Clinical trials
Breast Cancer Surgery clinical trials
Below are recruiting breast cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 1,192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05377996RecruitingPhase 1/Phase 2
Study drug for advanced solid tumors with tumor tissue testing
This early-stage study tests emiltatug leda-dotin (Emi-Le) in people with advanced or recurring solid cancers. It aims to see how the drug works and how safely it can be given, using tumor tissue testing to help understand who may benefit.
Phoenix, ArizonaAges 18 years+ - NCT07492394RecruitingPhase 2
Testing dalpiciclib with or without entinostat and letrozole for early breast cancer
This trial is testing a combination of three drugs (dalpiciclib, entinostat, and letrozole) for women with early-stage, hormone-receptor-positive, HER2-negative breast cancer. It aims to see if adding these medications before surgery can help shrink the tumor.
Shijiazhuang, HebeiAges 18–75 - NCT07505797Recruiting
Ultrasound imaging study for suspicious breast lesions
This study is testing a new ultrasound device (ATUSA) to see how well it can image breast lesions that have been classified as suspicious (BI-RADS 4 or 5). If you have a recent finding that needs further evaluation, this research might help improve detection methods.
Sacramento, CaliforniaAges 18–94 - NCT07507890Recruiting
Nipple-sparing mastectomy through one armpit incision
This trial tests a less invasive surgery for early-stage breast cancer that removes breast tissue through a single small cut in the armpit while keeping the nipple. It may be an option for women with small to medium breasts who are candidates for immediate breast reconstruction.
Candiolo, TurinAges 18 years+ - NCT07510698Recruiting
Same-day awake mastectomy with immediate breast reconstruction
This study tests whether people can have a mastectomy while awake (using numbing medicine instead of general anesthesia) and go home the same day with immediate breast reconstruction. It may be an option if you're healthy enough and have support at home.
Rome, RomeAges 18–75 - NCT07531836Recruiting
Exercise and wellness program before breast cancer surgery
This trial tests whether a personalized exercise and wellness program before surgery helps older adults with breast cancer recover better and stay stronger. You would work with a team to prepare your body for surgery over several weeks.
Pamplona, NavarreAges 65 years+ - NCT07542106Recruiting
Visual Biofeedback vs. Standard Therapy After Breast Cancer Surgery
This study compares a new visual biofeedback program (using real-time visual feedback to guide exercises) with standard physical therapy to help restore shoulder movement, strength, and function in women recovering from breast cancer surgery. The goal is to see which approach helps patients regain mobility and reduce pain more effectively.
Badajoz, BadajozAges 18 years+ - NCT07546695Recruiting
Axillary lymph node surgery choices for HER2+ and triple-negative breast cancer
This study examines the best surgical approach for removing underarm lymph nodes in patients with HER2-positive or triple-negative breast cancer who have received chemotherapy before surgery and still have cancer in their lymph nodes. The goal is to understand whether removing more lymph nodes improves outcomes for these patients.
BaselAges Any age - NCT07547774Recruiting
Sleep Quality Before Breast Surgery and Recovery Outcomes
This study examines how well you sleep before breast cancer surgery and whether it affects your recovery afterward. Researchers will ask about your sleep habits and track your healing to understand the connection.
Ankara, YenimahalleAges 18–70 - NCT07574671Recruiting
Ketogenic Diet Study for Early-Stage Breast Cancer
This study tests whether a ketogenic diet (high fat, low carb) can help change the environment around breast cancer tumors in ways that might slow cancer growth. You'll follow the diet for several months while researchers monitor your health and take measurements.
San Antonio, TexasAges 18 years+ - NCT07579117Recruiting
Video-Assisted Breast Surgery With Nipple Preservation
This trial tests a minimally invasive surgical technique that removes breast tissue while preserving the nipple and immediately reconstructing the breast. It may be suitable if you have early-stage breast cancer or are at high genetic risk and need preventive breast removal.
MilanAges 18 years+ - NCT07579286Recruiting
Skipping lymph node surgery in early breast cancer
This trial tests whether older women with early-stage, slow-growing breast cancer can safely skip removal of underarm lymph nodes during surgery. The goal is to reduce surgery-related side effects while maintaining safety.
Saint Petersburg, Russian FederationAges 60 years+ - NCT07597837Recruiting
Breast Cancer Surgery Outcomes Study
This study collects information about breast cancer surgery outcomes—with or without reconstruction—to help doctors understand what works best for patients. By participating, you'll contribute to research that may improve care for future patients.
Boston, MassachusettsAges 18 years+ - NCT07608081Recruiting
MRI imaging methods to diagnose and assess breast cancer
This study tests advanced MRI imaging techniques to better diagnose breast cancer and evaluate treatment response. If you have a suspicious breast lesion, this trial may help doctors see it more clearly before biopsy or surgery.
Kunming, YunnanAges 18–80 - NCT07612891RecruitingPhase 1/Phase 2
Testing INV-6452 for advanced breast cancer and solid tumors
This study tests a new drug called INV-6452 to see if it is safe and can help control advanced cancers that have grown despite prior treatment. The drug targets specific cancer cell weaknesses, particularly in hormone-sensitive breast cancers without HER2 mutations.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07615751RecruitingPhase 3
New drug combination for advanced HER2-positive breast cancer
This trial tests whether a newer drug called dalpiciclib works better than chemotherapy when combined with two other anti-HER2 drugs (pyrotinib and trastuzumab) for advanced breast cancer that has spread. The goal is to find a treatment that works well with fewer side effects.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07672392Recruiting
Exercise after breast reconstruction surgery
This trial tests whether a structured exercise program after DIEP flap breast reconstruction helps improve physical fitness compared to standard care. It may help women recover strength and well-being after surgery.
Beaumont, DublinAges 18 years+ - NCT07586319Enrolling by invitation
Surgery to improve survival in early-stage spread breast cancer
This study tests whether surgery to remove cancer spots can help people with breast cancer that has spread to a few places live longer. You would receive standard cancer medicines plus surgery if you qualify.
Lahore, Punjab ProvinceAges 18 years+ - NCT07483034Enrolling by invitation
Music therapy for anxiety during breast cancer treatment
This study tests whether listening to specially chosen music while you're in the hospital for breast cancer treatment can help lower anxiety and depression. It also looks at how music might affect certain substances in your blood that are linked to stress and healing.
Zagreb, City of ZagrebAges 18–65 - NCT07298980Enrolling by invitation
Expressive writing for breast cancer patients
This trial tests whether expressive writing (writing about your thoughts and feelings) can help people about to have breast cancer surgery. It is for those who have not had chemotherapy or other treatments before surgery.
Helsingborg, Skåne CountyAges 18 years+ - NCT06900023Enrolling by invitation
Studying better ways to find breast swelling after cancer treatment
This trial looks at new tools to detect lymphedema (breast or arm swelling) after breast cancer treatment. If you had breast-conserving surgery, radiation, and have finished active therapy (except certain hormone treatments), researchers want to see if a simple device can spot fluid buildup early.
Boston, MassachusettsAges 18 years+ - NCT06890871Enrolling by invitationPhase 1/Phase 2
Radiation with immunotherapy and anti-angiogenic therapy for advanced HER2-negative breast cancer
This trial tests a combination of radiation therapy, immunotherapy, and a drug that blocks blood vessel growth for advanced HER2-negative breast cancer that has spread. It is for patients whose cancer has worsened after at least two prior treatments.
Wuhan, HubeiAges 18–75 - NCT06881550Enrolling by invitation
Herbal medicine study for women after breast cancer surgery
This trial tests whether a Chinese herbal medicine (Shenbailing granules) can help improve energy and blood health in women recovering from breast cancer surgery.
Shenyang, Chian/LiaoningAges 18–75 - NCT06768268Enrolling by invitationPhase 1/Phase 2
Better lymph node imaging for breast cancer
This trial tests whether adding two common fluids (Mannitol and Voluven) before an ICG dye injection can help surgeons better see the lymph nodes that need to be removed during breast cancer surgery. It aims to make sentinel lymph node biopsies more accurate and safer.
Hsinchu CountyAges 20–70
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Common questions
- Are there clinical trials for breast cancer surgery?
- Yes. Clin2 currently lists 1,192 recruiting breast cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.