after a stroke can improve outcomes. It uses a catheter-based treatment (endovascular therapy) for people who have not responded to standard care and have limited brain damage so far.
Hefei, AnhuiAges 18 years+ - NCT07185022Recruiting
Clot-busting drug through artery for medium-vessel stroke
This trial tests a clot-busting drug given directly into the arteries of the brain for people who have had a stroke due to a blockage in a medium-sized artery. It aims to see if this treatment can help improve recovery when started up to 72 hours after symptoms begin.
Fuyang, AnhuiAges 18 years+ - NCT07541781RecruitingPhase 1
Sitagliptin for recurrent grade 4 glioma
This trial tests whether the diabetes drug sitagliptin (Januvia) can help slow or shrink a recurrent grade 4 glioma (a type of brain tumor). It's for people whose tumor has come back after standard treatment and who have not used sitagliptin or Avastin before.
Iowa City, IowaAges 18 years+ - NCT06072079Enrolling by invitation
Structural chromosome changes and brain disorders
This trial is for people who have or might have a rare disease or a change in their chromosomes. The study aims to learn more about how these changes relate to brain disorders.
StockholmAges Any age - NCT01581580Recruiting
Deep brain stimulation surgery for movement disorders
This study looks at whether deep brain stimulation surgery can help people with certain movement problems, chosen by a specialized team. You may be considered if medicines (or other treatments) aren’t controlling your symptoms well enough or if the condition causes major disability.
Bethesda, MarylandAges 18–99 - NCT06518785Recruiting
Ultrasound brain treatment for alcohol use disorder
This study tests if focused ultrasound can help reduce alcohol cravings by stimulating a specific part of the brain. Participants will receive ultrasound treatments and undergo an MRI to see how the brain responds.
San Francisco, CaliforniaAges 18 years+ - NCT06604000Recruiting
Goal management training for cognitive control after brain injury
This trial tests a training program called Goal Management Training (GMT) to help people who have had a brain injury improve their ability to plan, focus, and stay organized. If you have trouble with these skills and your injury happened at least a year ago, this training might help you get better at everyday tasks.
TrondheimAges 18–65 - NCT07671261Recruiting
Brain surgery for schizophrenia guided by electrode mapping
This trial tests whether deep brain stimulation (DBS) guided by SEEG (a way to map brain activity with electrodes) can help treat schizophrenia. It is for people with moderate to severe symptoms who have not improved after trying at least two different antipsychotic medications.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT06819592RecruitingPhase 3
Preventing early lung infections after severe brain injury
This study tests whether giving an antibiotic (ceftriaxone) early after a severe brain injury can prevent lung infections caused by the breathing machine (ventilator). It is for adults in the ICU who recently started on a ventilator due to a brain emergency.
Kingswood, New South WalesAges 18 years+ - NCT07677046Enrolling by invitation
Combination therapy for complex dissociative disorder
This trial studies a therapy called Deep Brain Reorienting (DBR) combined with group sessions for people with complex dissociative disorder, such as dissociative identity disorder (DID) or other specified dissociative disorder (OSDD). The goal is to help process trauma in a safe and supportive setting.
Oslo, OsloAges 18 years+ - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT02537795Recruiting
Talking about OCD care after brain stimulation
This study explores what patients with OCD and their family members experience after they’ve had a surgery-based treatment called deep brain stimulation or anterior capsulotomy. Your feedback may help researchers understand what support and outcomes matter most to families and patients.
Leuven, Vlaams-BrabantAges Any age - NCT05265546RecruitingPhase 1
Psilocybin study of changes in how you see
This Phase 1 study tests whether psilocybin affects visual perception and how visual information is represented in the brain. It also studies safety and what brain/vision changes happen after the dose.
Berkeley, CaliforniaAges 21 years+ - NCT03170440Recruiting
Non-invasive nerve stimulation for PTSD and sleep
This study tests a non-invasive way to stimulate nerves without surgery in people with PTSD, especially looking at sleep and related symptoms. It may help by improving how your nervous system and sleep patterns work over time.
Gainesville, FloridaAges 18–55 - NCT03990909Recruiting
BCAA supplements to help improve sleep
This pilot study tests whether taking BCAA supplements can improve sleep problems. You may be able to join if you’re a veteran with sleep issues and can do the study by phone.
Portland, OregonAges 18–89 - NCT04550377RecruitingPhase 2
Cannabidiol for PTSD, including PTSD after mild head injury
This Phase 2 study tests whether cannabidiol (CBD) can reduce PTSD symptoms, including in people who also had a mild traumatic brain injury (TBI). It’s meant to see if CBD is helpful and safe for PTSD symptoms over the study period.
New York, New YorkAges 18–70 - NCT05417555Recruiting
Focused ultrasound for mild memory problems and early Alzheimer’s
This trial studies whether a low-intensity focused ultrasound treatment can improve brain function in people with mild cognitive impairment (early memory decline) or mild Alzheimer’s disease. It may help slow symptoms or improve how the brain works, but it’s still being tested.
Los Angeles, CaliforniaAges 50–90 - NCT05916417Recruiting
Personalized TMS dosing for PTSD using brain monitoring
This study tests a “personalized dosing” approach for transcranial magnetic stimulation (TMS) in adults with PTSD. It aims to see whether using brain measurements to guide the TMS settings can improve treatment while keeping participants safe.
Tallahassee, FloridaAges 18–70 - NCT06270290Recruiting
Concussions and contact sports in RBD patients versus controls
This trial looks at whether people with REM sleep behavior disorder (RBD) have more concussions or contact sports history than people without RBD, to see if head injuries might be linked to the condition.
London, LondonAges 50 years+ - NCT06494319Recruiting
PTSD treatment app for veterans with combat trauma
This study tests a virtual training program and mobile app to help veterans manage PTSD from combat. It aims to reduce symptoms and improve daily life.
Houston, TexasAges 18–79 - NCT07521930Recruiting
Brain implant to restore communication and movement control
This trial tests a surgically implanted brain device designed to help people with severe paralysis or movement disorders regain the ability to communicate and control their limbs. The device reads signals from your brain and translates them into commands that could help you interact with computers or assistive technology.
Baltimore, MarylandAges 18–80 - NCT06635291Recruiting
Better Diagnosis for Children with Brain Injury
This study tests new ways to evaluate children with severe brain injuries who are in a vegetative or minimally conscious state. The goal is to improve diagnosis and care for children with serious disorders of consciousness after a brain injury.
Bosisio Parini, LeccoAges 2 months–25 years
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Common questions
- Are there clinical trials for brain disorder?
- Yes. Clin2 currently lists 311 recruiting brain disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.