Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,062 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06660225Recruiting
Deep brain stimulation for severe OCD
This trial tests if deep brain stimulation (a surgical treatment that uses electrical pulses to adjust brain activity) can help people with severe obsessive-compulsive disorder (OCD) that has not improved with other treatments. It is for adults aged 22 to 75 who have had OCD symptoms for over 5 years.
Dallas, TexasAges 22–75 - NCT06818864RecruitingPhase 1
Deep brain stimulation for memory after brain injury
This trial tests if deep brain stimulation (DBS) can improve memory and thinking for people who have had a traumatic brain injury. DBS uses a small device placed in the brain to send gentle electrical pulses.
Toronto, OntarioAges 18–70 - NCT06857006Recruiting
Comparing radiation margins for brain tumors
This trial tests two different radiation margins (how much healthy tissue is included around a brain tumor) during a single treatment session. It aims to see which margin is better at controlling brain metastases while reducing side effects.
Birmingham, AlabamaAges 19 years+ - NCT06873477Recruiting
Brain injury study for children and young adults
This study looks at children and young adults who have brain damage from a severe head injury or lack of oxygen at birth. It aims to learn more about these conditions and how to help patients.
Rome, LazioAges Up to 20 years - NCT06914479RecruitingPhase 1
Gene therapy and valacyclovir for recurrent brain tumors in young people
This trial tests a new gene therapy that uses two special viruses and an oral antiviral drug (valacyclovir) to treat brain tumors that have come back in children and young adults. The therapy is given right after surgery to remove the tumor, with the goal of helping your immune system fight the cancer.
Ann Arbor, MichiganAges 3–39 - NCT06921980Recruiting
Cell therapy and brain function in AIHA
This trial looks at how cell therapy may affect your brain function and mood if you have autoimmune hemolytic anemia. It aims to help doctors understand the psychological changes that can happen during treatment.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT06932692Recruiting
Brain network analysis using 7-Tesla MRI in DBS patients
This study uses advanced brain imaging (7-Tesla MRI and MEG) to understand how deep brain stimulation (DBS) affects brain networks in people with Parkinson's disease or essential tremor. It helps doctors learn how DBS works so they can improve treatment in the future.
Amsterdam, North HollandAges 18 years+ - NCT06954610Recruiting
Heart Check for Stroke Risk in Atrial Fibrillation
This trial uses heart imaging to better understand stroke risk in people with atrial fibrillation (an irregular heartbeat). It may help doctors decide on the best treatment to prevent another stroke.
BernAges 18 years+ - NCT06956417Recruiting
Memory rehab after concussion
This trial tests a memory rehabilitation program for people who have had a concussion and still have memory problems. It uses a computer, tablet, or smartphone to help improve memory.
Calgary, AlbertaAges 18–59 - NCT06974370RecruitingPhase 2
Avoiding brain radiation when chemo or other drugs work
This trial tests whether some people with brain metastases from solid tumors can safely skip radiation if their cancer drugs (like targeted therapy, immunotherapy, or certain chemotherapies) shrink the brain tumors. You will get MRI scans to see if the drugs are working.
Burlington, VermontAges 18 years+ - NCT06976788Recruiting
Healthy volunteers needed for brain imaging study on epilepsy
This trial is creating a database of brain scans from healthy people to improve understanding of epilepsy. You would have one PET scan of your brain to help researchers develop new imaging methods.
MarseilleAges 18–65 - NCT07014748Recruiting
Study of a head scanner for combat brain injuries in Ukraine
This trial tests a handheld scanner to help doctors quickly see if a head injury needs further care. You may join if you have a combat-related head injury with signs of brain trauma and no large scalp wounds.
Birmingham, AlabamaAges Any age - NCT07026734Recruiting
Speech and Swallow Effects of Deep Brain Stimulation in Parkinson's
This study looks at how deep brain stimulation (DBS) affects speech and swallowing in people with Parkinson's disease. It aims to help understand changes so doctors can better support you after DBS surgery.
Gainesville, FloridaAges 45–85 - NCT07073378Recruiting
Brain-computer help for youth with severe disabilities
This study tests if a brain-computer interface (a device that reads brain signals) can help children and teens with severe physical or communication challenges do things at home, like moving a cursor or expressing themselves.
Calgary, AlbertaAges 5–18 - NCT07105358Recruiting
Vision recovery study after brain damage
This study tests whether the brain can improve vision after damage caused by stroke, tumor, or injury. It may help people with vision loss from a brain lesion find new ways to see better.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07109804Recruiting
Deep brain stimulation to improve walking after spinal cord injury
This study tests whether stimulating a small area deep in the brain (the cuneiform nucleus) with a device called deep brain stimulation (DBS) can help people walk better after a spinal cord injury. The goal is to see if it improves walking speed and stability.
Miami, FloridaAges 22–70 - NCT07117864Recruiting
T-DXd with brain radiation for HER2+ breast cancer
This trial tests a new combination of a targeted drug (T-DXd) with brain radiation for women with breast cancer that has spread to the brain and is HER2-positive or HER2-low. The goal is to see if this approach is safe and works better than radiation alone.
Beijing, Beijing MunicipalityAges 18–75 - NCT07121582Recruiting
Brain rhythm training for arm recovery after stroke
This trial tests a way to retrain your brain's rhythms after a stroke to help you move your arm and hand better. It uses a non-invasive head coil (TMS) to stimulate the brain while you squeeze a grip device.
Chapel Hill, North CarolinaAges 45–80 - NCT07162246RecruitingPhase 2
Radiosurgery for large brain tumors and metastases
This trial tests a special high-dose radiation treatment for people who have up to two large brain tumors (metastases) and possibly other smaller ones. The treatment aims to control the tumors while limiting radiation to healthy brain tissue.
Toronto, OntarioAges 18 years+ - NCT07166991RecruitingPhase 3
Anesthesia study for organ donation after brain death
This trial compares different anesthesia strategies used during organ donation surgery after brain death to see which one helps preserve organs better for transplant. It is for brain-dead adult patients in the ICU whose families agree to organ donation and research participation.
GrenobleAges 18 years+ - NCT07175077Recruiting
7T MRI scan to find tiny brain metastases in small-cell lung cancer
This trial uses a powerful 7T MRI scanner to detect very small brain metastases in people with small-cell lung cancer who choose not to get preventive brain radiation. The goal is to see if this advanced scan can find hidden spots in the brain that regular MRIs miss.
Columbia, MissouriAges 18 years+ - NCT07187739Recruiting
Mediterranean diet for Parkinson's with deep brain stimulation
This study tests whether a Mediterranean diet can improve nutrition in people with Parkinson's disease who have had deep brain stimulation surgery. It may help you maintain better nutrition and overall health.
Ankara, AnkaraAges 45–64 - NCT07198256Recruiting
AI-assisted diagnosis of brain tumors
This trial tests an AI tool that helps diagnose brain tumors like glioma, brain metastases, and lymphoma using MRI scans. It may allow faster and more accurate diagnosis without needing additional tests.
Hangzhou, ZhejiangAges 18–100 - NCT07682311Recruiting
Adjusting brain stimulation automatically for Parkinson's
This study tests a new way to adjust deep brain stimulation (DBS) automatically during the day to better control Parkinson's symptoms. It is for people who already have a Percept DBS device but still have motor fluctuations.
San Francisco, CaliforniaAges 25–75
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,062 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.