Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06221631Recruiting
Brain aging in MS and healthy people
This study compares how the brain ages in people with multiple sclerosis (MS) and healthy volunteers. It uses MRI scans and other tests to understand brain aging better.
Bern, Canton of BernAges 18–65 - NCT06222450Recruiting
Vestibular rehab app for dizziness after mild brain injury
This study tests a smartphone app with exercises to help improve balance and dizziness in people who have had a mild traumatic brain injury. You may be eligible if you are still experiencing dizziness or balance problems.
Tampa, FloridaAges 18 years+ - NCT06229483RecruitingPhase 3
Does tranexamic acid reduce bleeding during brain tumor surgery?
This study tests whether a medication called tranexamic acid (TXA) given during brain tumor surgery can reduce bleeding. If you are having a standard craniotomy for a tumor and don’t have certain health risks, you may be eligible.
Halifax, Nova ScotiaAges 18–80 - NCT06231186Recruiting
Study of iHD-SRT for brain metastases
This study tests a new type of radiation therapy (iHD-SRT) for people with brain metastases. It aims to see if this approach is safe and effective for treating tumors that have spread to the brain.
Shanghai, Shanghai MunicipalityAges Any age - NCT06236503Recruiting
Brain stimulation for minimally conscious state
This trial tests a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) to see if it can help people in a minimally conscious state. The goal is to improve awareness and responsiveness.
Messina, ItaliaAges 18–75 - NCT06238882Recruiting
Nitroglycerin plus radiation for EGFR-mutant lung cancer with brain spread
This trial tests whether adding nitroglycerin (a medicine that widens blood vessels) to standard whole-brain radiation helps improve treatment for lung cancer that has spread to the brain. It is for people with a specific gene change (EGFR mutation) in their cancer.
Mexico City, Mexico CityAges 18–85 - NCT06238921RecruitingPhase 1/Phase 2
Study of two drugs and radiation for triple-negative breast cancer that spread to the brain
This trial tests adding the drugs sacituzumab govitecan and zimberelimab to targeted radiation therapy for people with triple-negative breast cancer that has spread to the brain. The goal is to see if this combination helps control the cancer longer.
Tampa, FloridaAges 18 years+ - NCT06241209Recruiting
Vision rehab for hemianopsia after stroke or brain injury
This study tests a vision rehabilitation program for people who lost part of their vision on the same side in both eyes after a stroke or brain injury. The program uses flashing lights to help retrain your brain, so it is important that you do not have seizures triggered by lights.
Edmonton, AlbertaAges 18 years+ - NCT06241482Recruiting
Enhanced recovery after brain surgery in intensive care
This study tests a special recovery program for people with serious brain injuries or strokes who need intensive care. The program focuses on helping you heal faster after surgery.
ShanghaiAges 18–75 - NCT06242704Recruiting
Brain training to improve memory and decisions in teens
This study tests if computer-based brain training exercises can help 11-15 year olds improve their memory and decision-making skills. It involves internet sessions over 5-8 weeks.
Flint, MichiganAges 11 years+ - NCT06245109RecruitingPhase 4
Pain medicine study for knee osteoarthritis
This study tests how well different pain medicines work for knee osteoarthritis and looks at brain patterns to understand why some people get more relief. It may help you find a treatment that works best for you.
Chicago, IllinoisAges 41 years+ - NCT06246942Recruiting
Understanding brain connections in healthy adults
This study uses brain scans to learn how different parts of the brain connect and communicate in healthy people. If you join, you will help researchers better understand normal brain function.
Boston, MassachusettsAges 18–64 - NCT06246669Recruiting
Exercise and fear after concussion in college athletes
This study looks at whether prescribed exercise can help college athletes feel less afraid of pain after a concussion. It aims to see if exercise helps them recover better.
Charlottesville, VirginiaAges 18–25 - NCT06248606RecruitingPhase 2
Adagrasib with brain radiation for KRAS G12C lung cancer with brain mets
This study tests a targeted pill (adagrasib) combined with focused radiation to the brain (SRS) for people with KRAS G12C-mutated lung cancer that has spread to the brain. The goal is to see if this combination can control brain tumors while treating the rest of the body.
Columbus, OhioAges 18 years+ - NCT06251635Recruiting
Antipsychotics and brain insulin in women
This study looks at how a common antipsychotic medication (olanzapine) affects how the brain uses insulin in young women. It aims to understand weight gain and metabolic changes linked to these drugs.
Toronto, OntarioAges 18–35 - NCT06254469RecruitingPhase 3
PET scan study for memory decline with head injury or Alzheimer's risk
This trial uses a special PET scan tracer to see if it can predict who will get worse over time. It is for people with mild memory or thinking problems that may be linked to past head injuries or early Alzheimer's disease.
Evanston, IllinoisAges 45 years+ - NCT06265766Recruiting
Brain stimulation for stroke recovery study
This trial tests a type of brain stimulation (called cTBS) to help improve arm movement after a stroke. It is designed for people who have weakness in one arm due to a first stroke and can start treatment within 21 days.
's-HertogenboschAges 18 years+ - NCT06270290Recruiting
Concussions and contact sports in RBD patients versus controls
This trial looks at whether people with REM sleep behavior disorder (RBD) have more concussions or contact sports history than people without RBD, to see if head injuries might be linked to the condition.
London, LondonAges 50 years+ - NCT06280092RecruitingEarly Phase 1
Stem cells plus brain stimulation for epilepsy
This trial is testing if injecting stem cells from a donor during deep brain stimulation (DBS) surgery can help control seizures better than DBS alone. It is for adults with epilepsy that does not respond to medicines.
Jacksonville, FloridaAges 18–75 - NCT06281223Recruiting
Brain and spinal cord connection study in spasticity
This study looks at how the brain and spinal cord connect in children with spasticity (muscle stiffness). It will help doctors understand more about this condition by studying patients who are already scheduled for surgery to reduce stiffness.
NiceAges 3–17 - NCT06286800Recruiting
Personalized brain stimulation for stroke recovery
This study tests a personalized, non-invasive brain stimulation treatment called transcranial direct current stimulation (tDCS) to help improve movement in people who have had a stroke that affects one side of the body. It aims to see if this gentle electrical stimulation can boost recovery of arm and hand function.
Houston, TexasAges 18–80 - NCT06290024Recruiting
Nerve pain study: tracking long-term symptoms
This study follows people with nerve pain over time to learn more about their condition. You will not receive a new treatment, but your data will help doctors understand neuropathic pain better.
Shanghai, YangpuAges 18–85 - NCT06292585Recruiting
Blocking the artery to treat epidural hematoma
This trial tests a new way to treat a blood clot outside the brain (epidural hematoma) after a head injury. Instead of surgery, doctors use a thin tube to block the artery feeding the clot, which may help the body absorb the clot more safely.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06301776Recruiting
Shorter vs. longer blood thinners after bridge stent for neck artery
This trial compares two different lengths of blood-thinner therapy after getting a Bridge stent for a narrowed artery in the back of the neck. It aims to find the best way to prevent future strokes with fewer side effects.
Shenyang, LiaoningAges 18–80
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.