Clinical trials
Brain Disorder clinical trials
Below are recruiting brain disorder clinical trials, each written for real people, not researchers. We’re tracking 311 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06147999Recruiting
Biophoton therapy for brain disorders
This trial tests a biophoton therapy, a light-based treatment, for people with brain disorders. It aims to see if this non-invasive approach can help improve symptoms.
Butler, PennsylvaniaAges 18 years+ - NCT06837324Recruiting
Smart glove therapy for arm weakness after brain injury
This study tests a smart glove system that provides arm and hand exercises at home for people who had a brain injury (like a stroke) more than 3 months ago and have weakness on one side. The goal is to improve use of the affected arm without needing frequent hospital visits.
SeoulAges 19–85 - NCT06837363Recruiting
Smart board rehab for arm weakness after brain injury
This trial tests a smart board therapy that you can do without in-person contact to help improve arm movement if you have weakness on one side from a stroke, brain injury, or tumor. It is for people who are at least 3 months past their diagnosis and can understand simple instructions.
SeoulAges 19–85 - NCT06716489Recruiting
Exercise study for women with migraine
This study tests whether aerobic exercise can help reduce migraine symptoms and improve how your body senses and responds to pain. It is specifically for women aged 18–48 who have migraine headaches 3–8 days per month.
Ribeirão Preto, São PauloAges 18–48 - NCT06866379Recruiting
Brain study on alcohol use disorder: septal nuclei
This study uses brain scans (fMRI) to look at a small area deep in the brain called the septal nuclei, which may play a role in alcohol use disorder. It aims to understand how the brain's structure and activity relate to heavy drinking, which could lead to better treatments.
FrederiksbergAges 30–65 - NCT06115291Enrolling by invitation
Smell training study for adults with smell loss
This study tests whether a daily smell training routine can help improve your sense of smell. It is open to adults with any kind of smell loss or problem, including those with conditions like COVID-19 or head injury, but not certain brain diseases.
Kansas City, KansasAges 18–80 - NCT07435610Recruiting
Acupuncture for children with stomach pain and related issues
This study tests whether acupuncture can help children with stomach pain or other gut-brain interaction disorders. It may be a good option if your child's current treatments aren't working well enough.
Irvine, CaliforniaAges 8–17 - NCT06542224Recruiting
Finding Brain Signals to Guide OCD Deep Brain Stimulation
This study is testing whether brain signals measured during deep brain stimulation (DBS) can help doctors better treat Obsessive-Compulsive Disorder. It may offer a new way to personalize treatment for people with severe, treatment-resistant OCD.
Chengdu, SichuanAges 18–65 - NCT05892510RecruitingPhase 2/Phase 3
Tenecteplase after clot removal for no-reflow stroke
This trial tests whether giving tenecteplase directly into the brain artery after a thrombectomy can improve outcomes when blood flow doesn’t fully return (“no-reflow”) in an emergency stroke. It may help some people by reducing ongoing clot-related blockage after the main clot is removed.
Gold Coast, QueenslandAges 18 years+ - NCT07214467Recruiting
Adaptive brain stimulation for opioid use disorder
This study tests a new type of brain stimulation that adapts to your brain activity, aiming to reduce cravings and help you control opioid use. It is for people with long-standing opioid use disorder who have not gotten lasting relief from at least 3 treatment attempts, including medication.
San Francisco, CaliforniaAges 22–75 - NCT00041600Recruiting
Brain Development and Genetic Study for Family Members
This research study investigates how genetic factors affect brain development and function in families where members have brain malformations, intellectual disability, or autism. Researchers hope to identify genetic causes that could lead to better understanding and future treatments.
Boston, MassachusettsAges Any age - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT06851156Recruiting
Brain stimulation for disorders of consciousness after severe injury
This trial tests a new type of brain stimulation called transcranial temporal interference stimulation to see if it can help people with severe brain injury who are in a vegetative or minimally conscious state. It uses gentle electrical currents to try to improve awareness and recovery.
Xi'an, ShaanxiAges 18–65 - NCT05065450Recruiting
Testing whether brain stimulation improves memory in epilepsy
This trial looks at ways to improve memory by targeting specific deep brain areas in people with epilepsy. You may be eligible if you are already scheduled for long-term video monitoring with implanted depth electrodes in the memory-related regions (amygdala, hippocampus, and nearby areas).
St Louis, MissouriAges 18–75 - NCT03586258Recruiting
Brain scan and memory testing for people with brain injury
This study uses memory and thinking tests along with brain scans (likely MRI) to understand how different types of brain damage affect thinking. It may help doctors learn more about brain-related cognitive problems.
CaenAges 18 years+ - NCT07048002Recruiting
Silent brain infarct and cognitive decline after heart surgery
This trial tests a bundle of interventions to prevent silent brain infarctions (small 'silent' strokes) and thinking problems after heart or blood vessel surgery with a heart-lung machine. If you are 60 or older and having such surgery, this study may help protect your brain health.
Beijing, Beijing MunicipalityAges 60 years+ - NCT06628752Recruiting
Deep brain stimulation for severe OCD
This study tests a treatment called deep brain stimulation (DBS) for people with severe OCD that hasn't improved with standard therapies. DBS uses a device to send small electrical pulses to specific parts of the brain to help control symptoms.
Umeå, Västerbotten CountyAges 18–65 - NCT04442971Recruiting
Music therapy for consciousness recovery after brain injury
This trial studies whether music therapy can help improve the level of consciousness in people recovering from a traumatic brain injury. If you are in early neurological rehabilitation, it may be offered as an add-on approach to support recovery.
Hessisch OldendorfAges 18–85 - NCT07140601Recruiting
Environmental pollutants and brain health study
This study looks at how environmental pollutants might affect brain health and neurological disorders. If you join, you will help researchers understand possible links between pollution and conditions like Parkinson's or Alzheimer's.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07324330Recruiting
Slowing cognitive decline with exercise in iRBD
This study tests if increasing physical activity can help slow down cognitive (thinking) decline in people with iRBD, a sleep disorder that often leads to Parkinson's or dementia. You'll use a smartphone and a FitBit to track your activity and receive coaching.
Bonn, North Rhine West-FaliaAges 50–80 - NCT07056361Recruiting
Testing brain stimulation for better movement in tremor and Parkinson's
This study tests whether stimulating specific brain areas (VOP/VIM) during deep brain stimulation surgery can improve movement and muscle control. It includes people with essential tremor or Parkinson's disease who are already scheduled for this surgery.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07033923Recruiting
Brain study of mood changes in depression and bipolar disorder
This study uses a mobile app and brain scans to understand day-to-day mood changes in people with depression or bipolar disorder. It may help doctors learn how to better predict and treat these conditions.
Paris, ParisAges 18 years+ - NCT04322734Recruiting
Blood tests study immune and metabolism markers in neurodevelopment
This study looks for biological “signals” in blood—related to the immune system and metabolism—to better understand conditions like autism and other brain or development-related disorders. It may help researchers find markers that could guide future diagnosis or treatment.
Phoenix, ArizonaAges Up to 18 years - NCT06112067Recruiting
Brain implant for severe mental health conditions
This trial tests a brain implant called deep brain stimulation (DBS) for people with severe mental health conditions that have not improved with usual treatments. The goal is to see if it can reduce symptoms and improve quality of life.
ShanghaiAges 18–65
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Common questions
- Are there clinical trials for brain disorder?
- Yes. Clin2 currently lists 311 recruiting brain disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.