Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,622 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04886531RecruitingPhase 2
Pre-surgery neratinib plus hormone therapy with trastuzumab
This study tests whether a pre-surgery treatment plan that adds neratinib to hormone therapy and trastuzumab can shrink HER2-positive, ER-positive breast cancer before surgery. It may help patients by improving how much cancer is eliminated at the time of surgery.
Chicago, IllinoisAges 18 years+ - NCT04608357Recruiting
Testing digital patient avatars to guide treatment for metastatic breast cancer
This study tests whether a computer “avatar” made from your health information can help choose the best systemic therapy (medications that treat cancer throughout the body) for metastatic breast cancer. You may be asked to provide a tissue sample (biopsy) so the team can build and guide the treatment plan.
Toronto, OntarioAges 18 years+ - NCT04683679RecruitingPhase 2
Radiation plus pembrolizumab and olaparib for certain breast cancers
This study tests whether adding the drugs pembrolizumab and olaparib (or similar “radiosensitizers”) to radiation can improve outcomes for women with advanced breast cancer that is triple-negative or ER-positive/Her2-negative. It’s designed for cancers that have spread or come back and where radiation is being considered to control disease.
Basking Ridge, New JerseyAges 18 years+ - NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT02476786RecruitingPhase 2
Hormone treatment only for older ER-positive breast cancer
This Phase 2 study tests whether using hormone (endocrine) treatment alone can control breast cancer in people age 70 and older. It targets breast cancers that are estrogen-receptor positive and HER2 negative, aiming to avoid chemotherapy-like treatments in suitable patients.
St Louis, MissouriAges 70 years+ - NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT04305834RecruitingPhase 2
Abemaciclib plus hormone pills for metastatic breast cancer in older adults
This Phase 2 study tests whether abemaciclib combined with standard hormone (endocrine) therapy can better control metastatic breast cancer in people age 70 and older. It may help if your cancer has already grown despite prior hormone therapy and/or other cancer medicines.
Duarte, CaliforniaAges 70 years+ - NCT04150042RecruitingPhase 1
Test of chemotherapy plus your own stem cells for metastatic cancer
This Phase 1 trial tests a treatment approach using standard chemotherapy along with stem cells taken from you to treat metastatic pancreatic or breast cancer. It is mainly designed to check safety and find the best way to give the treatment, and it may offer an option for people whose cancer has spread.
Boston, MassachusettsAges 18 years+ - NCT03730922Recruiting
Delayed vs immediate breast reconstruction after mastectomy and radiation
This study compares two timing options for rebuilding the breast after mastectomy followed by radiation: a reconstruction done later (delayed) versus one done sooner (delayed-immediate). The goal is to see which approach works better and is safer for recovery after treatment.
AabenraaAges 18 years+ - NCT03646955Recruiting
Partial breast radiation versus no radiation after lumpectomy
This trial compares giving radiation only to part of the breast versus not giving radiation at all after breast-conserving surgery. It’s meant for women with early, hormone-driven breast cancer to see if skipping radiation can be safe and reduce treatment burden.
SantiagoAges 60 years+ - NCT03356132Recruiting
Breast implant safety and satisfaction follow-up study
This study looks at side effects and satisfaction after breast implant surgery. It may help by sharing what problems happen most and how satisfied people feel after getting a Silimed® textured or Silimed foam-coated implant.
Niterói, Rio de JaneiroAges 18 years+ - NCT07673588Recruiting
Instagram and podcast study for breast cancer awareness in young women
This study tests whether combining Instagram posts with podcast episodes can help women aged 20-39 learn more about breast cancer and get recommended screenings. It aims to make health information easy to access and understand.
AnkaraAges 20–39 - NCT01185132RecruitingPhase 3
IMRT versus partial-breast radiation after lumpectomy
This study compares two different ways of giving radiation to the breast after lumpectomy for early-stage breast cancer. It may help determine which approach controls the cancer well while reducing radiation to surrounding healthy tissue.
Aurora, ColoradoAges 40 years+ - NCT07482384Recruiting
Support program for young women with early-stage breast cancer
This study tests a mobile health program that provides support and information to young women with early-stage breast cancer who are on hormone therapy. The goal is to help you stay on your treatment and manage side effects.
Boston, MassachusettsAges 18–49 - NCT07631052RecruitingPhase 2
Low-dose Capecitabine for High-risk Early Breast Cancer
This study tests whether a low-dose chemotherapy pill called capecitabine can help prevent breast cancer from coming back in patients whose cancer shows signs of remaining disease (called MRD) despite standard treatment. The trial focuses on hormone-receptor-positive, HER2-negative breast cancers.
Toronto, OntarioAges 18 years+ - NCT07635147Recruiting
Decision Support Tool for Advanced Breast Cancer
This study tests a digital tool designed to help patients with advanced (stage IV) breast cancer make treatment decisions. The tool may help you understand your options and feel more confident discussing them with your doctor.
Brooklyn, New YorkAges 18 years+ - NCT07460752RecruitingPhase 2
Alternative injection site for goserelin in breast cancer patients
This trial is testing whether giving the drug goserelin in a different spot on the body works just as well for suppressing ovarian function in premenopausal women with hormone receptor positive breast cancer. You may be a fit if you've already been on goserelin shots in your abdomen for at least 6 months.
Rochester, MinnesotaAges 18–50 - NCT07798466Enrolling by invitation
Immediate breast reconstruction and radiation timing after breast cancer surgery
This trial studies whether getting radiation therapy right after breast reconstruction surgery is safe and effective for women with invasive breast cancer who had chemotherapy before surgery. It aims to improve outcomes and quality of life for patients needing both treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05837455RecruitingPhase 2
Biomarker-guided treatment for early breast cancer before surgery
This trial looks at whether using tumor test results (biomarkers) can help guide the best hormone treatment and chemotherapy before surgery. It focuses on people with stage II or III, ER-positive, HER2-negative breast cancer, with the goal of improving how well the tumor responds before it is removed.
St Louis, MissouriAges 18 years+ - NCT07407920RecruitingPhase 2
Optimizing treatment for early HER2+ and triple-negative breast cancer
This trial aims to see if patients who had a complete response to chemo before surgery can safely stop or reduce their targeted therapy afterward. It includes people with early-stage HER2-positive or triple-negative breast cancer who had no cancer cells left in the tissue removed at surgery (a pathological complete response).
Houston, TexasAges 18 years+ - NCT07415499Recruiting
Breast density impact on mammography screening
This study looks at how breast density affects the ability of mammograms to find breast cancer. It involves women who had a mammogram through a specific screening program.
Verduno, Italy/CNAges 45–75 - NCT07447414Recruiting
Freezing small hormone-driven breast cancers
This study tests cryoablation (freezing) to treat small, early stage breast cancers that are hormone receptor positive and HER2 negative. It may be an option for postmenopausal women who want to avoid surgery.
Lugo, LugoAges Any age - NCT07366112RecruitingPhase 2
CDK4/6 inhibitor plus hormone therapy before breast cancer surgery
This trial tests a combination of a CDK4/6 inhibitor (a type of targeted therapy) with hormone therapy given before surgery for early-stage breast cancer that is hormone receptor-positive and HER2-negative. It aims to see if this approach can shrink tumors and improve outcomes.
Beijing, Beijing MunicipalityAges 18–75 - NCT07365267Recruiting
3D printed mesh for breast reconstruction after mastectomy
This trial tests a new 3D printed biodegradable mesh used during breast reconstruction right after a mastectomy for breast cancer. It aims to see how well the mesh works for cosmetic results and safety.
Xi'an, ShaanxiAges 18–70
Hear when a new Breast trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,622 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.