Clinical trials
Cancer Surgery clinical trials
Below are recruiting cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 862 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06272461Recruiting
Comparing lidocaine vs. ketamine for colorectal surgery pain
This trial compares two pain-relief medicines (lidocaine vs. ketamine) given through an IV during open colorectal surgery. It aims to find which one works better to reduce pain after surgery.
NabeulAges 18–90 - NCT06818552Recruiting
Vascular surgeon's role in orthopedic tumor surgery
This trial is looking at how a vascular surgeon can help during surgery for tumors that involve blood vessels. It may help people with bone or soft tissue tumors that are close to or wrapped around major blood vessels.
Bologna, ItaliaAges 18 years+ - NCT06839001RecruitingPhase 3
Freezing small breast tumors instead of surgery trial
This study tests if freezing a very small early-stage breast tumor (cryoablation) can be as effective as surgery. It may be an option for people whose tumor is small enough and hasn't spread to lymph nodes or elsewhere.
São Paulo, São PauloAges 18 years+ - NCT07071207Recruiting
Text reminders after prostate surgery
This trial tests if text message reminders help men recover urinary control after prostate surgery. If you are planning prostate surgery and can use a mobile phone for texts, you may be able to join.
Rochester, New YorkAges 18 years+ - NCT07200544RecruitingPhase 4
Meloxicam for skin cancer surgery pain
This study tests if meloxicam, an anti-inflammatory painkiller, helps control pain after Mohs surgery for skin cancer. It aims to reduce the need for stronger opioid pain medicines.
Oklahoma City, OklahomaAges 18–110 - NCT07241663Recruiting
Surgery for locally advanced pancreatic cancer
This trial is testing whether surgery can help people with a certain type of pancreatic cancer that is locally advanced but not yet spread. You may join if your cancer has shrunk or stayed stable after at least 4 months of chemotherapy and your medical team thinks surgery is possible.
PadovaAges 18 years+ - NCT07618624Enrolling by invitationPhase 2
Drug combination before surgery for recurrent head and neck cancer
This trial tests three drugs (finotonlimab, cetuximab, and docetaxel) given before surgery to remove recurrent head and neck cancer in patients whose cancer stopped responding to previous immunotherapy. The goal is to shrink the tumor and improve surgical outcomes.
Foshan, GuangdongAges 18–75 - NCT07759193Recruiting
Understanding energy needs after head and neck cancer surgery
This study measures how many calories patients burn before and after reconstructive surgery for head and neck cancer. It aims to help doctors provide better nutrition during recovery.
Tel AvivAges 18–120 - NCT07457346RecruitingPhase 2
Testing emactinib with chemo and immunotherapy before head and neck cancer surgery
This trial tests whether combining the drug emactinib with chemotherapy and immunotherapy before surgery helps treat advanced head and neck cancer. It aims to shrink tumors and make surgery more effective.
Hangzhou, ZhejiangAges 18–75 - NCT07024615RecruitingPhase 1
Study of ASP2138 before surgery for pancreatic cancer
This study tests an experimental drug, ASP2138, given before surgery for pancreatic cancer that is still removable. After surgery, you will receive standard chemotherapy. The goal is to see if adding ASP2138 before surgery helps improve outcomes.
Boston, MassachusettsAges 18 years+ - NCT06059651Recruiting
Bariatric Surgery and its Effects on Fat, Immune Cells, and Cancer
This study looks at how bariatric (weight-loss) surgery affects fat metabolism, immune cells, and cancer risk in women with severe obesity and high cholesterol. If you are a woman aged 35–60, White or Black, with a BMI of 40 or higher and high triglycerides or LDL, you may be eligible.
Baton Rouge, LouisianaAges 35–60 - NCT06194708Recruiting
Why some temporary stomas are never reversed after rectal cancer surgery
This trial looks at why some people who had a temporary stoma (a bag for waste) after rectal cancer surgery never get it reversed. It collects information from medical records to find patterns that might explain this.
Beijing, Beijing MunicipalityAges 18–100 - NCT06291064RecruitingPhase 2
Chemotherapy study for Nigerian women with triple-negative breast cancer
This trial studies a standard chemotherapy treatment for Nigerian women with triple-negative breast cancer that has not spread widely. It aims to see how well the treatment works and how safe it is.
Ikeja, LagosAges 18–70 - NCT06805045Recruiting
Image-guided surgery for rectal cancer
This trial uses special imaging to guide surgery for rectal cancer. It studies whether detailed scans taken before surgery can help doctors remove the cancer more precisely.
BolognaAges 18–80 - NCT04288999RecruitingPhase 3
Surgery plus chemo versus chemo-radiation then surgery for recurrent rectal cancer
This study compares two treatment plans for locally recurrent rectal cancer: (1) surgery plus chemo, or (2) chemo plus radiation first, then surgery, followed by chemo. It aims to see which approach works better in controlling the cancer and helping patients recover.
ChibaAges 20–80 - NCT00001823Recruiting
Surgery Branch Screening for Cancer Treatment Studies
This is a screening evaluation to see if you might be eligible for cancer treatment research studies at the National Cancer Institute's Surgery Branch. Doctors will review your medical history, imaging, and test results to determine which clinical trials might be right for you.
Bethesda, MarylandAges 18 years+ - NCT05194878RecruitingPhase 3
Before-surgery chemotherapy vs immediate surgery for colon cancer
This trial compares giving chemotherapy before surgery versus going straight to surgery for certain stage II/III colon cancers. It may help shrink the tumor and improve outcomes by testing which approach works best for high-risk cases.
Guangzhou, GuangdongAges 18–75 - NCT06587152Enrolling by invitation
Robotic surgical system trial for chest and belly surgeries
This trial uses a robotic system to assist surgeons during chest and belly surgeries. It aims to see if the robot is safe and effective for procedures like hernia repair, gallbladder removal, or hysterectomy.
Hangzhou, ZhejiangAges 18–80 - NCT06362616Recruiting
Pre-surgery partial breast radiation for recurrent breast cancer
This trial tests a shorter course of radiation to just part of the breast before surgery for women who have had breast cancer return in the same breast. It's for those who have already had radiation to that breast and have a specific type of cancer (ER+, HER2-).
AmsterdamAges 51 years+ - NCT04460352RecruitingPhase 3
Esophageal cancer treatment with chemoradiation plus planned surgery
This trial tests the best way to treat locally advanced squamous cell esophageal cancer: either chemoradiation followed by planned surgery, or monitoring with surgery only if needed. It may help you choose a strategy that controls the cancer while aiming to reduce unnecessary procedures.
Montreal, QuebecAges 18–80 - NCT05797077RecruitingPhase 3
After-surgery blood test–guided therapy for colon cancer liver spread
This Phase 3 trial tests whether an added “maintenance” treatment after liver surgery can help prevent colorectal cancer from coming back. It is only for people whose blood test (ctDNA) still shows signs of cancer after their operation.
Guangzhou, GuangdongAges 18–75 - NCT06690528RecruitingPhase 2
Surgery vs. palliative care for pancreatic cancer with limited liver spread
This trial compares surgery to remove the primary tumor and up to 3 liver spots against standard palliative care for people with pancreatic cancer that has spread only to the liver (up to 3 spots). It is for those whose cancer has not grown after initial chemotherapy and who are healthy enough for surgery.
Padova, ItalyAges 18–75 - NCT07182682RecruitingPhase 3
Sunvozertinib after surgery for early-stage NSCLC with certain EGFR mutations
This trial tests the drug sunvozertinib given after surgery to see if it prevents lung cancer from coming back. It is for people with early-stage non-small cell lung cancer that has specific changes in the EGFR gene (exon20 insertion or PACC mutations).
BeijingAges 18 years+ - NCT00897117Recruiting
Providing tumor tissue samples during lung cancer surgery
This study collects and analyzes tumor tissue from people with early-stage non-small cell lung cancer who are planning surgery. It may help researchers learn more about the cancer by studying samples taken at the time of your operation.
Nashville, TennesseeAges 18–120
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Common questions
- Are there clinical trials for cancer surgery?
- Yes. Clin2 currently lists 862 recruiting cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.