Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05691439Recruiting
Sleep Timing, Mood, and Brain Circuits in Teens With Depression
This study looks at how sleep timing affects brain function related to mood and “pleasure” in teenagers who have depressive symptoms. It may help researchers understand why depression and reduced interest/pleasure can happen, and how sleep patterns might be a key factor.
Eugene, OregonAges 14–18 - NCT07374913Recruiting
Study of COL4A1 and COL4A2 gene mutations
This study looks at people with a mutation in the COL4A1 or COL4A2 genes, which can cause problems in small blood vessels throughout the body. It aims to learn more about the condition and may also include family members who carry the mutation or who can serve as healthy controls.
Florence, FIAges Any age - NCT06788808Recruiting
Ultrasound study of fetal brain development in pregnancy
This study uses ultrasound to examine fetal brain and spine development in pregnant women. It compares scans from pregnancies where a brain or spine issue is suspected with those from healthy pregnancies to improve understanding and diagnosis.
Bologna, BolognaAges 18–45 - NCT07696598Recruiting
Brain bleed surgery study in children after head injury
This study looks at how children under 18 do after surgery for a specific type of brain bleed (called an extradural or epidural hematoma) caused by a head injury. The goal is to understand what helps them heal better.
Sohag, Sohag GovernorateAges 1 day–18 years - NCT07378332Enrolling by invitation
Memory study using brain stimulation
This trial uses brain stimulation to study how memory works. It may help people undergoing epilepsy monitoring learn more about their memory.
Chicago, IllinoisAges 18 years+ - NCT05357456Recruiting
Study of brain and memory changes in cortisol-producing adrenal conditions
This study tracks thinking and brain changes over time in people with adrenal findings that produce too much cortisol (a stress hormone) on their own. It may help doctors understand how different treatments or watchful waiting affect the brain and cognition.
Nanjing, JiangsuAges 20–65 - NCT05801861Recruiting
Brain stimulation study for goal-based navigation skills
This study tests whether noninvasive brain stimulation can improve how people plan and navigate toward a goal. It also uses brain scans and questionnaires to see who may benefit and whether the stimulation is safe for you.
Newark, New JerseyAges 18–55 - NCT07287527Recruiting
Light therapy for memory and brain health
This study tests whether a type of light therapy called photobiomodulation can improve brain connections and thinking abilities in people with mild memory problems.
IstanbulAges 55 years+ - NCT06022055Recruiting
studying brain tissue from epilepsy surgery
This study collects brain tissue from people with epilepsy that is not controlled by medication, during their planned surgery. Researchers will study the tissue to better understand epilepsy and improve treatments.
ParisAges 18 years+ - NCT07279831Recruiting
Brain-lung interaction study in acute respiratory failure
This trial looks at how the lung and brain communicate during serious breathing problems. If you are in the ICU with a new breathing issue and need high-flow oxygen therapy, researchers want to study your brain and lung activity together.
ParisAges 18 years+ - NCT07252011Recruiting
Brain stimulation study for mood swings
This study tests a non-invasive electrical stimulation method to help people with mood swings. It aims to improve mood stability and brain function.
Pittsburgh, PennsylvaniaAges 18–65 - NCT07234890RecruitingPhase 2
Testing AV-001 to protect the brain during hemodialysis
This study tests a new medicine called AV-001 to see if it can protect the brain from damage caused by hemodialysis. If you qualify, you may help find a way to reduce thinking and memory problems linked to dialysis.
London, OntarioAges 18 years+ - NCT06526572Recruiting
Pain measurement with brain waves in tooth infection
This trial tests a new way to measure pain from a tooth infection using brain wave recordings (EEG). It may help people whose numbing injection doesn't work well.
Cleveland, OhioAges 18–50 - NCT07223645Recruiting
Handgrip exercise and brain blood flow in young adults
This study tests whether a simple handgrip exercise program can improve blood flow regulation to the brain in young adults who are not very active. Participants will do handgrip exercises at home using a mobile app to track their progress.
Tallahassee, FloridaAges 18–35 - NCT07208734Enrolling by invitation
Personalized brain stimulation for memory loss in older adults
This trial tests a personalized brain stimulation treatment for older adults with mild memory or thinking problems caused by Alzheimer's disease. It aims to see if tailored stimulation can improve cognitive function.
Beijing, Beijing MunicipalityAges 50–90 - NCT07208318RecruitingEarly Phase 1
Restructuring brain signals for aging vision
This study tests a new way to help older adults improve their vision by retraining how the brain processes visual information. It may help with age-related vision changes.
Boston, MassachusettsAges 18 years+ - NCT03514524Enrolling by invitation
PET-MRI brain scans for recent injury, stroke, or mild memory changes
This study uses special brain scans to measure proteins and connections in the brain after a recent injury, stroke, or in people with mild memory/behavior changes. The goal is to understand brain changes and how they relate to symptoms, which may help future diagnosis and treatment.
LeuvenAges 18–80 - NCT07190365Recruiting
Goal-oriented telehealth rehab for veterans with brain injury
This trial tests a telehealth program to help veterans with long-term thinking and planning problems after a mild to moderate brain injury. It aims to improve your daily life and community involvement.
Palo Alto, CaliforniaAges 18–65 - NCT07092995Enrolling by invitation
Understanding freezing of gait in Parkinson's using VR and brain signals
This study uses virtual reality and brain recordings from your DBS device to understand why some people with Parkinson's experience freezing of gait (feeling like your feet are stuck to the ground). You'll be asked to walk in a safe VR environment while researchers monitor your brain activity.
Los Angeles, CaliforniaAges 18 years+ - NCT06583252Recruiting
Monitoring care for severe traumatic brain injury
This study tests a special monitoring approach for people with severe traumatic brain injury who are not opening their eyes or following commands. The goal is to see if close watching and coordinated care can improve recovery.
Changsha, HunanAges 18 years+ - NCT03609112Recruiting
Study brain and thinking risks in children with solid tumors
This study looks at how cancer treatment may affect children’s thinking and brain health. It may help doctors better understand risks so they can monitor and support learning and memory during and after treatment.
Villejuif, Val De MarneAges Any age - NCT07023640Recruiting
Imaging test for tumors using a new tracer agent
This trial tests a new imaging method (68Ga-DOTA-mPNE PET/CT) to see if it can help detect cancers. It's for people who haven't had chemotherapy or radiation yet and will have a biopsy or surgery.
Beijing, Beijing MunicipalityAges 18–70 - NCT06741085RecruitingPhase 2
Radiosurgery plus standard care for lung cancer spread to brain
This trial tests if adding stereotactic radiosurgery (focused radiation) to standard drug therapy is safe and effective for people with EGFR-mutant non-small cell lung cancer that has spread to the brain. It aims to improve control of brain metastases while continuing targeted therapy.
Miami, FloridaAges 18 years+ - NCT07010887Recruiting
Soccer heading and your brain
This study looks at how different intervals of heading a soccer ball affect your brain health. You might be eligible if you're a current soccer player with several years of heading experience and no recent head or eye problems.
Bloomington, IndianaAges 18–35
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.