Clinical trials
Breast Cancer Surgery clinical trials
Below are recruiting breast cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 1,194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07238894Recruiting
Freezing and heating breast cancer without surgery
This study tests a combination of freezing and heating (cryoablation and thermal ablation) to treat breast cancer in patients who cannot have surgery. It may help shrink or control tumors while avoiding general anesthesia.
BeijingAges 18–80 - NCT04947189RecruitingPhase 1/Phase 2
Seviteronel plus chemo for advanced triple-negative breast cancer
This trial tests seviteronel together with standard chemotherapy to treat certain types of advanced breast cancer that has spread. It’s looking to see how well the combination works and how safe it is, especially for cancers that are androgen-receptor positive.
Darlinghurst, New South WalesAges 18 years+ - NCT04947280RecruitingPhase 1/Phase 2
Radiation split into small doses for breast cancer bone spread
This trial studies a type of focused radiation given in smaller parts to treat bone metastases from breast cancer. It may help shrink tumors and improve control of pain or growth when standard treatments haven’t worked or surgery isn’t possible.
Shanghai, Shanghai MunicipalityAges Any age - NCT05327543Recruiting
Online yoga program for better quality of life
This study tests whether doing online yoga can improve quality of life in people with non-metastatic breast cancer. It’s meant to help with day-to-day well-being after cancer treatment.
Berlin, State of BerlinAges 18–75 - NCT05440149RecruitingPhase 3
Radiation after surgery for certain node-positive breast cancer
This study tests whether giving radiation after breast surgery can improve outcomes for people with breast cancer that has spread to nearby lymph nodes (N1). You may be a candidate if you’ve already had surgery and meet specific details about your lymph nodes and cancer type.
Seoul, Jongro-guAges 19 years+ - NCT05603078Recruiting
Breast cancer surgery with a tumor-bed boost and standard radiation
This study looks at whether adding extra targeted radiation to the tumor area before breast-conserving surgery, then using modern breast surgery techniques and whole-breast radiation afterward, improves outcomes for early-stage breast cancer. You may be offered a treatment plan designed to better treat the area where the tumor was removed.
Beijing, Beijing MunicipalityAges Up to 55 years - NCT05906407Recruiting
Genetic-guided treatment planning for high-risk early breast cancer
This study uses tumor genetic testing to help plan more precise treatment for people with early high-risk breast cancer. You may be asked to give a recent tumor sample so researchers can match your cancer features with the best available options.
AugsburgAges 18–80 - NCT05989828RecruitingPhase 1
Engineered immune cells for advanced triple-negative breast cancer
This trial tests a personalized treatment where your own immune cells are modified to recognize and attack cancer cells that have a specific marker called NY-ESO-1. It is for people with triple-negative breast cancer that has not responded to at least two prior treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT06148038RecruitingPhase 1
CBD oil for breast cancer before surgery
This trial tests if taking CBD oil before surgery can help treat invasive breast cancer. It is for women with fast-growing tumors who are scheduled for surgery.
Charleston, South CarolinaAges 18 years+ - NCT06375187RecruitingPhase 1
GC203 TIL for advanced solid tumors
This trial tests an experimental TIL therapy (GC203) for people with advanced solid tumors who have no more standard options. Doctors will take a piece of your tumor, make it into a personalized cell treatment, and give it back to try to fight the cancer.
ShanghaiAges 18–75 - NCT06582017RecruitingPhase 1
Study of QXL138AM for advanced solid tumors and multiple myeloma
This trial tests an investigational drug called QXL138AM for people with advanced solid tumors or multiple myeloma that has not responded to standard treatments. The goal is to see if the drug is safe and effective.
Los Angeles, CaliforniaAges 18 years+ - NCT06444269RecruitingPhase 2
Precision radiation before surgery for early hormone-positive breast cancer
This trial tests a focused radiation treatment before surgery for early-stage breast cancer that is hormone receptor positive and HER2 negative. The goal is to give precise radiation only to the tumor, with the hope of reducing side effects and improving outcomes.
Dallas, TexasAges 18 years+ - NCT06697158Recruiting
Lymphedema therapy and its effect on sleep and quality of life
This study tests a treatment called complex decongestive physiotherapy for women who have swelling in one arm after breast cancer surgery. It looks at whether this therapy can improve their sleep and overall quality of life.
BoluAges 18–85 - NCT06738966RecruitingPhase 1
BL0175 for advanced HR-positive breast or gynecologic cancer
This trial tests a new drug called BL0175 for women with certain types of advanced breast, ovarian, or endometrial cancer that have stopped responding to hormone therapy. The goal is to see if the drug can help shrink tumors or slow down the cancer.
Changchun, JilinAges 18 years+ - NCT06911970Recruiting
Exercise and immune response in cancer treatment
This trial tests whether aerobic exercise can help your immune system fight cancer better during chemotherapy or immunotherapy. It is for people with breast or colon cancer that has not spread to other parts of the body.
Sherbrooke, QuebecAges 40–70 - NCT06920810RecruitingPhase 4
Mistletoe extract plus pembrolizumab for triple-negative breast cancer
This trial tests adding a mistletoe extract (Viscum album) to standard immunotherapy (pembrolizumab) for people with triple-negative breast cancer who have had surgery and radiation. The goal is to see if the combination works better than immunotherapy alone.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT07070778Recruiting
Arterial stiffness study for breast cancer survivors
This study looks at how breast cancer treatment affects artery health. It tests whether artery stiffness is linked to recovery, and may help guide future rehabilitation programs.
Ankara, StateAges 40–69 - NCT07108309RecruitingPhase 2
Study of BCD-236 with chemotherapy for recurrent triple-negative breast cancer
This trial tests a new drug called BCD-236 combined with chemotherapy for people with triple-negative breast cancer that has come back or spread. It may be an option if your cancer is AXL-positive and you have tried at least one prior treatment.
BrestAges 18–74 - NCT07135661Recruiting
Comparing two proton radiation schedules for early breast cancer after lumpectomy
This study compares two types of proton radiation after lumpectomy for early breast cancer. It tests whether a shorter, stronger course (ultra-hypofractionated) works as well as a slightly longer moderate course.
ShanghaiAges 40 years+ - NCT07394387RecruitingPhase 2
HIFU with or without immunotherapy before chemo for triple-negative breast cancer
This trial tests whether adding focused ultrasound (HIFU) and an immunotherapy drug (PD-1 inhibitor) before standard chemotherapy can improve outcomes for women with stage II or III triple-negative breast cancer (TNBC). It aims to find a more effective way to shrink tumors before surgery.
Nanjing, JiangsuAges 18–70 - NCT07418125Recruiting
Study of tumor cell clusters in high-risk early breast cancer
This trial looks at whether clusters of tumor cells in the blood can give more information about high-risk early breast cancer. It is for people with certain types of breast cancer who are about to start treatment before surgery (neoadjuvant therapy).
LjubljanaAges 18 years+ - NCT06470347RecruitingPhase 1/Phase 2
Testing Pyrrolitinib After Trastuzumab for HER2+ Breast Cancer
This study tests if taking pyrrolitinib (a targeted medicine) can further reduce the risk of breast cancer returning in patients with HER2-positive early breast cancer who have already received trastuzumab after surgery.
Zunyi, GuizhouAges 18–75 - NCT06910657RecruitingPhase 1
IDOV-Immune vaccine for advanced solid tumors
This trial tests an experimental virus-based treatment for people with advanced solid tumors that have stopped responding to standard therapies. The treatment is designed to infect and destroy cancer cells while boosting the immune system.
St Louis, MissouriAges 18 years+ - NCT07264985Recruiting
Gut bacteria and diarrhea in breast cancer patients on pyrotinib
This study looks at how gut bacteria relate to diarrhea in breast cancer patients who are taking a drug called pyrotinib. By understanding this link, doctors hope to better manage side effects in the future.
Wuhan, HubeiAges 18–75
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Common questions
- Are there clinical trials for breast cancer surgery?
- Yes. Clin2 currently lists 1,194 recruiting breast cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.