Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06140875Recruiting
Radiofrequency treatment plus standard therapy for glioblastoma
This trial tests whether adding a special type of radiofrequency electromagnetic field treatment to standard chemotherapy and radiation therapy helps people with newly diagnosed glioblastoma. It is for patients who are planning to receive standard treatment and have had surgery to remove the tumor.
BerlinAges 18–70 - NCT06142435Recruiting
Eye scan to detect and monitor mild brain injury
This study uses a retinal scanner to see if it can detect and track brain injury after a mild head trauma (concussion). If you are between 18 and 45 years old and had a head injury within the past two weeks, this test might help doctors learn more about your injury without invasive procedures.
Boston, MassachusettsAges 18–45 - NCT06146725Recruiting
Resection vs. biopsy in high-grade glioma patients
This study compares whether having surgery to remove as much of the tumor as possible (resection) or just taking a small sample (biopsy) leads to better outcomes for people with a fast-growing brain tumor (high-grade glioma). The goal is to help guide treatment decisions.
San Francisco, CaliforniaAges 18–90 - NCT06148324Recruiting
Wellness program for traumatic brain injury recovery
This study tests a wellness program for people who had a moderate or severe traumatic brain injury (TBI) at least a year ago. The program is done online, so you can join from home, and it aims to help you with your recovery and well-being.
New York, New YorkAges 18–70 - NCT06150352Recruiting
Sleep apnea and memory in older adults with mild concerns
This trial looks at how sleep apnea affects memory and brain health in people who have mild memory problems or are worried about their memory. You will have a sleep study and brain scans to see if treating sleep apnea could help protect your thinking skills.
Hong KongAges 50–80 - NCT06157008Recruiting
Brain networks and anesthesia in consciousness disorders
This study looks at how anesthesia affects brain networks in people with prolonged disorders of consciousness. It uses a spinal stimulator and sleep recordings (PSG) to understand brain activity better and may help improve treatment.
BeijingAges 18–65 - NCT06157866Recruiting
Cognitive training with acupuncture for fibromyalgia pain
This study tests whether a type of mental training (cognitive training) can help your brain respond better to acupuncture for fibromyalgia pain. You would receive acupuncture while doing a thinking task, and the study will use brain scans to see how your brain changes.
Charlestown, MassachusettsAges 18–65 - NCT06161974RecruitingPhase 2
Olutasidenib and temozolomide for IDH1-mutant high-grade glioma
This trial tests a combination of two oral medications, olutasidenib and temozolomide, for people with a specific type of aggressive brain tumor (high-grade glioma) that has an IDH1 mutation. The goal is to see if this combination can help control the tumor after standard treatment like radiation.
Aurora, ColoradoAges 12–39 - NCT06163625Recruiting
Brain activity and memory in treatment-resistant depression
This study looks at how the brain's frontal lobe (DLPFC) works during memory tasks in people with treatment-resistant depression. It compares brain activity between depressed patients and healthy controls using MRI and possibly a brain stimulation technique (rTMS). It aims to understand why some people don't respond to standard treatments.
Toronto, OntarioAges 18–65 - NCT06164314Recruiting
Calming medicine during brain tumor surgery
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
BeijingAges 18 years+ - NCT06176092Recruiting
Brain health study for healthy adults
This study is looking at how the brain works in healthy younger and older adults. You will participate in tasks and assessments that help researchers understand decision-making and brain function.
Orlando, FloridaAges 20 years+ - NCT06183658Recruiting
Healthy Brain Aging Study for Adults 55–90
This study looks at healthy brain aging in older adults. It involves brain scans, blood tests, and regular check-ins to understand how memory and thinking change over time.
Shenzhen, OtherAges 55–90 - NCT06189950Recruiting
Testing a new stent for wide-necked brain aneurysms
This trial is testing a new stent (a small mesh tube) designed to treat wide-necked brain aneurysms. If you have this type of aneurysm, the stent helps hold coils in place to block blood flow and prevent rupture.
Zhengzhou, HenanAges 18–80 - NCT06192342Recruiting
Breathing machine settings for brain injury patients
This study looks at how different breathing machine settings affect people with new brain or spinal cord injuries who need help breathing. It only includes people with healthy lungs to see which ventilator settings work best.
Ciudad Autonoma de Buenos Aires, Buenos AiresAges 16 years+ - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT06195345Recruiting
Brain oxygen study for children having an MRI
This study looks at oxygen levels in the brains of children and young adults (birth to 18 years) during a standard MRI. The goal is to learn more about how the brain works, and it only adds a few minutes to your child's regular MRI scan.
Los Angeles, CaliforniaAges 1 minute–18 years - NCT06197698Recruiting
Parkinson's and gut-brain connection study
This study is looking at how the bacteria in your gut might affect your brain in Parkinson's disease. It involves two types of brain scans to see differences between people with Parkinson's and healthy volunteers.
DouliuAges 20 years+ - NCT06203626Recruiting
Portable MRI for brain imaging at the bedside
This study is testing a new, portable MRI machine that can be used right at your bedside. It aims to see if it can take clear pictures of the brain for people with strokes, brain conditions, or symptoms of a brain problem.
Bethesda, MarylandAges 3–99 - NCT06207591Recruiting
Brain implant study for locked-in communication
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
UtrechtAges 18–70 - NCT06207942Recruiting
Extended follow-up for cardiac arrest survivors and caregivers
This study follows up on survivors of out-of-hospital cardiac arrest who were already in the STEPCARE trial. It also looks at the well-being of their main caregiver (like a family member or close friend) to see how everyone is doing over time.
BrisbaneAges 18 years+ - NCT06208657RecruitingPhase 1/Phase 2
Personalized cancer therapy for kids and teens
This trial tests personalized cancer treatments for children and teens whose cancer has not responded to standard therapy. It uses information from precision medicine studies to match the right drug to each child's tumor.
Newcastle, New South WalesAges birth–21 years - NCT06208813Recruiting
Creatine for Concussion Recovery in Young Adults
This study tests whether taking creatine (a natural muscle supplement) can help young adults recover faster after a concussion. The trial starts very soon after injury, within the first 3 days.
San Diego, CaliforniaAges 18–35 - NCT06212609Recruiting
Personalized brain stimulation for kids with hard-to-control epilepsy
This trial tests a personalized brain stimulation method (transcranial electrical stimulation) to reduce seizures in children with hard-to-control partial epilepsy. It aims to find the best stimulation spot and settings for each patient by using advanced brain scans.
AmiensAges 1–18 - NCT06221553RecruitingPhase 1
New CAR T-cell treatment for DIPG brain tumor
This trial tests a new type of immunotherapy called B7H3 IL-7Ra CAR T-cells for children with DIPG, a tough-to-treat brain tumor. The treatment is given directly into the fluid around the brain using a special catheter, and the goal is to see if it's safe and if it can help fight the tumor.
Bangkok, PathumwanAges 1–18
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.