Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07216222Recruiting
Brain response study for epilepsy or PTSD patients
This study looks at how the brain processes fear using a device already implanted to treat epilepsy or PTSD. It may help researchers understand fear responses and improve treatments.
Los Angeles, CaliforniaAges 18–70 - NCT07215910RecruitingPhase 3
Testing vorasidenib with temozolomide after radiation for advanced brain cancer
This trial tests whether adding the targeted drug vorasidenib to standard chemotherapy (temozolomide) after radiation helps people with a specific type of advanced brain cancer called IDH-mutant astrocytoma. It is for patients who have not had previous treatments like chemotherapy or radiation and whose tumors have certain genetic features.
Bakersfield, CaliforniaAges 12 years+ - NCT07220265Recruiting
PKU carriers: How high phenylalanine affects the brain
This study looks at how carrying one copy of the PKU gene might affect thinking and brain health in adults. It will help researchers understand if mild changes in a substance called phenylalanine can impact memory, focus, and brain scans.
Columbia, MissouriAges 18–60 - NCT07215221Recruiting
TBI screening in substance use treatment
This study tests a new way to screen for traumatic brain injury (TBI) among people receiving substance use treatment. If you are in outpatient therapy for substance use, you may be able to join.
Columbus, OhioAges 18 years+ - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT05182892Recruiting
Reducing speech side effects from DBS using speech recordings
This study tests whether automated analysis of your speech can help reduce speech problems caused by deep brain stimulation (DBS) in Parkinson’s disease. It may help your team adjust DBS settings to improve how you speak while keeping Parkinson symptoms controlled.
PragueAges 18 years+ - NCT06883006RecruitingPhase 1
Sleep extension study for recent concussion recovery
This trial tests whether extending sleep helps young adults recover from a recent concussion. If you are 18-35 and had your first or second concussion 2-3 weeks ago, you may be able to join.
North Andover, MassachusettsAges 18–35 - NCT06922487Recruiting
Tiredness study during awake brain tumor surgery
This trial looks at tiredness during awake brain surgery for tumor removal. It might help understand how awake procedures affect patients.
LundAges 18 years+ - NCT06922500Recruiting
Brain-Wave Monitoring During Brain Tumor Surgery
This study tests a special brain-wave monitor (called processed EEG) during surgery to remove a brain tumor. The monitor helps the anesthesiologist keep you at the right level of sleep, which may improve safety and recovery.
LundAges 18 years+ - NCT06779487Recruiting
Predicting memory changes from brain radiation
This study looks for biomarkers in your blood that might predict how radiation treatment affects brain function. The goal is to understand and possibly reduce cognitive side effects.
Mumbai, MaharashtraAges 5–39 - NCT05968976Recruiting
DBS surgery guided while awake versus asleep for essential tremor
This study compares two ways of doing a deep brain stimulation (DBS) procedure for people with essential tremor: using guidance while you are awake versus while you are asleep. It aims to find which approach is safer and works better for controlling disabling tremor.
Amsterdam, North HollandAges 18 years+ - NCT05213169RecruitingPhase 2/Phase 3
Apomorphine for severe unresponsive brain injuries
This trial tests whether apomorphine can improve care or outcomes for people in an unresponsive wakefulness or minimally conscious state after a brain injury. It is designed for patients who are medically stable and not currently on certain brain- or heart- affecting medicines.
Liège, LiegeAges 18–80 - NCT06922409Recruiting
Light therapy for stroke recovery in rehabilitation
This trial tests whether exposure to naturalistic light can help reduce fatigue and depression after a stroke. It is designed for patients in a rehabilitation unit who are able to communicate and cooperate with simple physical exams.
Glostrup Municipality, Capital RegionAges 18 years+ - NCT07209657Recruiting
Familiar songs for children with brain injury
This study tests whether listening to familiar songs can increase awareness in children with disorders of consciousness after a severe brain injury. Your child may be eligible if they are in a low-responsive state and you can give consent.
Parkville, VictoriaAges 1–18 - NCT07208318RecruitingEarly Phase 1
Restructuring brain signals for aging vision
This study tests a new way to help older adults improve their vision by retraining how the brain processes visual information. It may help with age-related vision changes.
Boston, MassachusettsAges 18 years+ - NCT07208734Enrolling by invitation
Personalized brain stimulation for memory loss in older adults
This trial tests a personalized brain stimulation treatment for older adults with mild memory or thinking problems caused by Alzheimer's disease. It aims to see if tailored stimulation can improve cognitive function.
Beijing, Beijing MunicipalityAges 50–90 - NCT03276793Recruiting
Brain connectivity study in people with depression
This study looks at brain “connectivity” (how different brain areas talk to each other) in people with depression. You may be able to join if you are already getting once-daily TMS to a specific brain area at Brigham and Women’s or Massachusetts General, and you can safely complete MRI scans.
Boston, MassachusettsAges 18 years+ - NCT07196462Recruiting
Brain stimulation to reduce cannabis craving in schizophrenia
This study tests if a non-invasive brain stimulation technique can help reduce cravings for cannabis in people with schizophrenia. It aims to see if this approach can improve outcomes for those who use cannabis and have a psychotic disorder.
Nashville, TennesseeAges 18–65 - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT06207942Recruiting
Extended follow-up for cardiac arrest survivors and caregivers
This study follows up on survivors of out-of-hospital cardiac arrest who were already in the STEPCARE trial. It also looks at the well-being of their main caregiver (like a family member or close friend) to see how everyone is doing over time.
BrisbaneAges 18 years+ - NCT06909071Recruiting
Smart insulin pump for blood sugar control after brain surgery
This trial tests a smart insulin pump (hybrid closed-loop system) to control high blood sugar after brain surgery for bleeding strokes. It's for people with type 2 diabetes who are stable enough to leave the intensive care unit and are getting tube feedings.
Taiyuan, ShanxiAges 18–75 - NCT06942559Recruiting
Brain stimulation for treatment-resistant OCD
This trial tests a new type of brain stimulation (TMS) that is timed to your brain's natural rhythms, targeting a part of the brain linked to OCD. It may help people whose OCD has not improved with standard treatments.
Toronto, OntarioAges 18–65 - NCT05907317RecruitingPhase 3
Protecting the brains of very young newborns on breathing machines
This Phase 3 study tests ways to protect brain health in newborns who are very premature or recently born and need a breathing machine through a tube. It may help reduce the risk of brain injury while they receive intensive care.
MadridAges birth–4 weeks - NCT07190365Recruiting
Goal-oriented telehealth rehab for veterans with brain injury
This trial tests a telehealth program to help veterans with long-term thinking and planning problems after a mild to moderate brain injury. It aims to improve your daily life and community involvement.
Palo Alto, CaliforniaAges 18–65
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.