Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03717844Recruiting
Registry for adults with plasma cell disorders
This study is a registry that collects information about adults with plasma cell disorders (conditions involving abnormal antibody-producing cells). It may help researchers understand these diseases better and improve future care by tracking patients over time.
Chapel Hill, North CarolinaAges 18 years+ - NCT03721068RecruitingPhase 1
CAR T-cell treatment for hard-to-treat childhood tumors
This Phase 1 study tests an experimental CAR T-cell treatment that targets GD2, with added immune-boosting and safety features, for children with relapsed or refractory neuroblastoma or osteosarcoma. It’s designed to see if the treatment is safe and can shrink these cancers when standard therapy hasn’t worked.
Atlanta, GeorgiaAges 1.5 years+ - NCT03736863RecruitingPhase 2
Testing combinations of medicines for advanced throat cancer
This trial tests a combination of medicines to treat advanced esophageal squamous cell carcinoma (throat/esophagus cancer) that cannot be removed by surgery and has spread or come back. It is for people whose first treatment (chemotherapy or immunotherapy) did not work well or was not tolerated.
Zhengzhou, HenanAges 18–75 - NCT03747588Recruiting
Laparoscopic versus open surgery for pancreas cancer
This study compares two ways of doing pancreaticoduodenectomy (a major surgery to remove parts of the pancreas and nearby tissue): minimally invasive (often smaller incisions) versus open surgery. It may help clarify which approach works best when the cancer looks potentially removable.
Beijing, Beijing MunicipalityAges 18–75 - NCT03749980Recruiting
Study following people with von Hippel-Lindau (VHL)
This study follows people who have von Hippel-Lindau (VHL) over time to better understand how the condition changes. It may help doctors plan future treatments by collecting long-term health information.
Boston, MassachusettsAges Any age - NCT03748485Recruiting
Chemo after surgery for certain stage III colon cancer
This trial studies whether adding chemotherapy after surgery helps people with colon cancer that was diagnosed before surgery as stage III and later found to be without certain high-risk features. It may help lower the chance the cancer comes back, but you must meet specific surgery and health criteria.
Guangzhou, GuangdongAges 18–75 - NCT03750513RecruitingPhase 1
Tested improved radiation targeting for children with ependymoma
This early-phase study tests a more precisely targeted type of radiation for children with ependymoma, aiming to treat the brain tumor more accurately. It may help reduce how much healthy tissue gets radiation, and researchers are checking safety and best dosing.
Boston, MassachusettsAges Up to 22 years - NCT03758976Recruiting
Study of scans in advanced breast cancer recurrence
This study looks at people with advanced breast cancer to better understand recurrence by using information from recent scans. It may help researchers improve how advanced disease is assessed and followed over time.
LundAges 18 years+ - NCT03760575RecruitingPhase 1
Pembrolizumab plus chemo with surgery for pleural mesothelioma
This trial studies how well pembrolizumab (an immune therapy) works when added to chemotherapy before image-guided surgery for malignant pleural mesothelioma. It aims to shrink or control the cancer and improve surgical results by combining treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03769129Recruiting
Pembrolizumab plus lung ablation for advanced lung cancer
This trial tests whether combining pembrolizumab (an immune treatment) with a lung ablation procedure can be safer and more effective for advanced non-small cell lung cancer after standard first treatment fails or the cancer comes back. It may help shrink tumors and improve control of the disease.
Guangzhou, GuangdongAges 18 years+ - NCT03767075RecruitingPhase 2
Basket trial matching cancer patients to targeted treatments
This trial tests whether matching your tumor’s DNA/RNA results to a specific cancer medicine can work better than standard options when cancer has spread or can’t be removed by surgery. You may be assigned to a “basket” (sub-study) based on the exact changes found in your tumor.
VillejuifAges 18 years+ - NCT03784924Recruiting
Prostate MRI study to find blood and urine cancer signals
This study enrolls men who may have prostate cancer but do not yet have a diagnosis. It uses prostate MRI along with blood and urine tests to see if specific signals can help identify prostate cancer sooner.
Ann Arbor, MichiganAges 18 years+ - NCT03785288RecruitingPhase 3
Testing different schedules of vaginal radiation after hysterectomy
This trial compares different “fractionation” schedules (how often and how many treatments) of vaginal brachytherapy radiation given after surgery for certain early-stage endometrial cancer. It may help find a plan that works well while aiming to control side effects.
Baltimore, MarylandAges 18 years+ - NCT03791034Recruiting
Blood DNA test to guide treatment in early lung cancer
This trial studies a “cell-free DNA” blood test to help diagnose and guide treatment decisions for early non-small cell lung cancer. It may help doctors tailor care based on genetic signals seen in the blood before and around surgery.
SeoulAges 18–90 - NCT03789721Recruiting
ALD registry study for patients and families in the U.S.
This study builds a national registry to better understand adrenoleukodystrophy (ALD) in patients and families. You may help researchers learn how ALD affects people over time and improve future care.
Minneapolis, MinnesotaAges Any age - NCT03791073Recruiting
Looking for New Markers in Pancreatic Cancer
This study looks for new markers in the blood or tissue of people with a pancreatic mass that might be cancer. It uses samples from a routine biopsy or surgery to help doctors learn more about the disease.
Montpellier, MontpellierAges 18 years+ - NCT03796559Recruiting
Magnetic marker helps find breast cancer lymph nodes
This study uses a tiny magnetic marker (called Magseed) placed in a breast cancer–affected underarm lymph node, then tracks whether surgeons can find and remove the correct nodes after chemotherapy. It may help reduce the chance of missing cancer in the underarm while aiming for more accurate surgery.
Houston, TexasAges 18 years+ - NCT03800693RecruitingPhase 2
Shorter vs longer oxaliplatin infusions for gut cancer
This Phase 2 study compares giving oxaliplatin by IV for 2 hours versus 6 hours, along with the standard FOLFOX6 chemotherapy. It aims to see if the shorter infusion works as well and is manageable for people with gastrointestinal cancers.
Atlanta, GeorgiaAges 18 years+ - NCT03803787RecruitingPhase 2
Inhaled steroid to prevent lung inflammation during cancer treatment
This trial tests whether breathing in steroid medicine before and during radiation can lower how often and how badly “radiation lung inflammation” (radiation pneumonitis) happens in people with lung cancer. If you qualify, it may help protect your lungs while you receive radiation with chemotherapy or targeted therapy.
Mexico CityAges 18–75 - NCT03804320Recruiting
Watching small kidney tumors over time instead of treating
This study follows people with small, solid kidney tumors using active surveillance (regular monitoring) rather than immediate surgery or treatment. It may help you understand whether careful watching is a safe option for certain early kidney tumors.
MilanAges 50 years+ - NCT03819829Recruiting
Blood sampling study for healthy adults’ immune responses
This study takes small blood samples to learn how the immune system works in healthy people. It may help researchers better understand immune biology for future treatments, while you help by participating in regular research blood draws.
AmsterdamAges 36 years+ - NCT03830320RecruitingPhase 1
PET scan to look for blood clots in the heart or lungs
This Phase 1 study uses a PET scan to detect blood clots (thrombosis) in specific groups of people. It’s testing how well the scan can find clots and how it should be timed with other heart or illness tests.
Boston, MassachusettsAges 18–85 - NCT03829254RecruitingPhase 1/Phase 2
NUC-7738 treatment for advanced solid cancers and lymphoma
This early-phase study tests how safe NUC-7738 is and how it works in people with advanced solid tumors and certain lymphomas. Some participants may also receive pembrolizumab for specific cancers, aiming to improve cancer control while carefully monitoring side effects.
CambridgeAges 18 years+ - NCT03830151RecruitingPhase 1
C-13 pyruvate MRI to help diagnose brain gliomas
This early-phase study tests a special MRI scan using C-13 pyruvate to help identify and understand gliomas (a type of brain tumor) in people with brain tumors going to surgery or biopsy. It may help doctors see tumor signals better before or around the time of your procedure.
Houston, TexasAges 19 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.