Clinical trials
Breast Cancer Recurrent clinical trials
Below are recruiting breast cancer recurrent clinical trials, each written for real people, not researchers. We’re tracking 629 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06366347RecruitingPhase 2
Maintenance letrozole and abemaciclib for advanced endometrial cancer
This trial tests whether taking two oral medications (letrozole and abemaciclib) after standard chemotherapy can help keep advanced or recurrent endometrial cancer from coming back. It is for people whose cancer is estrogen receptor-positive and has certain favorable genetic features.
Aurora, ColoradoAges 18 years+ - NCT06465069RecruitingPhase 1
Study of an experimental drug for advanced bladder and other cancers
This trial tests a new drug called LY4052031 for people with advanced or metastatic cancers, especially bladder cancer. The drug aims to slow or stop tumor growth. Doctors will check if it is safe and how well it works.
Duarte, CaliforniaAges 18 years+ - NCT06682793RecruitingPhase 1/Phase 2
Study of A2B395 therapy for solid tumors with EGFR and HLA loss
This trial tests a new cell therapy called A2B395 for cancers that have EGFR, a protein on the cell surface, and have lost a specific marker called HLA-A*02. The therapy uses specially engineered immune cells to target and kill these cancer cells. This may help patients with colorectal, lung, head and neck, breast, kidney, or other solid tumors that are no longer responding to standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT07084558Recruiting
Testing treatment guided by tumor DNA for hormone positive breast cancer
This trial tests whether using a blood test (circulating tumor DNA) can help guide chemo and hormone therapy for early-stage, hormone receptor positive and HER2 negative breast cancer. The goal is to tailor treatment to your tumor's response, potentially reducing unnecessary side effects.
Vienna, AustriaAges 18–100 - NCT06023576RecruitingPhase 2
Blood pressure control during breast cancer chemo
This study tests whether careful blood pressure management can help protect the heart during certain types of chemotherapy (anthracyclines) for breast cancer. Participants will use a smart blood pressure device and may also do an exercise test.
Basking Ridge, New JerseyAges 18 years+ - NCT07835139Recruiting
Shorter radiation schedule after breast implant reconstruction surgery
This trial compares a shorter course of radiation (fewer, larger doses) with the standard longer course for women who have had breast cancer surgery with implant-based reconstruction. It aims to see if the shorter schedule is just as safe and effective for the chest area, while being more convenient.
ShanghaiAges 18 years+ - NCT05899387Recruiting
Study fluid after breast surgery
This study looks at a problem called seroma, which is fluid buildup, after certain breast surgeries. It compares different situations where implants or tissue expanders are used, to better understand what to expect and how to manage it.
Augsburg, BavariaAges 18 years+ - NCT06955702Recruiting
Cryotherapy to Prevent Eyelash Loss from Chemo
This trial tests if cooling the eyelids during chemotherapy can prevent eyelash loss in women with newly diagnosed breast cancer. It is for those who have not yet started treatment.
Santander, CantabriaAges 18 years+ - NCT07594015RecruitingPhase 2
Pembrolizumab and lenvatinib for recurrent endometrial cancer
This trial tests a combination of two drugs, pembrolizumab and lenvatinib, for women whose endometrial cancer has returned after initial treatment with immunotherapy. The goal is to see if this combination can help shrink or control the cancer.
Miami, FloridaAges 18 years+ - NCT06431100Recruiting
A study of TRT therapy for advanced solid tumors
This trial tests a new cell therapy called TRTs for people with advanced cancers like stomach, esophagus, cervical, breast, or lung cancer that no longer respond to standard treatments. The therapy uses your own tumor tissue or fluid to create a personalized treatment.
Zhengzhou, HenanAges 18–75 - NCT07579117Recruiting
Video-Assisted Breast Surgery With Nipple Preservation
This trial tests a minimally invasive surgical technique that removes breast tissue while preserving the nipple and immediately reconstructing the breast. It may be suitable if you have early-stage breast cancer or are at high genetic risk and need preventive breast removal.
MilanAges 18 years+ - NCT07398079Recruiting
Wellness program for breast and gynecological cancer survivors
This study explores whether a structured wellness program can help breast and gynecological cancer survivors feel better after their main treatments. It looks at how an integrative approach, which may include complementary therapies, supports your recovery and quality of life.
BaselAges 18 years+ - NCT06292286Recruiting
Second surgery for recurrent ovarian cancer that responds to platinum
This trial tests whether having a second surgery after initial treatment can help people with ovarian cancer that came back but still responds to platinum-based chemotherapy. It may offer another option to remove remaining tumors and delay further treatments.
Hong KongAges 18 years+ - NCT06365788RecruitingPhase 2
Bicalutamide and Abemaciclib for AR-positive Triple-negative Breast Cancer
This trial tests a combination of two oral drugs—bicalutamide and abemaciclib—for people with a specific type of advanced triple-negative breast cancer that grows in response to androgen hormones (AR-positive). The goal is to see if this treatment can shrink tumors or slow disease progression.
AntwerpAges 18 years+ - NCT06058988RecruitingPhase 2
T-DXd for people with brain cancer
This trial tests a drug called Trastuzumab Deruxtecan (T-DXd) for people with brain tumors that are either glioblastoma or have spread from other cancers. Doctors will see if T-DXd can shrink tumors or slow their growth, and they will collect tumor tissue during surgery or biopsy to study how the drug works.
New York, New YorkAges 18 years+ - NCT07098598RecruitingPhase 2/Phase 3
Using FAPI-PET to diagnose pancreatic cancer
This trial uses a special imaging scan called FAPI-PET to help doctors better diagnose pancreatic cancer. If you are suspected of having pancreatic cancer or a recurrence, this study may help confirm or clarify your diagnosis.
TurkuAges 18–85 - NCT07060807RecruitingPhase 3
Patritumab deruxtecan for advanced breast cancer
This study tests an investigational drug called patritumab deruxtecan for people with a certain type of advanced breast cancer that is hormone receptor-positive and HER2-negative. The drug targets a protein called HER3, which is common on these cancer cells, and may slow or shrink the cancer when previous treatments have stopped working.
Daphne, AlabamaAges 18 years+ - NCT05440227RecruitingPhase 2
PG2 shots to reduce moderate to severe breast cancer fatigue
This Phase 2 trial tests whether PG2 injections can safely reduce moderate to severe fatigue in people receiving chemotherapy for locally advanced, recurrent, or metastatic breast cancer. If you qualify, you may be asked to complete questionnaires and follow study plans for about 8 weeks.
TaipeiAges 20 years+ - NCT06312176RecruitingPhase 3
Study of new drugs for HR+/HER2- advanced breast cancer
This trial tests two new drugs (sacituzumab tirumotecan and pembrolizumab) against standard treatments for a type of advanced breast cancer that is hormone receptor positive and HER2 negative. It's for people whose cancer has worsened despite hormone therapy with a CDK4/6 inhibitor.
Chandler, ArizonaAges 18 years+ - NCT05123482RecruitingPhase 1/Phase 2
Study of an experimental drug for advanced solid tumors
This trial tests a new drug, called AZD8205, alone or with other medicines, for people with advanced or metastatic solid tumors that have not responded to standard treatment. It aims to see if the drug can shrink tumors or slow their growth.
Duarte, CaliforniaAges 18 years+ - NCT05738187Recruiting
Cryotherapy for repeat head and neck cancer after prior radiation
This pilot study tests whether cooling treatment on the tumor area (cryotherapy) can control a repeat head/neck cancer that can’t be removed and has already been treated with radiation. It also checks safety, especially in areas that have received radiation before.
StrasbourgAges 18 years+ - NCT06324357RecruitingPhase 1/Phase 2
Zongertinib for HER2-positive cancers that have spread
This trial tests a new pill called zongertinib, alone or with other drugs, for people with HER2-positive cancers (like breast, stomach, or colorectal cancer) that have spread and are no longer responding to standard treatments. The goal is to find the best dose and see if it can help shrink tumors or slow the disease.
Cerritos, CaliforniaAges 18 years+ - NCT04356209RecruitingPhase 2
Pravastatin for severe radiation breast scar tissue, with e-reports
This trial tests whether pravastatin can improve severe radiation-related breast scarring and breast-related quality of life. It also studies whether using an electronic patient questionnaire (e-PRO) helps patients’ outcomes and support during treatment.
MontpellierAges 18 years+ - NCT06926868RecruitingPhase 2/Phase 3
Study of a new drug versus chemotherapy for advanced triple-negative breast cancer
This trial tests a new investigational drug called izalontamab brengitecan against standard chemotherapy for people with advanced triple-negative breast cancer who cannot receive immunotherapy. The goal is to see if the new drug works better at shrinking or slowing the cancer.
Hot Springs, ArkansasAges 18 years+
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Common questions
- Are there clinical trials for breast cancer recurrent?
- Yes. Clin2 currently lists 629 recruiting breast cancer recurrent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer recurrent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer recurrent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.