Clinical trials
Breast Cancer Invasive clinical trials
Below are recruiting breast cancer invasive clinical trials, each written for real people, not researchers. We’re tracking 717 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05684367Recruiting
Exercise program to rebuild stamina and energy after breast cancer
This study tests whether a structured exercise program can help older adults with breast cancer regain stamina and reduce fatigue. It focuses on people who are still dealing with moderate fatigue after finishing certain breast cancer treatments.
Gainesville, FloridaAges 60–105 - NCT03448926Recruiting
DCIS test registry to guide radiation and drug decisions
This study collects information from people with breast ductal carcinoma in situ (DCIS) to see how a specific lab test (DCISionRT) may help predict who benefits from radiation and/or certain medications. Your results and clinical details are gathered during routine care, not necessarily to change treatment right away.
Scottsdale, ArizonaAges 30–85 - NCT05999396RecruitingPhase 1
Testing a new antibody for colorectal cancer
This trial tests a new drug called CC-3, which is a type of antibody designed to help your immune system attack colorectal cancer cells. It is for people whose cancer has spread and who have already tried several standard treatments.
Tübingen, Baden-WurttembergAges 18 years+ - NCT07468851RecruitingPhase 1/Phase 2
Study of HS-10566 for high-risk bladder cancer that hasn't spread into muscle
This study tests a new treatment called HS-10566 for people with a type of bladder cancer that has not reached the muscle layer and is considered high-risk, where the usual treatments have not worked or were not an option. It aims to control the cancer and avoid the need for removing the bladder.
BeijingAges 18 years+ - NCT06809140RecruitingPhase 2
Bladder-sparing treatment for muscle-invasive bladder cancer
This trial tests a combination of two drugs, enfortumab vedotin and pembrolizumab, to treat bladder cancer that has grown into the muscle of the bladder. The goal is to shrink or eliminate the cancer so that surgery to remove the bladder may not be needed.
Duarte, CaliforniaAges 18 years+ - NCT06640881RecruitingPhase 2
Repeat breast-conserving surgery with partial reirradiation
This trial tests a new approach for women whose breast cancer has returned in the same breast after earlier surgery and radiation. Instead of removing the whole breast, doctors will remove only the tumor again and give a small, focused dose of radiation before surgery, aiming to preserve the breast.
AmsterdamAges 50 years+ - NCT04349527Recruiting
Comparing breast-conserving surgeries and how you feel after
This trial compares two breast-conserving surgery techniques to see how they affect cosmetic results (how the breast looks), quality of life, and patient satisfaction. It may help guide the best surgical approach for people eligible for breast conservation.
BudapestAges 18–65 - NCT07579117Recruiting
Video-Assisted Breast Surgery With Nipple Preservation
This trial tests a minimally invasive surgical technique that removes breast tissue while preserving the nipple and immediately reconstructing the breast. It may be suitable if you have early-stage breast cancer or are at high genetic risk and need preventive breast removal.
MilanAges 18 years+ - NCT06365788RecruitingPhase 2
Bicalutamide and Abemaciclib for AR-positive Triple-negative Breast Cancer
This trial tests a combination of two oral drugs—bicalutamide and abemaciclib—for people with a specific type of advanced triple-negative breast cancer that grows in response to androgen hormones (AR-positive). The goal is to see if this treatment can shrink tumors or slow disease progression.
AntwerpAges 18 years+ - NCT06086704RecruitingPhase 2
PET/MRI scan for PR-positive breast cancer before surgery
This trial tests a new PET/MRI scan (using a special tracer called 18F-FFNP) to see how it images progesterone-receptor-positive breast cancer before surgery. You would get the scan and then have your planned surgery.
Madison, WisconsinAges 18 years+ - NCT05213962Enrolling by invitation
Radiation after nipple-sparing mastectomy with implant
This study tests local and regional radiation treatment after nipple-sparing mastectomy done with an implant. It may help reduce cancer returning in the breast/nearby tissues for people whose cancer hasn’t spread to distant sites.
Goyang-si, Gyeonggi-doAges 20 years+ - NCT01174121RecruitingPhase 2
Immunotherapy made from your tumor-fighting immune cells
This trial tests a treatment made from your own immune cells (called tumor-infiltrating lymphocytes, or TILs) for certain metastatic cancers. It’s designed for people whose cancer has not responded to standard treatments and who can safely provide a small tumor sample for cell-making.
Bethesda, MarylandAges 18–72 - NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT06731894RecruitingPhase 2
Cannabis for nerve pain after chemotherapy in breast and colon cancer survivors
This trial tests whether a cannabis-based product can reduce nerve damage (neuropathy) caused by chemotherapy in people who have finished treatment for breast or colon cancer. It focuses on survivors who still have pain, numbness, or tingling in their hands or feet.
Duarte, CaliforniaAges 18 years+ - NCT04025164Recruiting
Shorter vs standard breast radiation after lumpectomy
This study compares a shorter course of radiation to a standard longer course after breast-conserving surgery (lumpectomy). It’s meant to see which schedule works just as well while focusing on safety and cancer control.
Guiyang, GuizhouAges 18–70 - NCT05978648RecruitingPhase 2
Trilaciclib for early-stage HR-negative breast cancer after surgery
This trial tests if adding trilaciclib to standard chemotherapy after surgery can help people with hormone receptor-negative breast cancer. It aims to reduce side effects and improve treatment outcomes.
Guangzhou, GangdongAges 18 years+ - NCT07060807RecruitingPhase 3
Patritumab deruxtecan for advanced breast cancer
This study tests an investigational drug called patritumab deruxtecan for people with a certain type of advanced breast cancer that is hormone receptor-positive and HER2-negative. The drug targets a protein called HER3, which is common on these cancer cells, and may slow or shrink the cancer when previous treatments have stopped working.
Daphne, AlabamaAges 18 years+ - NCT06704659Recruiting
Repeated radiation for recurrent breast cancer
This study tests giving a second round of radiation therapy to women whose breast cancer has come back in the same breast, at least 3 years after their first radiation. It may be an option for women 55 and older who have a small, local recurrence that can be removed with surgery.
HelsinkiAges 55 years+ - NCT05072600RecruitingPhase 2
Pembrolizumab after complete bladder cancer treatment response
This trial studies pembrolizumab (an immunotherapy) in people with muscle-invasive bladder cancer who had a combined “trimodality” treatment and then achieved a complete response. The goal is to help control the cancer after the initial treatment is finished.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04222413RecruitingPhase 1
Study of metarrestin for advanced solid tumors
This study tests an experimental drug called metarrestin for people with solid tumors that have spread or come back after standard treatment. It may help by targeting a protein involved in cancer cell growth.
Fairway, KansasAges 12–120 - NCT06493370RecruitingPhase 2
IV vitamin C plus chemo for bladder cancer
This trial tests adding high-dose vitamin C (ascorbate) to a standard chemotherapy combination for people with muscle-invasive bladder cancer who cannot take or choose not to take cisplatin. The goal is to find a more affordable and effective treatment option.
Iowa City, IowaAges 18 years+ - NCT06919965RecruitingPhase 3
TAR-210 vs. standard bladder chemo for high-risk bladder cancer
This trial compares a new drug called TAR-210, given directly into the bladder, to standard chemotherapy for people with a specific type of high-risk bladder cancer that has not invaded muscle. It tests if TAR-210 can be more effective with fewer side effects.
Sun City, ArizonaAges 18 years+ - NCT04601116RecruitingPhase 3
Atorvastatin for hormone-positive breast cancer to prevent recurrence
This Phase 3 study tests whether taking atorvastatin (a cholesterol-lowering medicine) can improve outcomes for women with estrogen-receptor–positive breast cancer. It may help by affecting cancer-related pathways and reducing risk of recurrence or progression.
AarhusAges 18 years+ - NCT07250204Recruiting
Testing nipple discharge to tell benign from malignant breast disease
This study uses a blood test and a sample of nipple discharge to see if it can help doctors tell the difference between non-cancerous and cancerous conditions in the breast ducts. It aims to find a better way to diagnose intraductal disease without needing surgery right away.
Wuhan, HubeiAges 18 years+
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Common questions
- Are there clinical trials for breast cancer invasive?
- Yes. Clin2 currently lists 717 recruiting breast cancer invasive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer invasive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer invasive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.