Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,063 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06070025Enrolling by invitation
Military life experiences and psychological health study
This study looks at how experiences before joining the military affect the mental health of active-duty service members. It may help understand what supports are needed for those currently serving.
Oceanside, CaliforniaAges 18 years+ - NCT06019793Enrolling by invitation
Recording brain signals during deep brain stimulation for pain
This study tests whether recording brain activity during deep brain stimulation (DBS) for chronic pain can help improve future treatments. It is for people with long-lasting, severe pain that hasn't been helped by other treatments.
Phoenix, ArizonaAges 22 years+ - NCT05911139Enrolling by invitation
Study how anesthesia affects brain injury markers in craniosynostosis surgery
This study looks at how general anesthesia may affect “brain injury marker” levels during and after surgery for single-suture craniosynostosis in infants. It may help doctors better understand anesthesia timing and safety for babies having corrective surgery.
BratislavaAges Up to 18 years - NCT05882344Enrolling by invitation
Deep brain stimulation for early Alzheimer’s memory problems
This trial tests whether a targeted deep brain stimulation treatment can help people with early Alzheimer’s disease symptoms and memory loss. It also involves brain imaging and a surgery/anesthesia procedure to place the stimulator.
Nashville, TennesseeAges 60–80 - NCT05682248Enrolling by invitation
Testing a brain assessment and stimulation system for unconsciousness
This trial studies a device and plan to assess brain function and deliver an intervention in people who are in a coma, minimally conscious state, or unresponsive arousal state after brain injury, stroke, or lack of oxygen. If you qualify, it may help doctors understand and potentially improve brain function over time.
BeijingAges 14–80 - NCT05624632Enrolling by invitation
Online cognitive tests you can do remotely
This study checks how well an online remote testing approach measures thinking and memory. It may help researchers collect cognitive data more easily, especially by combining it with other related studies.
BarcelonaAges 45–80 - NCT05606991Enrolling by invitation
Testing how CPAP affects brain waste clearance during sleep
This study looks at how stopping CPAP for 14 nights affects “brain waste clearance,” a process your brain uses to clear byproducts during sleep. It is testing whether using CPAP versus stopping it changes this brain cleanup in adults with severe obstructive sleep apnea (OSA).
Macquarie Park, New South WalesAges 35–65 - NCT05563259Enrolling by invitation
Brain and memory testing in fatty liver disease
This study checks how well your brain and memory work in people with non-alcoholic fatty liver disease. It also looks at brain function with special assessments, which may help researchers understand what changes happen with this condition.
Nanjing, JiangsuAges 20–75 - NCT05539378Enrolling by invitation
Study how sleep affects the brain’s self-cleaning process
This study looks at whether improving or tracking sleep changes how the brain “clears” waste. It may help researchers understand sleep’s role in brain health and how to support it.
ZurichAges 50–80 - NCT05450237Enrolling by invitation
Testing thinking and memory questionnaires in people with brain injury
This study checks how well certain questionnaire and testing tools work for people who have brain damage from neurologic conditions and ongoing brain inflammation. It may help future patients by improving which tests are most accurate and easy to use.
Pozzilli, IserniaAges 18–80 - NCT05435859Enrolling by invitation
Mapping the brain area for speech during surgery
This study uses tiny brain electrodes placed during surgery to better understand how a brain region helps with speech. The results may guide safer brain mapping during surgery for people with epilepsy or brain tumors.
San Francisco, CaliforniaAges 18–70 - NCT05152992Enrolling by invitation
Studying brain networks during epilepsy surgery planning
This study looks at how emotion-related brain connections change in space and over time while people with epilepsy are having surgery-related electrodes placed to find seizure sources. It may help researchers better understand brain networks and improve future treatment planning.
San Francisco, CaliforniaAges 18–80 - NCT05101746Enrolling by invitationPhase 2/Phase 3
Nitric oxide to protect brain and kidneys in babies during heart surgery
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Nashville, TennesseeAges birth–1 year - NCT05015881Enrolling by invitationPhase 2/Phase 3
Brain and heart scans in alcohol use disorder
This study uses special brain and heart scans to see how sugar (glucose) is used in people with alcohol use disorder compared with people without it. It may help researchers understand the brain–heart connection in alcohol use disorder.
Philadelphia, PennsylvaniaAges 21–65 - NCT05014841Enrolling by invitation
Brain electrode study of speech across different languages
This study uses electrodes placed on the brain during surgery to understand how speech is represented in different languages. It may help doctors better map language areas and improve surgical planning for people having brain surgery.
San Francisco, CaliforniaAges 18–70 - NCT04482660Enrolling by invitation
PET brain scan study of tau protein in ALFA volunteers
This study uses a special PET brain scan tracer to measure “tau” protein clumps in the brain. It’s meant to better understand brain changes in people who are already part of the ALFA research program, and may help researchers connect tau levels with memory and thinking.
Barcelona, BarcelonaAges 45 years+ - NCT04258774Enrolling by invitation
Breathing challenge during MRI to test brain blood-flow signals
This study uses a breathing challenge while you’re in an MRI to see how blood flow signals in the brain change. It may help researchers better understand how brain imaging signals respond to breathing and oxygen/carbon dioxide levels.
St Louis, MissouriAges 18 years+ - NCT04095026Enrolling by invitation
Brain recording and stimulation to improve memory
This study tests a brain-recording and brain-stimulation approach to help improve memory. It is offered to adults who are already enrolled in a specific epilepsy surgery program and can safely complete memory-related tasks.
Bethesda, MarylandAges 18–65 - NCT04043442Enrolling by invitationPhase 2
Brain stimulation study for alcohol use with mild brain injury
This trial tests a type of brain stimulation to help with day-to-day functioning in people who have alcohol use disorder and a history of mild traumatic brain injury. It also uses brain and symptom testing to see who may benefit most and why.
Hines, IllinoisAges 22–65 - NCT03914768Enrolling by invitationPhase 1
Immune Cell Vaccine for Brain Tumors
This trial tests a vaccine made from immune cells (dendritic cells) designed to train your body to fight brain tumors like DIPG or glioblastoma. You may qualify if you have one of these tumors, have had standard treatment, and are generally healthy enough for the study.
Shenzhen, GuangdongAges 1–75 - NCT03414242Enrolling by invitation
Neck and brain tests after a sports head or neck injury
This study looks at how sports-related injuries may affect thinking and how well your neck moves and feels strong. You may be eligible if you’re an athlete and can do simple neck movement and strength checks.
Scottsdale, ArizonaAges 12–30 - NCT03255408RecruitingPhase 1/Phase 2
Sleep study testing breathing and blood flow in healthy adults
This study looks at how your brain blood flow and breathing change during sleep under normal oxygen and reduced oxygen. It will only include healthy adults so researchers can learn what “intermittent hypoxia” does to the body in people without medical problems.
Calgary, AlbertaAges 18–45 - NCT03021031Enrolling by invitation
Deep brain stimulation for Parkinson’s patients
This trial studies a type of brain stimulation to help reduce symptoms in people with Parkinson’s disease. You may be able to join if you have Parkinson’s and are being considered for this treatment.
Minneapolis, MinnesotaAges 21 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,063 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.